||Physiological response to atmospheric pollutants /
Amdur, Mary O.
||Harvard School of Public Health, Boston, Mass. Dept. of Physiology.;Health Effects Research Lab., Research Triangle Park, N.C.
|| U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
||EPA-600/1-78-021; EPA-R-802030; PB280413
||PB 280 413
Sulfuric acid ;
Sulfur dioxide ;
Physiological effects ;
Respiratory system ;
Guinea pigs ;
Laboratory animals ;
Experimental data ;
Environmental health ;
Air pollution effects(Animals) ;
Toxic substances ;
Air pollution effects(Humans)
||Some EPA libraries have a fiche copy filed under the call number shown.
||v, 35 p. : ill. ; 28 cm.
During the period of this grant several materials were examined as air pollutants of interest for their irritant effects. These included sulfuric acid, a series of inorganic sulfates, and a combination of ozone and sulfur dioxide. Some attention was also given to the effect of various oil mists on the irritant response to sulfur dioxide. The method used for measuring irritant response was by simultaneous tracings of intrapleural pressure, tidal volume, and rate of flow of gas in and out of the respiratory system. By relating the intrapleural pressure change to the change in flow rate at points of equal lung volume, it was possible to calculate the flow resistance; by relating pressure change to volume at the beginning and end of inspiration, it was possible to calculate compliance. The concentrations used in these studies are well within the range of human exposure. These studies indicate that the irritant response previously observed at higher concentrations of sulfuric acid is also observed at concentrations below 1 mg/cu m.
"March 1978". Photocopy. Includes bibliographical references.