TY - CHAP A1 - Swat, M H A1 - Thomas, G L A1 - Belmonte, J M A1 - Shirinifard, A A1 - Hmeljak, D A1 - Glazier, J A T1 - Multi-scale modeling of tissues using CompuCell3D. Y1 - 2012// N1 - R835001 JF - METHODS IN CELL BIOLOGY J1 - METHOD CELL BIOL VL - 110 SP - 325 EP - 366 ER - TY - JOUR A1 - Andasari, V A1 - Roper, R T A1 - Swat, M H A1 - Chaplain, MA J T1 - Integrating intracellular dynamics using CompuCell3D and BioNetSolver: applications to multiscale modelling of cancer cell growth and invasion. Y1 - 2012/03/ N1 - R835001 JF - PLOS ONE J1 - PLOS One VL - 7 IS - 3 SP - e33726 ER - TY - JOUR A1 - Petersen, B K A1 - Ropella, G A1 - Hunt, C A T1 - Toward modular biological models: defining analog modules based on referent physiological mechanisms. Y1 - 2014/08/16 N1 - R835001 VL - 8 SP - 95 ER - TY - JOUR A1 - Sluka, J P A1 - Glazier, J A A1 - Swat, M T1 - Infrastructure requirements for moving multiscale modeling from research tools to the clinical and regulatory domains. Y1 - 2012/01/ N1 - R835001 VL - 7 SP - 12 ER - TY - JOUR A1 - Sluka, J A1 - Shirinifard, A A1 - Swat, M A1 - Cosmanescu, A A1 - Heiland, R W A1 - Glazier, J T1 - The Cell Behavior Ontology: describing the intrinsic biological behaviors of real and model cells seen as active agents. Y1 - 2014/08/15 N1 - R835001 VL - 30 IS - 16 SP - 2367 EP - 2374 ER - TY - JOUR A1 - Wambaugh, J F A1 - Wetmore, B A A1 - Pearce, R A1 - Strope, C A1 - Goldsmith, R A1 - Sluka, J P A1 - Sedykh, A A1 - Tropsha, A A1 - Bosgra, S A1 - Shah, I A1 - Judson, R A1 - Thomas, R S A1 - Setzer, R W T1 - Toxicokinetic triage for environmental chemicals. Y1 - 2015/09/ N1 - R835001 N1 - R835166 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 147 IS - 1 SP - 55 EP - 67 ER - TY - JOUR A1 - Wang, Y A1 - Lin, Z A1 - Liu, Z A1 - Harris, S A1 - Kelly, R A1 - Zhang, J A1 - Ge, W A1 - Chen, M A1 - Borlak, J A1 - Tong, W T1 - A unifying ontology to integrate histological and clinical observations for drug-induced liver injury. Y1 - 2013/04/ N1 - R835001 JF - AMERICAN JOURNAL OF PATHOLOGY J1 - AM J PATHOL VL - 182 IS - 4 SP - 1180 EP - 1187 ER - TY - CONF A1 - Belmonte, J A1 - Fu, X A1 - Sluka, J P A1 - Swat, M A1 - Glazier, J A T1 - Blood flow and oxygen distribution in a simulated 3D liver lobule. Y1 - 2013/09/ N1 - R835001 ER - TY - CONF A1 - Fu, X T1 - Flow modeling in simulated liver lobule. Y1 - 2014/06/15-19 N1 - R835001 ER - TY - CONF A1 - Fu, X T1 - A simulation framework for modeling acetaminophen induced liver toxicity. Y1 - 2014/06/25 N1 - R835001 ER - TY - CONF A1 - Glazier, J A T1 - [Presentation]. Y1 - 2011/08/28-1 N1 - R835001 ER - TY - CONF A1 - Glazier, J A A1 - Swat, M A1 - Sluka, J P T1 - Challenges for multi-scale virtual tissues: where we are and where we need to go: computational component libraries and biological component libraries. Y1 - 2014/09/3-4 N1 - R835001 ER - TY - CONF A1 - Glazier, J T1 - From molecules to tissues: multiscale modeling from a multicellular viewpoint. Y1 - 2012/12/13-14 N1 - R835001 ER - TY - CONF A1 - Hunt, C A A1 - Ropella, G A1 - Smith, A T1 - Explanatory, concrete insight Into location-dependent, multiscale aspects of APAP-induced liver injury. Y1 - 2013/09/ N1 - R835001 ER - TY - CONF A1 - Ropella, G A1 - Petersen, B A1 - Hunt, C A T1 - Exploring two modularity techniques for agent-based models. Y1 - 2014/09/3-4 N1 - R835001 ER - TY - CONF A1 - Sluka, J P A1 - Cosmanescu, A A1 - Swat, M A1 - Glazier, J A T1 - From macro to micro dosimetry, pharmacology and toxicity: a multiscale modeling framework of xenobiotics using open source tools. Y1 - 2012/09/ N1 - R835001 ER - TY - CONF A1 - Sluka, J P A1 - Fu, X A1 - Swat, M A1 - Glazier, J A T1 - Parameter sensitivities in a multiscale model of acetaminophen metabolism: from whole-body to subcellular reaction kinetics. Y1 - 2014/09/3-4 N1 - R835001 ER - TY - CONF A1 - Sluka, J T1 - Optimizing model specification in cross-scale computational biology. Y1 - 2012/12/13-14 N1 - R835001 ER - TY - CONF A1 - Sluka, J A1 - Fu, X A1 - Belmonte, J A1 - Cosmanescu, A A1 - Swat, M A1 - Glazier, J A T1 - A multiscale in silica modeling framework of xenobiotics. Y1 - 2014/03/23-27 N1 - R835001 ER - TY - CONF A1 - Smith, A A1 - Ropella, G A1 - Hunt, C A T1 - Explaining complex phenomena by discovering, validating, and falsifying in silico mechanistic hypotheses: a demonstration focused on multiple features of acetaminophen hepatotoxicity. Y1 - 2014/09/3-4 N1 - R835001 ER - TY - CONF A1 - Swat, M T1 - Multicell modelling using CompuCell3D. Y1 - 2012/12/13-14 N1 - R835001 ER - TY - CONF A1 - Wambaugh, J A1 - Strope, C A1 - Nicolas, C A1 - Pearce, R A1 - Judson, R A1 - Goldsmith, R A1 - El-Masri, H A1 - Wetmore, B A1 - Sluka, J A1 - Tropsha, A A1 - Bosgra, S A1 - Shah, I A1 - Thomas, R A1 - Setzer, R W T1 - High throughput pharmacokinetics for environmental chemicals. Y1 - 2014/03/23-27 N1 - R835001 ER - TY - CONF A1 - Heiland, R A1 - Swat, M A1 - Sluka, J A1 - Zaitlen, B A1 - Shirinifard, A A1 - Thomas, G A1 - Lumsdaine, A A1 - Glazier, J T1 - Visualizing cells and their connectivity graphs for CompuCell3D. Y1 - 2012/10/14-19 N1 - R835001 SP - 85 EP - 90 ER - TY - CONF A1 - Smith, A A1 - Ropella, G A1 - Kaplowitz, N A1 - Ookhtens, M A1 - Hunt, C A T1 - Mechanistic agent-based damage and repair models as hypotheses for patterns of necrosis caused by drug induced liver injury. Y1 - 2014// N1 - R835001 ER -