Grantee Research Project Results
Selected Publications Details for Grant Number R829388C001
Environmental Factors in the Etiology of Autism; Analytic Biomakers (xenobiotic) Core
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Centers for Children's Environmental Health and Disease Prevention Research (2001)
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Book Chapter | Immunoassay, biosensors and other nonchromatographic methods. | None | Shan G, Lipton C, Gee SJ, Hammock BD | Shan G, Lipton C, Gee SJ, Hammock BD. Immunoassay, biosensors and other nonchromatographic methods. In: Lee PW, ed. Handbook of Residue Analytical Methods for Agrochemicals, Volume 2. Chichester, UK: John Wiley and Sons, Ltd., 2002, pp. 623-679. |
R825433 (Final) R829388 (2006) R829388 (Final) R829388C001 (2003) R829388C001 (2005) |
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Journal Article | Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene and kinoprene at trace levels using Diels-Alder derivatization. | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | Aronov PA, Dettmer K, Christiansen JA, Cornel AJ, Hammock BD | Aronov PA, Dettmer K, Hammock BD, Christiansen JA, Cornel AJ. Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene, and kinoprene at trace levels using Diels-Alder derivatization. Journal of Agricultural and Food Chemistry 2005;53(9):3306-3312. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD, Weiss RH | Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD, Weiss RH. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2222-2227. |
R829388 (2006) R829388 (Final) R829388C001 (2002) R829388C001 (2005) |
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Journal Article | Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. | OBESITY RESEARCH | Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD | Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obesity Research 2004;12(8):1278-1289. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. | AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY | Fang X, Weintraub NL, Oltman CL, Stoll LL, Kaduce TL, Harmon S, Dellsperger KC, Morisseau C, Hammock BD, Spector AA | Fang X, Weintraub NL, Oltman CL, Stoll LL, Kaduce TL, Harmon S, Dellsperger KC, Morisseau C, Hammock BD, Spector AA. Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide. American Journal of Physiology-Heart and Circulatory Physiology 2002;283(6):H2306-H2314. |
R829388 (2006) R829388 (Final) R829388C001 (2003) R829388C001 (2005) |
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Journal Article | Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. | AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY | Fang X, Weintraub NL, McCaw RB, Hu S, Harmon SD, Rice JB, Hammock BD, Spector AA | Fang X, Weintraub NL, McCaw RB, Hu S, Harmon SD, Rice JB, Hammock BD, Spector AA. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. American Journal of Physiology-Heart and Circulatory Physiology 2004;287(6):H2412-H2420. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Mercury methylation from unexpected sources: molybdate-inhibited freshwater sediments and an iron-reducing bacterium. | APPLIED AND ENVIRONMENTAL MICROBIOLOGY | Fleming EJ, Mack EE, Green PG, Nelson DC | Fleming EJ, Mack EE, Green PG, Nelson DC. Mercury methylation from unexpected sources: molybdate-inhibited freshwater sediments and an iron-reducing bacterium. Applied and Environmental Microbiology 2006;72(1):457-464. |
R828676C003 (2004) R829388 (Final) R829388C001 (2005) |
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Journal Article | Metabolomics in practice: emerging knowledge to guide future dietetic advice toward individualized health. | JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION | German JB, Watkins SM, Fay LB | German JB, Watkins SM, Fay LB. Metabolomics in practice: emerging knowledge to guide future dietetic advice toward individualized health. Journal of the American Dietetic Association 2005;105(9):1425-1432. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Metabolomics in human nutrition: opportunities and challenges. | THE AMERICAN JOURNAL OF CLINICAL NUTRITION | Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B | Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B. Metabolomics in human nutrition: opportunities and challenges. American Journal of Clinical Nutrition 2005;82(3):497-503. |
R829388 (2006) R829388 (Final) R829388C001 (2005) R833292 (Final) |
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Journal Article | Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. | CHEMICAL RESEARCH IN TOXICOLOGY | Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD | Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chemical Research in Toxicology 2005;18(3):516-527. |
R829388 (Final) R829388C001 (2005) |
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Journal Article | Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. | TOXICON | Inceoglu B, Lango J, Pessah IN, Hammock BD | Inceoglu B, Lango J, Pessah IN, Hammock BD. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon 2005;45(6):727-733. |
R829388 (Final) R829388C001 (2005) |
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Journal Article | Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. | JOURNAL OF MEDICINAL CHEMISTRY | Kim IH, Morisseau C, Watanabe T, Hammock BD | Kim I-H, Morisseau C, Watanabe T, Hammock BD. Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. Journal of Medicinal Chemistry 2004;47(8):2110-2122. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. | JOURNAL OF MEDICINAL CHEMISTRY | Kim I-H, Heirtzler FR, Morisseau C, Nishi K, Tsai H-J, Hammock BD | Kim I-H, Heirtzler FR, Morisseau C, Nishi K, Tsai H-J, Hammock BD. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. Journal of Medicinal Chemistry 2005;48(10):3621-3629. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. | JOURNAL OF LIPID RESEARCH | Newman JW, Watanabe T, Hammock BD | Newman JW, Watanabe T, Hammock BD. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. Journal of Lipid Research 2002;43(9):1563-1578. |
R829388 (2006) R829388 (Final) R829388C001 (2003) R829388C001 (2005) |
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Journal Article | The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | Newman JW, Morisseau C, Harris TR, Hammock BD | Newman JW, Morisseau C, Harris TR, Hammock BD. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1558-1563. |
R829388 (2006) R829388 (Final) R829388C001 (2003) R829388C001 (2005) |
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Journal Article | Epoxide hydrolases: their roles and interactions with lipid metabolism. | PROGRESS IN LIPID RESEARCH | Newman JW, Morisseau C, Hammock BD | Newman JW, Morisseau C, Hammock BD. Epoxide hydrolases: their roles and interactions with lipid metabolism. Progress in Lipid Research 2005;44(1):1-51. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma SJ, Hammock BD | Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma SJ, Hammock BD. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2186-2191. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. | JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION | Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B | Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. Journal of the American College of Nutrition 2003;22(6):502-510. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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Journal Article | Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. | JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | Zhao X, Yamamoto T, Newman JW, Kim I-H, Watanabe T, Hammock BD, Stewart J, Pollock JS, Pollock DM, Imig JD | Zhao X, Yamamoto T, Newman JW, Kim I-H, Watanabe T, Hammock BD, Stewart J, Pollock JS, Pollock DM, Imig JD. Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. Journal of the American Society of Nephrology 2004;15(5):1244-1253. |
R829388 (2006) R829388 (Final) R829388C001 (2005) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.