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Main Title Differential Effects of 200, 591, and 2,450 MHz Radiation on Rat Brain Energy Metabolism.
Author Sanders, A. P. ; Joines, W. T. ; Allis, J. W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Duke Univ., Durham, NC.
Year Published 1984
Report Number EPA/600/J-84/307;
Stock Number PB85-220440
Additional Subjects Radiation effects ; Brain ; Rats ; Laboratory animals ; Energy ; Metabolism ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB85-220440 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 17p
Three key compounds in brain metabolism have been measured during and after exposure to continuous wave radiofrequency radiation at 200, 591, and 2,450 MHz. Frequency-dependent changes have been found for all three compounds. Changes in NADH fluorescence have been measured on the surface of a surgically uncovered rat brain during exposure. At 200 and 591 MHz, NADH fluorescence increased in a dose-dependent manner between approximately 1 and 10 mW/sq. cm., then became constant at higher exposures. There was no effect at 2,450 MHz. Levels of ATP and CP were measured in whole brain after exposure. The ATP levels were decreased at 200 and 591 MHz but not at 2,450 MHz. The CP levels decreased only at 591 MHz. The effect of duration of exposure (up to 5 min) was investigated for all compounds at 200 MHz and 2,450 MHz, and exposures to 20 minutes were examined at 591 MHz. Temperature in the rat brain was essentially constant for all exposures. A general mechanism for inhibition of the mitochondrial electron transport chain and the CP-kinase reaction pathway by radiofrequency radiation has been proposed.