Record Display for the EPA National Library Catalog


Main Title Half-Life of Polychlorinated Biphenyls in Occupationally Exposed Workers.
Author Phillips, D. L. ; Smith, A. B. ; Burse, V. W. ; Steele, G. K. ; Needham., L. L. ;
CORP Author Corvallis Environmental Research Lab., OR. ;Centers for Disease Control, Atlanta, GA. Center for Environmental Health and Injury Control. ;Indiana State Board of Health, Indianapolis. ;National Inst. for Occupational Safety and Health, Cincinnati, OH. Div. of Surveillance, Hazard Evaluations and Field Studies.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/416;
Stock Number PB90-245788
Additional Subjects Half life ; Metabolism ; Blood ; Reprints ; Occupational exposure ; Polychlorobiphenyl compounds ; Aroclors ; Enzyme induction ; Environmental exposure pathways ; Pharmacokinetics
Library Call Number Additional Info Location Last
NTIS  PB90-245788 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 6p
In 1977 and 1985, serum polychlorinated biphenyl (PCB) concentrations were determined for 58 workers in a Bloomington, Indiana, factory that used PCBs in capacitor manufacture until 1977. Less chlorinated PCBs were quantitated as Aroclor 1242, and more highly chlorinated PCBsw were quantitated as Aroclor 1254. The median half-life was 2.6 y for Aroclor 1242 and 4.8 y for Aroclor 1254. However, the half-life varied inversely with the initial serum concentration. This pattern may be a result of continued low-level exposure, variation in the time of exposure, or enzyme induction by PCBs.