Record Display for the EPA National Library Catalog


Main Title Evaluation of Reverse Phase Liquid Chromatography/Mass Spectrometry for Estimation of N-Octanol/Water Partition Coefficients for Organic Chemicals.
Author Burkhard, L. P. ; Kuehl, D. W. ; Veith, G. D. ;
CORP Author Environmental Research Lab.-Duluth, MN. ;Wisconsin Univ.-Superior. Center for Lake Superior Environmental Studies.
Year Published 1985
Report Number EPA/600/J-85/450;
Stock Number PB87-116398
Additional Subjects Chemical analysis ; Mass spectroscopy ; Chromatographic analysis ; Reprints ; High pressure liquid chromatography ; Octanol
Library Call Number Additional Info Location Last
NTIS  PB87-116398 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
A reverse-phase high pressure liquid chromatography/mass spectrometry (HPLC/MS) method was developed for estimating n-octanol/water partition coefficients (K sub ow) of anthropogenic molecules in complex chemical mixtures (e.g., complex effluents and solid waste leachates). The average error for an estimated log K sub ow was ca.0.5 and this error was similar for both aliphatic and aromatic compounds. The minimum level of detection using the total ion current profile generally decreased with increasing molecular weight between 100 and 600 daltons. Results obtained demonstrate that the HPLC/MS method is a viable technique for estimating log K sub ow's of anthropogenic chemicals in complex environmental samples.