This paper is meant to be an updated reference for project managers, engineers, students, and others interested in a review of case studies of the instances where permeable reactive barriers have been used to remediate sites contaminated with inorganics and radionuclides. This paper mainly focuses on case studies, but a brief overview will be given on topics such as: treatment media types, reactive processes, site characterization, configuration, and the nature of contamination. The case studies are broken into two sections-inorganics and radionuclides- and are listed alphabetically within each section. They contain the most recent information available, as well as contact information for future updates. A section highlighting upcoming research followed by a lessons learned section and a section focusing on the future directions of PRB technology are also included at the end of the paper.