Record Display for the EPA National Library CatalogRECORD NUMBER: 1 OF 1
|Main Title||Exposure to Parathion, Measurement by Blood Cholinesterase Level and Urinary p-Nitrophenol Excretion.|
|Author||Arterberry, J. D. ; Durham, William F. ; Elliott, Joseph W. ; Wolfe., Homer R. ;|
|CORP Author||Communicable Disease Center, Atlanta, Ga.|
|Stock Number||PB-280 572; PB-280 565|
|Additional Subjects||Pesticides ; Industrial medicine ; Toxicology ; Toxic diseases ; Exposure ; Excretion ; Cholinesterase ; Measurement ; Insecticides ; Tables(Data) ; Nitrophenols ; Signs and symptoms ; Surveys ; Phosphorus organic compounds ; Washington(State) ; Reprints ; Parathion ; Toxic substances ; Occupational safety and health ; Metabolites|
A survey of blood cholinesterase activity and urinary p-nitrophenol excretion of occupational groups exposed to parathion was made in central Washington in 1958. Only the group with the highest potential exposure to parathion (mixing-plant personnel) showed a definite decrease in cholinesterase level during exposure. The enzyme diminution for this group occurred only with the erythrocytes. All 5 of the highest exposure groups (mixing-plant personnel, commercial ground applicators, part-time ground applicators, aircraft application workers, and workers in orchards) excreted significant quantities of p-nitrophenol during the period of their exposure. The excretion of measurable amounts of p-nitrophenol in the presence of normal plasma and red blood cell cholinesterase levels is important as an indication that p-nitrophenol excretion is a more sensitive measure of exposure to parathion than is blood cholinesterase activity. The average p-nitrophenol excretion of the residents-near-orchard group was not significant.
Included in PB-280 565, Journal articles on toxicology. Group 12.