Record Display for the EPA National Library Catalog


Main Title Responses of Subjects with Chronic Obstructive Pulmonary Disease after Exposures to 0.3 PPM Ozone.
Author Kehrl, H. R. ; Hazucha, M. J. ; Solic, J. J. ; Bromberg, P. A. ;
CORP Author North Carolina Univ. at Chapel Hill. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA-R-807392; EPA/600/J-85/084;
Stock Number PB85-237675
Additional Subjects Ozone ; Toxicology ; Respiratory diseases ; Responses ; Exposure ; Smoking ; Exercise(Physiology) ; Reprints ; Air pollution effects(Humans) ; Chronic obstructive lung disease
Library Call Number Additional Info Location Last
NTIS  PB85-237675 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
The authors previously reported (1982) that the respiratory mechanics of intermittently exercising persons with chronic obstructive pulmonary disease (COPD) were unaffected by a 2-h exposure to 0.2 ppm ozone. Employing a single-blind cross-over design protocol, 13 white men with nonreversible COPD were randomly exposed on two consecutive days for 2 h to air and 0.3 ppm ozone. During exposures, subjects exercised for 7.5 min every 30 min; ventilation and gas exchange measured during exercise showed no difference between exposure days. Pulmonary function tests (spirometry, body plethysmography) obtained before and after exposures were unchanged on the air day.