TY  - Abstract
A1  - Altemeier, W A
A1  - Haick, A 
A1  - Mittelsteadt, K L
A1  - Kavanagh, T J
T1  - Primary mouse airway epithelial cells are resistant to silver nanoparticles.
Y1  - 2016/03/
N1  - R835738C003
N1  - R835738C001
VL  - 150
IS  - Suppl 1
SP  - 10
ER  - 


TY  - Abstract
A1  - Chang, S 
A1  - Voellinger, J L
A1  - White, C 
A1  - Kelly, E J
A1  - Eaton, D L
T1  - A tissue-engineered rat/human liver microphysiological system for drug and chemical testing.
Y1  - 2015/03/
N1  - R835738C003
N1  - R835738
JF  - THE TOXICOLOGIST
VL  - 144
IS  - S-1
SP  - 151
ER  - 


TY  - JOUR
A1  - Chang, S 
A1  - Weber, E J
A1  - Van, N 
A1  - Eaton, D L
A1  - Kelly, E J
T1  - Liver and kidney on chips: micro-physiological models to understand transporter function.
Y1  - 2016/11/
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
JF  - CLINICAL PHARMACOLOGY & THERAPEUTICS
VL  - 100
IS  - 5
SP  - 464
EP  - 478
ER  - 


TY  - JOUR
A1  - Chang, S 
A1  - Weber, E J
A1  - Sidorenko, V S
A1  - Chapron, A 
A1  - Yeung, C K
A1  - Gao, C 
A1  - Mao, Q 
A1  - Shen, D 
A1  - Wang, J 
A1  - Rosenquist, T A
A1  - Dickman, K G
A1  - Neumann, T 
A1  - Grollman, A P
A1  - Kelly, E J
A1  - Himmelfarb, J 
A1  - Eaton, D L
T1  - Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.
Y1  - 2017/11/16
N1  - R835738C003
N1  - R835738C005
VL  - 2004
IS  - 22
SP  - e95978 (15 pp.)
ER  - 


TY  - JOUR
A1  - Chang, S-Y 
A1  - Voellinger, J L
A1  - Van Ness, K P
A1  - Chapron, B 
A1  - Shaffer, R M
A1  - Neumann, T 
A1  - White, C C
A1  - Kavanagh, T J
A1  - Kelly, E J
A1  - Eaton, D L
T1  - Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.
Y1  - 2017/04/
N1  - R835738C003
N1  - R835738C002
N1  - R835738
JF  - TOXICOLOGY IN VITRO
J1  - TOXICOL IN VITRO
VL  - 40
SP  - 170
EP  - 183
ER  - 


TY  - JOUR
A1  - Melnikov, F 
A1  - Botta, D 
A1  - White, C C
A1  - Schmuck, S C
A1  - Schaupp, C M
A1  - Gallagher, E P
A1  - Brooks, B W
A1  - Williams, E S
A1  - Coish, P 
A1  - Anastas, P T
A1  - Voutchkova-Kostal, A 
A1  - Kostal, J 
T1  - Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed in vitro in Mouse Hepatocytes with Enhanced Glutathione Synthesis.
Y1  - 2019/03/
N1  - R835738C003
N1  - R835738C004
N1  - R835738C001
JF  - CHEMICAL RESEARCH IN TOXICOLOGY
J1  - CHEM RES TOXICOL
VL  - 32
IS  - 3
SP  - 421
EP  - 436
ER  - 


TY  - JOUR
A1  - Vernetti, L 
A1  - Gough, A 
A1  - Baetz, N 
A1  - Blutt, S 
A1  - Broughman, J R
A1  - Brown, J A
A1  - Foulke-Abel, J 
A1  - Hasan, N 
A1  - In, J 
A1  - Kelly, E 
A1  - Kovbasnjuk, O 
A1  - Repper, J 
A1  - Senutovitch, N 
A1  - Stabb, J 
A1  - Yeung, C 
A1  - Zachos, N C
A1  - Donowitz, M 
A1  - Estes, M 
A1  - Himmelfarb, J 
A1  - Truskey, G 
A1  - Wikswo, J P
A1  - Taylor, D L
T1  - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle.
Y1  - 2017/02/8
N1  - R835738C003
N1  - R835736C004
N1  - R835736
N1  - R835738C005
N1  - R835738
N1  - R835736C005
JF  - SCIENTIFIC REPORTS
J1  - Scientific Reports
VL  - 7
SP  - 42296 (15 pp.)
ER  - 


TY  - CONF
A1  - Botta, D 
A1  - White, C C
A1  - Melnikov, F 
A1  - Schaupp, C M
A1  - Gallagher, E G
A1  - Brooks, B W
A1  - Kostal, J 
A1  - Voutchkova-Kostal, A M
A1  - Anastas, P T
A1  - Kavanagh, T J
T1  - Using immortalized hepatocytes from wild-type and Gclm knock out mice to investigate the relative toxicity and Nrf2 activation of SN2 reactive electrophiles.
Y1  - 2018/03/11-15
N1  - R835738C003
N1  - R835738
ER  - 


TY  - CONF
A1  - Chang, S Y
A1  - Weber, E 
A1  - Kelly, E J
A1  - Eaton, D L
T1  - Microphysiological systems to identify organ-organ interactions in toxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid.
Y1  - 2015/09/17-18
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - Chang, S Y
A1  - Weber, E 
A1  - Neumann, T 
A1  - Kelly, E J
A1  - Eaton, D L
T1  - Microphysiological Systems (MPS) to identify organ-organ interactions in tToxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid.
Y1  - 2016/03/13-17
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - Eaton, D 
T1  - New frontiers for linked microphysiological systems: integrated liver-kidney systems on a chip.
Y1  - 2017/08/20-24
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - Faustman, E 
A1  - French, E 
A1  - Eaton, D 
A1  - Kelly, E 
A1  - Kavanagh, T 
T1  - Using systems based approaches for refinement, integration and translation.
Y1  - 2017/08/
N1  - R835738C003
N1  - R835738C002
N1  - R835738
N1  - R835738C001
ER  - 


TY  - CONF
A1  - Kavanagh, T J
A1  - Schaupp, C M
A1  - Botta, D 
A1  - Schmuck, S 
A1  - White, C C
A1  - Chisholm, C 
T1  - Measuring chemically-induced oxidative stress in genetically modified cultured mammalian liver cells.
Y1  - 2015/04/23-24
N1  - R835738C003
N1  - R835738
ER  - 


TY  - CONF
A1  - Kavanagh, T 
T1  - Educational tools for designing safer chemicals and predicting toxicity.
Y1  - 2017/08/20-24
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - Kavanagh, T 
T1  - Experiences with collaborative cross for assessing gene X environment interactions for engineered nanomaterials:can we capture human variability in vitro-lessons from the Predictive Toxicology Center.
Y1  - 2017/08/20-24
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - Kelly, E 
T1  - Bioengineered ex vivo models of human organs for predictive toxicity testing.
Y1  - 2017/12/6
N1  - R835738C003
N1  - R835738C005
N1  - R835738C002
N1  - R835738
ER  - 


TY  - CONF
A1  - White, C C
A1  - Botta, D 
A1  - Schaupp, C M
A1  - Kavanagh, T J
T1  - Toxicological assessment of glutathione content, mitochondrial membrane potential and cardiolipin in an immortalized glutathione-deficient mouse hepatocyte cell line.
Y1  - 2017/06/10-14
N1  - R835738C003
N1  - R835738
ER  - 


TY  - CONF
T1  - Initial Characterization of Hepatocytes Derived from Collaborative Cross Recombinant Inbred Mouse Strain iPSCs.
Y1  - 2018//
N1  - R835738C003
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Characterization of Hepatocytes Derived from Collaborative Cross Recombinant Inbred Mouse Strain Induced Pluripotent Stem Cells.
N1  - R835738C003
ER  - 


TY  - CONF
T1  - Role of Interindividual and Genetic Differences in Response of Human and Mouse Hepatocytes to Chemical Stressors.
N1  - R835738C003
ER  -