TY - Abstract
A1 - Kousba, A
A1 - Poet, T S
A1 - Timchalk, C
T1 - Potential utility of saliva biomonitoring for assessing organophosphate insecticide dosimetry and esterase inhibition.
Y1 - 2003//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 72
IS - S-1
SP - 1484
ER -
TY - Abstract
A1 - Kousba, A
A1 - Poet, T S
A1 - Zangar, R
A1 - Timchalk, C
T1 - In vitro interactions between organophosphorus pesticides and consequence of pre-treatment with nicotine and alcohol on in vitro pesticide metabolism in rats.
Y1 - 2004//
N1 - R828608
JF - DRUG METABOLISM REVIEWS
J1 - DRUG METAB REV
ER -
TY - Abstract
A1 - Kousba, A
A1 - Sultatos, L G
A1 - Poet, T S
A1 - Timchalk, C
T1 - Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site.
Y1 - 2004//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 78
IS - 1-S
SP - 2063
ER -
TY - Abstract
A1 - Timchalk, C
A1 - Kousba, A
A1 - Poet, T S
T1 - Assessing the impact of human PON1 polymorphisms: sensitivity and Monte Carlo analyses using a physiologically based pharmacokinetic/ pharmacodynamic (PBPK/PD) model for chlorpyrifos.
Y1 - 2002//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 66
IS - 1-S
SP - 1525
ER -
TY - Abstract
A1 - Timchalk, C
A1 - Kousba, A
A1 - Poet, T S
T1 - Development of a neonatal rat physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for chlorpyrifos.
Y1 - 2003//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 72
IS - S-1
SP - 1483
ER -
TY - Abstract
A1 - Timchalk, C
A1 - Poet, T S
A1 - Hinman, M N
A1 - Busby, A L
A1 - Kousba, A
T1 - Pharmacokinetic and pharmacodynamic interactions of a binary mixture of chlorpyrifos and diazinon in the rat.
Y1 - 2004//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
ER -
TY - Abstract
A1 - Wu, H
A1 - Kousba, A
A1 - Timchalk, C
A1 - Poet, T S
T1 - Hepatic and intestinal CYP450 metabolism of chlorpyrifos.
Y1 - 2002//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 66
IS - 1-S
SP - LB134
ER -
TY - Abstract
A1 - Wu, H
A1 - Timchalk, C
A1 - Kousba, A
A1 - Poet, T S
T1 - Intestinal metabolism of organophosphate insecticides: potential first-pass metabolism.
Y1 - 2003//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 72
IS - S-1
SP - 440
ER -
TY - Abstract
A1 - Wu, H
A1 - Poet, T S
A1 - Timchalk, C
T1 - Inhibition of diazinon metabolism by chlorpyrifos in rat liver microsomes.
Y1 - 2004//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 78
IS - 1-S
ER -
TY - JOUR
A1 - Campbell, J A
A1 - Timchalk, C
A1 - Kousba, A A
A1 - Wu, H
A1 - Valenzuela, B R
A1 - Hoppe, E W
T1 - Negative ion chemical ionization mass spectrometry for the analysis of 3,5,6-trichloro-2-pyridinol in saliva of rats exposed to chlorpyrifos.
Y1 - 2005//
N1 - R828608
JF - ANALYTICAL LETTERS
J1 - ANAL LETT
VL - 38
IS - 6
SP - 939
EP - 949
ER -
TY - JOUR
A1 - Kousba, A A
A1 - Poet, T S
A1 - Timchalk, C
T1 - Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: a potential biomonitoring matrix.
Y1 - 2003//
N1 - R828608
JF - TOXICOLOGY
J1 - TOXICOLOGY
VL - 188
IS - 2-3
SP - 219
EP - 232
ER -
TY - JOUR
A1 - Kousba, A A
A1 - Sultatos, L G
A1 - Poet, T S
A1 - Timchalk, C
T1 - Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site.
Y1 - 2004//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 80
IS - 2
SP - 239
EP - 248
ER -
TY - JOUR
A1 - Poet, T S
A1 - Wu, H
A1 - Kousba, A A
A1 - Timchalk, C
T1 - In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon.
Y1 - 2003//
N1 - R828608
JF - TOXICOLOGICAL SCIENCES
J1 - TOXICOL SCI
J2 - Toxicol.Sci.
J3 - Toxicological Sciences
VL - 72
IS - 2
SP - 193
EP - 200
ER -
TY - JOUR
A1 - Timchalk, C
A1 - Kousba, A
A1 - Poet, T S
T1 - Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model.
Y1 - 2002//
N1 - R828608
JF - TOXICOLOGY LETTERS
J1 - TOXICOL LETT
VL - 135
IS - 1-2
SP - 51
EP - 59
ER -
TY - JOUR
A1 - Timchalk, C
A1 - Poet, T S
A1 - Kousba, A A
A1 - Campbell, J A
A1 - Lin, Y
T1 - Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure: analysis of lead or organophosphate insecticide in saliva.
Y1 - 2004//
N1 - R828608
JF - JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A
J1 - J TOXICOL ENV HEAL A
VL - 67
IS - 8-10
SP - 635
EP - 650
ER -
TY - JOUR
A1 - Timchalk, C
A1 - Poet, T S
A1 - Hinman, M N
A1 - Busby, A L
A1 - Kousba, A A
T1 - Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat.
Y1 - 2005//
N1 - R828608
JF - TOXICOLOGY AND APPLIED PHARMACOLOGY
J1 - TOXICOL APPL PHARM
J2 - Toxicol.Appl.Pharmacol.
J3 - Toxicol Appl Pharmacol
J4 - Toxicology and Applied Pharmacology
VL - 205
IS - 1
SP - 31
EP - 42
ER -
TY - CONF
A1 - Busby, A
A1 - Kousba, A
A1 - Timchalk, C
T1 - The in vivo quantitation of diazinon, chlorpyrifos and their metabolites in rat blood for the refinement of a physiologically–based pharmacokinetic/pharmacodynamic model.
N1 - R828608
ER -
TY - CONF
A1 - Campbell, J A
A1 - Wu, H
A1 - Poet, T S
A1 - Kousba, A A
A1 - Timchalk, C
T1 - Determination of chlorpyrifos and the major metabolite 3,5,6-trichloro-2-pyridinol in blood and saliva of exposed rats.
N1 - R828608
ER -
TY - CONF
A1 - Campbell, J A
A1 - Wu, H
A1 - Poet, T S
A1 - Timchalk, C
T1 - Determination of chlorpyrifos and the major metabolite 3,5,6-trichloro-2-pyridinol in blood and saliva of exposed rats.
N1 - R828608
ER -
TY - CONF
A1 - Kousba, A
A1 - Poet, T
A1 - Timchalk, C
T1 - Comparative study of the kinetic interaction of chlorpyrifos oxon with rat cholinesterase.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Development of a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model to quantitate biomarkers of exposure to organophosphorus insecticides.
Y1 - 2004/06/
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Development of non-invasive biomonitoring approaches and the application of biologically based models to determine dosimetry and risk following chemical exposure.
Y1 - 2004/09/
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Development of physiologically based pharmacokinetic and pharmacodynamic models to determine dosimetry, dynamic response, and assess risk following exposure to organophosphorus insecticides.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
A1 - Kousba, A
A1 - Poet, T S
T1 - A physiologically based pharmacokinetic pharmacodynamic (PBPK/PD) model for chlorpyrifos utilizing neonatal rats as surrogates for children.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Current and future applications of biologically based models for assessing dosimetry and risk (physiologically based models to the virtual organ).
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
A1 - Poet, T S
T1 - Development of a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model to quantitate biomarkers of exposure to organophosphorus insecticides.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Development of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model to quantitate biomarkers of exposure to organophosphate insecticides.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
A1 - Lin, Y
T1 - Development of non-invasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure: analysis of lead and organophosphate insecticide in saliva.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
A1 - Lin, Y
A1 - Kousba, A
A1 - Poet, T S
T1 - Development of pharmacokinetic and non-invasive biomonitoring approaches to determine dosimetry and assess risk in potentially sensitive sub-populations following exposure to individual chemicals and mixtures.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - PBPK/PD modeling of organophosphate (OP) pesticide mixtures.
N1 - R828608
ER -
TY - CONF
A1 - Wu, H
A1 - Weitz, K
A1 - Timchalk, C
A1 - Poet, T S
T1 - Hepatic and intestinal A-esterase metabolism of chlorpyrifos-oxon and diazinon-oxon.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
A1 - Poet, T S
T1 - Development of a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model to quantitate biomarkers of exposure to organophosphorus insecticides.
N1 - R828608
ER -
TY - CONF
A1 - Timchalk, C
T1 - Development of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model to quantitate biomarkers of exposure to organophosphate insecticides.
N1 - R828608
ER -