Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Acute Toxicity of Monochlorophenols, Dichlorophenols and Pentachlorophenol in the Mouse.
Author Borzelleca, J. F. ; Hayes, J. R. ; Condie, L. W. ; Egle, J. L. ;
CORP Author Medical Coll. of Virginia, Richmond. Dept. of Pharmacology and Toxicology.;Health Effects Research Lab., Cincinnati, OH.
Year Published 1985
Report Number EPA-R-808861; EPA/600/J-85/352;
Stock Number PB86-175478
Additional Subjects Toxicity ; Phenols ; Bioassay ; Mice ; Laboratory animals ; Dosage ; Chlorine organic compounds ; Reprints ; Phenol/dichloro ; Phenol/monochloro ; Phenol/pentachloro
Library Call Number Additional Info Location Last
NTIS  PB86-175478 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 6p
Acute oral LD50 values were determined for 2-, 3-, and 4-chlorophenol; 2,3-, 2,4-, 2,5-, 2,6-, 3,4-, and 3,5 dichlorophenol and pentachlorophenol in male and female mice. LD50 values (mg/kg) ranged from 117 (females) and 177 (males) for pentachlorophenol to 2389 (females) and 2643 (males) for 3,5-dichlorophenol. It was found that 2-chlorophenol and 3-chlorophenol were considerably more toxic than the dichlorophenol series. Values for males and females were generally similar, the major differences being with pentachlorophenol and 2,5-dichlorophenol where in both cases the female LD50 was lower.