Record Display for the EPA National Library Catalog


Main Title Reproducibility of Individual Responses to Ozone Exposure.
Author McDonnell, W. F. ; Horstman, D. H. ; Abdul-Salaam, S. ; House, D. E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/012;
Stock Number PB85-198323
Additional Subjects Ozone ; Toxicology ; Exposure ; Concentration ; Signs and symptoms ; Respiratory system ; Reprints ; Air pollution effects(Humans)
Library Call Number Additional Info Location Last
NTIS  PB85-198323 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Because large intersubject differences in the magnitudes of response to a single ozone (03) exposure have been observed, the authors undertook to determine if this variability were due to differences in intrinsic responsiveness to 03 or to other factors. Each of thirty-two subjects was exposed to one of five 03 concentrations (0.12, 0.18, 0.24, 0.30, or 0.40 ppm), and each underwent one or more repeat exposures. Separated by from 3 weeks to 14 months. Magnitudes of change for pulmonary function and respiratory timing variables and for reported symptoms were compared for the repeated exposures. Changes induced in forced expiratory spirometric measurements were highly reproducible for up to 10 months and for all tested 03 concentrations 0.18 ppm.