Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Pesticide Residue Analysis in Human Tissue by Combined Gas Chromatography-Mass Spectrometry.
Author Biros, Francis J. ; Walker., Annita C. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1970
Stock Number PB-275 500
Additional Subjects Pesticides ; Chemical analysis ; Gas chromatography ; Mass spectrometry ; Residues ; Humans ; Tissue extracts ; Chlorine organic compounds ; DDT ; Dieldrin ; Reprints ; Cyclohexane/hexachloro ; Lindane
Library Call Number Additional Info Location Last
NTIS  PB-275 500 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 5p
Pesticide residues in human adipose tissue and liver tissue samples were identified by mass spectrometry coupled with gas chromatography. An extensive extraction and cleanup procedure was adapted from existing analytical methods to separate pesticide residues from the tissue samples. Concentration of pesticides in tissue ranged from 0.073 to 28.7 ppm. Mass spectral data were computer-enhanced to identify heptachlor epoxide. Other pesticides confirmed included the beta-isomer of 1,2,3,4,5,6-hexachlorocyclohexane (HCH), several isomers and metabolites of p,p'-DDT, and dieldrin. Advantages, limitations, and suggested modifications for improving the combined gas chromatography-mass spectrometry technique for pesticide residue analysis are discussed.