TY - CHAP
A1 - Van, N
A1 - Kelly, E
T1 - Excretory processes in toxicology: drug transporters in drug development.
Y1 - 2018//
N1 - R835738C002
N1 - R835738
N1 - R835738C001
VL - 1
SP - 143
EP - 164
ER -
TY - JOUR
A1 - Bajaj, P
A1 - Chowdhury, S K
A1 - Yucha, R
A1 - Kelly, E J
A1 - Xiao, G
T1 - Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.
Y1 - 2018/11/
N1 - R835738C002
N1 - R835738C001
JF - DRUG METABOLISM AND DISPOSITION
J1 - DRUG METAB DISPOS
VL - 46
IS - 11
SP - 1692
EP - 1702
ER -
TY - JOUR
A1 - Chang, S
A1 - Weber, E J
A1 - Van, N
A1 - Eaton, D L
A1 - Kelly, E J
T1 - Liver and kidney on chips: micro-physiological models to understand transporter function.
Y1 - 2016/11/
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
JF - CLINICAL PHARMACOLOGY & THERAPEUTICS
VL - 100
IS - 5
SP - 464
EP - 478
ER -
TY - JOUR
A1 - Chang, S
A1 - Weber, E J
A1 - Sidorenko, V S
A1 - Chapron, A
A1 - Yeung, C K
A1 - Gao, C
A1 - Mao, Q
A1 - Shen, D
A1 - Wang, J
A1 - Rosenquist, T A
A1 - Dickman, K G
A1 - Neumann, T
A1 - Grollman, A P
A1 - Kelly, E J
A1 - Himmelfarb, J
A1 - Eaton, D L
T1 - Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.
Y1 - 2017/11/16
N1 - R835738C002
N1 - R835738
VL - 2
IS - 22
SP - 95978 (15 pp.)
ER -
TY - JOUR
A1 - Chang, S-Y
A1 - Voellinger, J L
A1 - Van Ness, K P
A1 - Chapron, B
A1 - Shaffer, R M
A1 - Neumann, T
A1 - White, C C
A1 - Kavanagh, T J
A1 - Kelly, E J
A1 - Eaton, D L
T1 - Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.
Y1 - 2017/04/
N1 - R835738C003
N1 - R835738C002
N1 - R835738
JF - TOXICOLOGY IN VITRO
J1 - TOXICOL IN VITRO
VL - 40
SP - 170
EP - 183
ER -
TY - JOUR
A1 - Monteiro, M B
A1 - Ramm, S
A1 - Chandrasekaran, V
A1 - Boswell, S A
A1 - Weber, E J
A1 - Lidberg, K A
A1 - Kelly, E J
A1 - Vaidya, V S
T1 - A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation.
Y1 - 2018/12/
N1 - R835738C002
N1 - R835738C001
JF - JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
J1 - J AM SOC NEPHROL
VL - 29
IS - 12
SP - 2820
EP - 2833
ER -
TY - JOUR
A1 - Nolin, J D
A1 - Lai, Y
A1 - Ogden, H L
A1 - Manicone, A M
A1 - Murphy, R C
A1 - An, D
A1 - Frevert, C W
A1 - Ghomashchi, F
A1 - Naika, G S
A1 - Gelb, M H
A1 - Gauvreau, G M
A1 - Piliponsky, A M
A1 - Altemeier, W A
A1 - Hallstrand, T S
T1 - Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen.
Y1 - 2017/11/2
N1 - R835738C002
N1 - R835738
N1 - R835738C001
VL - 2
IS - 21
SP - e94929 (18 pp.)
ER -
TY - JOUR
A1 - Sakolish, C
A1 - Weber, E J
A1 - Kelly, E J
A1 - Hummelfarb, J
A1 - Mouneimne, R
A1 - Grimm, F A
A1 - House, J S
A1 - Wade, T
A1 - Chiu, W A
A1 - Rusyn, I
T1 - Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.
Y1 - 2018/09/
N1 - R835738C002
N1 - R835738C001
JF - SCIENTIFIC REPORTS
J1 - Scientific Reports
ER -
TY - JOUR
A1 - Scoville, D K
A1 - Botta, D
A1 - Galdanes, K
A1 - Schmuck, S C
A1 - White, C C
A1 - Stapleton, P L
A1 - Bammler, T K
A1 - MacDonald, J W
A1 - Altemeier, W A
A1 - Hernandez, M
A1 - Kleeberger, S R
A1 - Chen, L C
A1 - Gordon, T
A1 - Kavanagh, T J
T1 - Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice.
Y1 - 2017/10/
N1 - R835738C002
N1 - R835738
N1 - R835738C001
VL - 31
IS - 10
SP - 4600
EP - 4611
ER -
TY - JOUR
A1 - Van Ness, K P
A1 - Chang, S-Y
A1 - Weber, E J
A1 - Zumpano, D
A1 - Eaton, D L
A1 - Kelly, E J
T1 - Microphysiological systems to assess nonclinical toxicity.
Y1 - 2017/08/
N1 - R835738C005
N1 - R835738C002
N1 - R835738C004
N1 - R835738
N1 - R835738C001
VL - 73
IS - 1
SP - 14.18.1
EP - 14.18.28
ER -
TY - JOUR
A1 - Vernetti, L A
A1 - Gough, A
A1 - Baetz, N
A1 - Blutt, S
A1 - Broughman, J R
A1 - Brown
JA,
A1 - Foulke-Abel, J
A1 - Hasan, N
A1 - In, J
A1 - Kelly, E
A1 - Kovbasnjuk, O
A1 - Repper
J,
A1 - Senutovitch, N
A1 - Stabb, J
A1 - Yeung, C
A1 - Zachos, N C
A1 - Donowitz, M
A1 - Estes
M,
A1 - Himmelfarb, J
A1 - Truskey, G
A1 - Wikswo, J P
A1 - Taylor, D
T1 - Functional coupling of human microphysiology systems: intestine, liver,
kidney proximal tubule, blood-brain barrier and skeletal muscle.
Y1 - 2017/02/8
N1 - R835736C004
N1 - R835736
N1 - R835738C005
N1 - R835738C002
VL - 7
SP - 42296 (14 pp.)
ER -
TY - JOUR
A1 - Vernetti, L
A1 - Gough, A
A1 - Baetz, N
A1 - Blutt, S
A1 - Broughman, J R
A1 - Brown, J A
A1 - Foulke-Abel, J
A1 - Hasan, N
A1 - In, J
A1 - Kelly, E
A1 - Kovbasnjuk, O
A1 - Repper, J
A1 - Senutovitch, N
A1 - Stabb, J
A1 - Yeung, C
A1 - Zachos, N C
A1 - Donowitz, M
A1 - Himmelfarb, J
A1 - Truskey, G
A1 - Wikswo, J P
A1 - Taylor, D L
T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle.
Y1 - 2017/02/8
N1 - R835736C004
N1 - R835738C002
N1 - R835738
VL - 7
SP - 42296 (14 pp.)
ER -
TY - JOUR
A1 - Vernetti, L
A1 - Gough, A
A1 - Baetz, N
A1 - Blutt, S
A1 - Broughman, J R
A1 - Brown, J A
A1 - Foulke-Abel, J
A1 - Hasan, N
A1 - In, J
A1 - Kelly, E
A1 - Kovbasnjuk, O
A1 - Repper, J
A1 - Senutovitch, N
A1 - Stabb, J
A1 - Yeung, C
A1 - Zachos, N C
A1 - Donowitz, M
A1 - Himmelfarb, J
A1 - Truskey, G
A1 - Wikswo, J P
A1 - Taylor, D
T1 - Corrigendum: Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle.
Y1 - 2017/03/16
N1 - R835738C005
N1 - R835738C002
N1 - R835738
JF - SCIENTIFIC REPORTS
J1 - Scientific Reports
VL - 7
SP - 44517
ER -
TY - JOUR
A1 - Weber, E J
A1 - Chapron, A
A1 - Chapron, B D
A1 - Voellinger, J L
A1 - Lidberg, K A
A1 - Yeung, C K
A1 - Wang, Z
A1 - Yamaura, Y
A1 - Hailey, D W
A1 - Neumann, T
A1 - Shen, D D
A1 - Thummel, K E
A1 - Muczynski, K A
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Development of a microphysiological model of human kidney proximal tubule function.
Y1 - 2016/09/
N1 - R835738C002
N1 - R835738
JF - KIDNEY INTERNATIONAL
J1 - KIDNEY INT
VL - 90
IS - 3
SP - 627
EP - 637
ER -
TY - JOUR
A1 - Weber, E J
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Concise review: current and emerging biomarkers of nephrotoxicity.
Y1 - 2017/06/
N1 - R835738C002
N1 - R835738
JF - CURRENT OPINION IN TOXICOLOGY
VL - 4
SP - 16
EP - 21
ER -
TY - JOUR
T1 - Excretory Processes in Toxicology:Drug Transporters in Drug Development.
N1 - R835738C002
ER -
TY - JOUR
T1 - Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ. Human Kidney on a Chip Assessment of Polymyxin Antibiotic Nephrotoxicity. JCI Insight 2018;:3(24): e123673.
N1 - R835738C002
VL - 3
IS - 24
SP - e123673
ER -
TY - CONF
A1 - Altemeier, W A
T1 - Development of human organotypic culture systems to model airway biology.
Y1 - 2017/08/21
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Chang, S Y
A1 - Weber, E
A1 - Kelly, E J
A1 - Eaton, D L
T1 - Microphysiological systems to identify organ-organ interactions in toxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid.
Y1 - 2015/09/17-18
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Chang, S Y
A1 - Weber, E
A1 - Neumann, T
A1 - Kelly, E J
A1 - Eaton, D L
T1 - Microphysiological Systems (MPS) to identify organ-organ interactions in tToxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid.
Y1 - 2016/03/13-17
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Eaton, D
T1 - New frontiers for linked microphysiological systems: integrated liver-kidney systems on a chip.
Y1 - 2017/08/20-24
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Faustman, E M
T1 - Testicular cells co-culture as an alternative model for male reproductive toxicity.
Y1 - 017.//
N1 - R835738C002
N1 - R835738C004
N1 - R835738
ER -
TY - CONF
A1 - Faustman, E M
A1 - Kavanagh, T J
A1 - Altemeier, W
A1 - Kelly, E
A1 - Griffith, W C
A1 - Gao, X
A1 - Van Ness, K
A1 - Eaton, D L
T1 - Predictive Toxicology Center for Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials.
Y1 - 2015/03/22-26
N1 - R835738C005
N1 - R835738C002
N1 - R835738C004
N1 - R835738
ER -
TY - CONF
A1 - Faustman, E M
A1 - Kavanagh, T J
A1 - Altemeier, W
A1 - Kelly, E
A1 - Griffith, W C
A1 - Gao, X
A1 - Van Ness, K
A1 - Eaton, D L
T1 - Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials: results from the University of Washington Predictive Toxicology Center (PTC).
Y1 - 2015/11/19-20
N1 - R835738C005
N1 - R835738C002
N1 - R835738C004
N1 - R835738
ER -
TY - CONF
A1 - Faustman, E M
T1 - Systems biology methods for translation of scientific findings across model platforms: identifying normal development versus chemical signals in complex systems.
Y1 - 2017/08/20-24
N1 - R835738C005
N1 - R835738C004
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Faustman, E M
T1 - Using systems biology for linking genes and environment for alcohol research.
Y1 - 2017/06/
N1 - R835738C004
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Faustman, E
A1 - French, E
A1 - Eaton, D
A1 - Kelly, E
A1 - Kavanagh, T
T1 - Using systems based approaches for refinement, integration and translation.
Y1 - 2017/08/
N1 - R835738C003
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Faustman, E
A1 - Weber, E
T1 - MPS-related research.
Y1 - 2017//
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kavanagh, T
T1 - Educational tools for designing safer chemicals and predicting toxicity.
Y1 - 2017/08/20-24
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kavanagh, T
T1 - Experiences with collaborative cross for assessing gene X environment interactions for engineered nanomaterials:can we capture human variability in vitro-lessons from the Predictive Toxicology Center.
Y1 - 2017/08/20-24
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Kidney on a chip: from toxicology to therapeutics.
Y1 - 2015/11/3-8
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Development of a 3D human kidney microphysiological system for drug safety testing.
Y1 - 2015/11/9-11
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing.
Y1 - 2015/10/18-22
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing.
Y1 - 2015/10/27
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - 3D culture system for in vitro nephrotoxicity testing.
Y1 - 2015//
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - The 3 R’s of toxicology and the role of microphysiological systems.
Y1 - 2016/12/13
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Utility of predictive toxicity testing in a 3D microphysiological model of the human kidney proximal tubule.
Y1 - 2016/12/2
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Predictive toxicity testing in a 3D microphysiological model of the human kidney proximal tubule.
Y1 - 2016/10/31
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Organs on chips and reducing the need for animal studies.
Y1 - 2016/09/29-30
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing.
Y1 - 2016//
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Identification and discrimination of cellular responses to new molecular entities utilizing a 3D model of the human kidney proximal tubule.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Predictive toxicity testing in a microphysiological model of the human kidney proximal tubule.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Preclinical approaches for addressing complex human health issues:aristolochic acid nephropathy.
Y1 - 2017/01/6
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Kelly, E J
T1 - Emergent technologies for evaluating drug and xenobiotic disposition.
Y1 - 2017/09/24-28
N1 - R835738C005
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Kelly, E
T1 - Bioengineered ex vivo models of human organs for predictive toxicity testing.
Y1 - 2017/12/6
N1 - R835738C003
N1 - R835738C005
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Klieforth, B
A1 - Shaffer, R M
A1 - mith, M
A1 - Faustman, E M
T1 - Microphysiological system models and the Lautenberg Chemical Safety for the 21st Century Act.
Y1 - 2017/08/20-24
N1 - R835738C005
N1 - R835738C002
N1 - R835738C004
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Lidberg, K A
A1 - Iversen, P L
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Evaluation of antisense oligonucleotide nephrotoxicity using a 3D microphysiological system.
Y1 - 2016/09/29-30
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Nicholas, T
A1 - Haick, A
A1 - Faustman, E
A1 - Altemeier, W A
T1 - Optimization of airway epithelium organotypic culture models as a platform for adverse outcome pathway assessment of engineered nanomaterials.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Nicholas, T
A1 - Haick, A
A1 - Kavanagh, T J
A1 - Faustman, E
A1 - Altemeier, W A
T1 - Optimization of three-dimensional airway epithelium co-culture system as a platform for adverse outcome pathway assessment of engineered nanomaterials.
Y1 - 2017/03/12-16
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -
TY - CONF
A1 - Shaffer, R
A1 - Wilder, C S
A1 - Ryu, C
A1 - Yi, H S
A1 - Park, S Y
A1 - Hong, S
A1 - White, C C
A1 - Workman, T
A1 - Griffith, W C
A1 - Faustman, E M
T1 - Lifestage-specific modeling platform for adverse outcome pathways of male reproductive and developmental processes.
Y1 - 2016/09/29-30
N1 - R835738C005
N1 - R835738C002
N1 - R835738C004
N1 - R835738
ER -
TY - CONF
A1 - Smith, M N
A1 - Shaffer, R M
A1 - Cohen, H
A1 - Faustman, E
T1 - Using in vitro data to compare endocrine disruption potential in hazardous chemicals currently found in children’s products and their proposed alternatives.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van, N
A1 - Weber, E J
A1 - Neumann, T
A1 - Kelly, E J
T1 - Nephrotoxicity of engineered nanoparticles: exposure effects of silver nanoparticles in a kidney microphysiological system.
Y1 - 2016/03/13-17
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van Ness, K P
A1 - Kavanagh, T J
A1 - Kelly, E J
T1 - Microphysiological system assessment of nephrotoxicity of quantum dot with a cadmium/selenium core.
Y1 - 2016/09/29-30
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van Ness, K P
A1 - Kavanagh, T J
A1 - Kelly, E J
T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van Ness, K P
A1 - Kavanagh, T J
A1 - Kelly, E J
T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core.
Y1 - 2017/03/12-16
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van Ness, K P
A1 - Kavanagh, T J
A1 - Kelly, E J
T1 - Microphysiological system assessment of nephrotoxicity of quantum dot with a cadmium/selenium core.
Y1 - 2017/10/
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Van Ness, K P
A1 - Kavanagh, T J
A1 - Kelly, E J
T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core.
Y1 - 2018/03/11-15
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Weber, E J
A1 - Freedman, B S
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Sourcing of renal tubular epithelial cells from human stem cell-derived kidney organoids.
Y1 - 2015/11/3-8
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Weber, E J
T1 - Ex vivo induction of polymyxin-induced nephrotoxicity in a 3D microphysiological model of a human kidney proximal tubule.
Y1 - 2015/09/17-18
N1 - R835738C002
ER -
TY - CONF
A1 - Weber, E J
A1 - Vaara, M
A1 - Vaara, T
A1 - Neumann, T
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Ex vivo induction of polymyxin-induced nephrotoxicity in a 3D microphysiological model of a human kidney proximal tubule.
Y1 - 2016/03/13-17
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Weber, E J
A1 - Vaara, M
A1 - Vaara, T
A1 - Neumann, T
A1 - Himmelfarb, J
A1 - Kelly, E J
T1 - Safety assessment of Polymyxin B structural variants using a 3D nephrotoxin-sensitive microphysiological system.
Y1 - 2016/09/29-30
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
A1 - Weber, E
A1 - Vaara, M
A1 - Vaara, T
A1 - Neumann, T
A1 - Himmelfarb, J
A1 - Kelly, E
T1 - Polycationic antibiotic exposure validates clinical findings using a 3D microphysiological kidney-on-a-chip.
Y1 - 2017/08/20-24
N1 - R835738C002
N1 - R835738
ER -
TY - CONF
T1 - “Pathophysiological Responses of Proximal Tubule Epithelial Cells to Human Serum” 2018 Kidney International.
N1 - R835738C002
ER -
TY - Symposium
T1 - .
N1 - R835738C005
N1 - R835738C002
N1 - R835738
N1 - R835738C001
ER -