Record Display for the EPA National Library Catalog


Main Title Lethality in Mice and Rats Exposed to 2450 MHz Circularly Polarized Microwaves as a Function of Exposure Duration and Environmental Factors.
Author Berman, E. ; Kinn, J. B. ; Ali, J. ; Carter, H. B. ; Rehnberg, B. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/063;
Stock Number PB85-219707
Additional Subjects Microwaves ; Radiation effects ; Lethal dosage ; Exposure ; Mice ; Rats ; Laboratory animals ; Temperature ; Humidity ; Reprints ; Environmental factors
Library Call Number Additional Info Location Last
NTIS  PB85-219707 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Adult male CD-1 mice and CD rats were used to determine LD50/24 hr of lethality from exposure to 2450-MHz circularly-polarized microwaves. Groups of sixteen mice or six rats were exposed in each of 32 combinations of nominal power density (10, 25, 50 or 75 mW/sq. cm.), exposure duration (1 or 4 hrs), and environmental temperature (20 or 30C) and relative humidity (35 or 80%). An analysis of variance probit model was used to determine the influence each variable had on the probability of death. Significant factors in lethality were nominal power density, exposure duration, and environmental temperature, but not environmental relative humidity. The estimated power density required to kill 50% of the animals in 24 hours is halved when the environmental temperature is increased from 20 to 30C. Similarly, only 20-25% of the power density is required when the exposure duration is increased from one to four hours. The use of nominal power density as a predictor of the probability of death was more efficient than specific absorption rate estimated experimentally by twin-well calorimetry. The exposure of one mouse at a time, instead of 16, did not alter the predicted death rate.