TY - JOUR A1 - Coles, B A1 - Nowell, S A A1 - MacLeod, S L A1 - Sweeney, C A1 - Lang, N P A1 - Kadlubar, F F T1 - The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk. Y1 - 2001// N1 - R825280 JF - MUTATION RESEARCH J1 - MUTAT RES VL - 482 IS - 1-2 SP - 3 EP - 10 ER - TY - JOUR A1 - Dingley, K H A1 - Curtis, K D A1 - Nowell, S A1 - Felton, J S A1 - Lang, N P A1 - Turteltaub, K W T1 - DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Y1 - 1999// N1 - R825280 JF - CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION VL - 8 IS - 6 SP - 507 EP - 512 ER - TY - JOUR A1 - Frame, L T A1 - Ozawa, S A1 - Nowell, S A A1 - Chou, H A1 - DeLongchamp, R R A1 - Doerge, D R A1 - Lang, N P A1 - Kadlubar, F F T1 - A simple colorimetric assay for phenotyping the major human thermostable phenol sulfotransferase (SULT1A1) using platelet cytosols. Y1 - 2000// N1 - R825280 JF - DRUG METABOLISM AND DISPOSITION J1 - DRUG METAB DISPOS VL - 28 IS - 9 SP - 1063 EP - 1068 ER - TY - JOUR A1 - Lang, N P A1 - Nowell, S A1 - Malfatti, M A A1 - Kulp, K S A1 - Knize, M G A1 - Davis, C A1 - Massengill, J A1 - Williams, S A1 - MacLeod, S A1 - Dingley, K H A1 - Felton, J S A1 - Turteltaub, K W T1 - In vivo human metabolism of [2-C-14]2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) Y1 - 1999// N1 - R825280 JF - CANCER LETTERS J1 - CANCER LETT VL - 143 IS - 2 SP - 135 EP - 138 ER - TY - JOUR A1 - MacLeod, S L A1 - Nowell, S A1 - Massengill, J A1 - Jazieh, A A1 - McClure, G A1 - Plaxco, J A1 - Kadlubar, F F A1 - Lang, N P T1 - Cancer therapy and polymorphisms of cytochromes P450. Y1 - 2000// N1 - R825280 JF - CLINICAL CHEMISTRY AND LABORATORY MEDICINE J1 - CLIN CHEM LAB MED VL - 38 IS - 9 SP - 883 EP - 887 ER - TY - JOUR A1 - Malfatti, M A A1 - Kulp, K S A1 - Knize, M G A1 - Davis, C A1 - Massengill, J P A1 - Williams, S A1 - Nowell, S A1 - MacLeod, S A1 - Dingley, K H A1 - Turteltaub, K W A1 - Lang, N P A1 - Felton, J S T1 - The identification of [2-C-14]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in humans Y1 - 1999// N1 - R825280 JF - CARCINOGENESIS J1 - CARCINOGENESIS VL - 20 IS - 4 SP - 705 EP - 713 ER - TY - JOUR A1 - Nowell, S A A1 - Massengill, J S A1 - Williams, S A1 - Radominska-Pandya, A A1 - Tephly, T R A1 - Cheng, Z Q A1 - Strassburg, C P A1 - Tukey, R H A1 - MacLeod, S L A1 - Lang, N P A1 - Kadlubar, F F T1 - Glucuronidation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved Y1 - 1999// N1 - R825280 JF - CARCINOGENESIS J1 - CARCINOGENESIS VL - 20 IS - 6 SP - 1107 EP - 1114 ER - TY - JOUR A1 - Nowell, S A1 - Ambrosone, C B A1 - MacLeod, S L A1 - Williams, S A1 - Mrackova, G A1 - Plaxco, J A1 - Ozawa, S A1 - Kadlubar, F F A1 - Lang, N P T1 - Relationship of phenol sulfotransferase (SULT1A1) genotype to sulfotransferase activity phenotype in platelet cytosol Y1 - 2000// N1 - R825280 JF - PHARMACOGENETICS J1 - PHARMACOGENETICS ER - TY - JOUR A1 - Ozawa, S A1 - Tang, Y M A1 - Yamazoe, Y A1 - Kato, R A1 - Lang, N P A1 - Kadlubar, F F T1 - Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines. Y1 - 1998/02/ N1 - R825280 JF - CHEMICO-BIOLOGICAL INTERACTIONS J1 - CHEM-BIOL INTERACT VL - 109 IS - 1-3 SP - 237 EP - 248 ER - TY - JOUR A1 - Turteltaub, K W A1 - Dingley, K H A1 - Curtis, K D A1 - Malfatti, M A A1 - Turesky, R J A1 - Garner, R C A1 - Felton, J S A1 - Lang, N P T1 - Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses Y1 - 1999// N1 - R825280 JF - CANCER LETTERS J1 - CANCER LETT PB - Cancer Letter Publications ER - TY - CONF A1 - Lang, N P T1 - Colon cancer from etiology to prevention. N1 - R825280 ER - TY - CONF A1 - DeLongchamp, R R A1 - Kadlubar, F F A1 - Lang, N P T1 - Statistical methods for density estimation applied to NAT2 activities from an Arkansas population. N1 - R825280 ER - TY - CONF A1 - Felton, J S A1 - Knize, M G A1 - Malfatti, M A A1 - Salmon, C P A1 - Kulp, K S A1 - Dingley, K A1 - Lang, N P A1 - Turteltaub, K W T1 - Methods for the determination of carcinogens/mutagens in the diet and applications to risk assessment. N1 - R825280 ER - TY - CONF A1 - Frame, L T A1 - Chou, H A1 - Gatlin, T L A1 - Kadlubar, F F A1 - Nowell, S A1 - Lang, N T1 - Thermostable phenolsulfotransferase (TS-PST) phenotype as a potential risk factor for colon cancer in a case-control study. N1 - R825280 ER - TY - CONF A1 - MacLeod, S L A1 - Nowell, S A A1 - Tang, Y M A1 - Kadlubar, F F A1 - Lang, N P T1 - CYP1B1 polymorphism in colorectal cancer N1 - R825280 ER - TY - CONF A1 - MacLeod, S L A1 - Tang, A1 - Y-M, A1 - Yokoi, T A1 - Kamataki, T A1 - Doublin, S A1 - Lawson, B A1 - Massengill, J A1 - Kadlubar, F F A1 - Lang, N T1 - The role of a recently discovered genetic polymorphism in the regulation of the human CYP1A2 gene. N1 - R825280 ER - TY - CONF A1 - Malfatti, M A A1 - Knize, M G A1 - Kulp, K S A1 - Lawson, B A1 - Davis, C A1 - Massengill, J A1 - Nowell, S A1 - MacLeod, S A1 - Dingley, K A1 - Mauthe, R A1 - Turteltaub, K W A1 - Lang, N P A1 - Felton, J S T1 - The detection of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine metabolites in urine from two colon cancer patients. N1 - R825280 ER - TY - CONF A1 - Malfatti, M A1 - Kulp, K A1 - Knize, M A1 - Davis, C A1 - Massengill, J A1 - Williams, S A1 - Nowell, S A1 - MacLeod, S A1 - Dingley, K A1 - Turteltaub, K A1 - Lang, N A1 - Felton, J T1 - The identification of PhIP metabolites in human urine and blood: a correlation of metabolite profiles and phenotype. N1 - R825280 ER - TY - CONF A1 - Nowell, S A A1 - Massengill, J A1 - Kadlubar, F F A1 - Lang, N P T1 - Glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) By a human recombinant UDP-glucuronosyltransferase. N1 - R825280 ER - TY - CONF A1 - Nowell, S A A1 - Lang, N P A1 - Radominska-Pandya, A A1 - Kadlubar, F F T1 - Glucuronidation of N-hydroxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) by human intestinal microsomes. N1 - R825280 ER - TY - CONF A1 - Nowell, S A A1 - Ozawa, S A1 - Ambrosone, C B A1 - MacLeod, S A1 - Kadlubar, F F A1 - Lang, N P T1 - Relationship of SULT1A1 genotype to sulfotransferase activity phenotype in platelet cytosol: effect of genotype on heterocyclic amine activation. N1 - R825280 ER - TY - CONF A1 - Ozawa, S A1 - Lang, N P A1 - Kadlubar, F F T1 - Genetic polymorphisms in human liver and colon sulfotransferases (SULTs) involved in the bioactivation of carcinogenic N-hydroxy aromatic and heterocyclic amines. N1 - R825280 ER - TY - CONF A1 - Sinha, R A1 - Chow, W H A1 - Kuldorf, M A1 - Denoble, J A1 - Lang, N P A1 - Kadlubar, F F A1 - Hoover, R N A1 - Rothman, N T1 - Well done, grilled red meat, 1-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), metabolizing enzymes, and risk of colorectal adenomas N1 - R825280 ER - TY - CONF A1 - Wang, C A1 - Coles, B A1 - Anderson, K A1 - Lang, N P A1 - Kadlubar, F F T1 - Identification and characterization of a novel polymorphic variant of human alpha-class GSTA2. N1 - R825280 ER -