Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 9

OLS Field Name OLS Field Data
Main Title Movement of Mercury in Rat Submaxillary Slices.
Author Smith, Ladd W. ; Borzelleca, Joseph F. ;
CORP Author Medical Coll. of Virginia, Richmond. Dept. of Pharmacology.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1980
Report Number EPA-R-804318; EPA-600/J-80-339;
Stock Number PB82-118191
Additional Subjects Mercury(Metal) ; Nitrogen ; Inhibitors ; Rats ; Tissues(Biology) ; Concentration(Composition) ; Metals ; Pathology ; Reprints ; Submandibular gland
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB82-118191 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Abstract
The movement of HgCl2 was studied in slices of rat submaxillary gland. A steady-state distribution was reached within 60 min. N2 or metabolic inhibitors failed to decrease tissue uptake. Increasing the concentration of Hg2+ produced a corresponding increase in tissue metal. Decreasing the incubation temperature decreased uptake. Cd2+ and Fe2+ decreased uptake but Zn2+, Cu2+, and Fe3+ were without effect. Efflux experiments indicated a firm binding of Hg2+. The data suggest a passive uptake for Hg2+ with unsaturable, temperature-sensitive binding sites in the interior of the cell.