||Effects of Continuous-Wave, Pulsed, and Sinusoidal-Amplitude-Modulated Microwaves on Brain Energy Metabolism.
Sanders, A. P. ;
Joines, W. T. ;
Allis, J. W. ;
||Health Effects Research Lab., Research Triangle Park, NC. ;Duke Univ., Durham, NC.
Radiation effects ;
Laboratory animals ;
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A comparison of the effects of continuous wave, sinusoidal-amplitude modulated, and pulsed square-wave-modulated 591-MHz microwave exposures on brain energy metabolism was made in male Sprague Dawley rats (175-225g). Brain NADH fluorescence, adensine triphosphate (ATP) concentration and creatine phosphate (CP) concentration were determined as a function of modulation frequency. Brain temperatures of animals were maintained between -0.1 and -0.4C from the pre-exposure temperature when subjected to as much as 20 mW/sq. cm. (average power) CW, pulsed or sinusoidalamplitude-modulated 591-MHz radiation for 5 minutes. Sinusoidal-amplitude-modulated exposures at 16 to 24 Hz showed a trend toward preferential modulation frequency response in inducing an increase in brain NADH fluorescence. The pulse-modulated and sinusoidal-amplitude-modulated (16 Hz) microwaves were not significantly different from CW exposures in inducing increased brain NADH fluorescence and decreased ATP and CP concentrations.