Record Display for the EPA National Library Catalog


Main Title Research Towards Developing Methods for Selected Pharmaceutical and Personal Care Products (PPCPs) Adapted for Biosolids.
Author Jones-Lepp, T. L. ; Osemwengie, L. ; Brumley, W. C. ;
CORP Author Environmental Protection Agency, Las Vegas, NV. National Exposure Research Lab.
Publisher Sep 2006
Year Published 2006
Report Number EPA/600/X-06/017 ;NERL-LV-ESD-06-159;
Stock Number PB2006-115550
Additional Subjects Biosolids ; Pharmaceuticals ; Personal care products ; Research and development ; Waste treatment ; Detection ; Quantification ; Waste management ; Contaminants ; Sewage sludge ; Water pollution ; Extraction ; Exposure ; Analytical methods ; Gas chromatography ; Mass spectrometry ; Antibotics ; Macrolides ; Fluoroquinolones ; Methodology ;
Library Call Number Additional Info Location Last
NTIS  PB2006-115550 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 44p
The research presented in this report is a compilation of methods for the detection and quantification of specific PPCPs (i.e., antibiotics: macrolides and fluoroquinolones, and synthetic musks) in biosolids. PPCPs are part of waste streams entering sewage treatment plants, and may concentrate in biosolids. Starting with previously developed analytical methods for these compounds in wastewater, various extraction and detection techniques were carried out to determine the most efficient methodologies. The objective was to improve the sensitivity and recovery for these compounds from Class A biosolids. For all analytes a pressurized liquid extraction (PLE) technique was adopted. Detection was achieved with gas chromatography-mass spectrometry (GC-MS) for the synthetic musks. High performance liquid chromatography (HPLC) coupled with diode array detection (DAD) or electrospray-ion trap mass spectroscopy (ESI-ITMS) were chosen as detection techniques for the antibiotics.