Record Display for the EPA National Library Catalog


Main Title Are There Carcinogens in Water for Human Consumption. An Epidemiologist's Viewpoint.
Author Chiu, A. O. S. ; Bayliss, D. L. ; Wang, R. G. M. ;
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher 1994
Year Published 1994
Report Number EPA/600/A-94/112 ;OHEA-C-564;
Stock Number PB94-190600
Additional Subjects Drinking water ; Carcinogenesis ; Epidemiology ; Risk assessment ; Environmental exposure ; Health status ; Oncogenes ; Cancer ; Humans ; Public health ; Water pollution effects(Humans) ; Sources ; Dosage ; Reprints ; MCL(Maximum contamination level)
Library Call Number Additional Info Location Last
NTIS  PB94-190600 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 19p
Carcinogenesis is a complex and dynamic interaction of host and environment. Important host factors include genetic constitution and health status. Among environmental factors, diet, pollutants in air and water, occupation, and life-style characteristics, such as smoking, are known to affect cancer development in the human population. This perspective represents a synthesis of the accumulated knowledge from epidemiology and animal experiments. Cancer epidemiology, in contrast to animal toxicological studies, requires no transference of the conclusions from the analysis of the animal data to indicate human carcinogenic potential. The long latency between the inception of cancer and its manifestation, and comparatively low incidence in human beings, as well as the difficulty of ascertaining exposure, have made an epidemiological approach demonstrating a cause-and-effect relationship between the suspected carcinogen and a specific cancer a very difficult if not impossible task. The recent flurry of activity in basic research in oncogenes also reinforces Knudson and others observations regarding genetic influences on cancer development.