TY  - JOUR
A1  - Blanchette, A D
A1  - Grimm, F A
A1  - Dalaijamts, C 
A1  - Hsieh, N H
A1  - Ferguson, K 
A1  - Luo
YS,  
A1  - Anson, B 
A1  - Rusyn, I 
A1  - Chiu, W A
T1  - Thorough QT/QTc in a dish: An in vitro human model that accurately
predicts clinical concentration-QTc relationships.
Y1  - 2019//
N1  - R835802
N1  - R835802C001
JF  - CLINICAL PHARMACOLOGY AND THERAPEUTICS
VL  - 105
SP  - 1175
EP  - 1186.
ER  - 


TY  - JOUR
A1  - Chiu, W A
A1  - Axelrad, D A
A1  - Dalaijamts, C 
A1  - Dockins, C 
A1  - Shao, K 
A1  - Shapiro, A J
A1  - Paoli, G 
T1  - Beyond the RfD: Broad application of a probabilistic approach to improve chemical dose-response assessments for noncancer effects.
Y1  - 2018/06/
N1  - R835802
N1  - R835802C001
VL  - 126
IS  - 6
SP  - 067009
ER  - 


TY  - JOUR
A1  - Cote, I 
A1  - Andersen, M E
A1  - Ankley, G T
A1  - Barone, S 
A1  - Birnbaum, L S
A1  - Boekelheide, K 
A1  - Bois, F Y
A1  - Burgoon, L D
A1  - Chiu, W A
A1  - Crawford-Brown, D 
A1  - Crofton, K M
A1  - DeVito, M 
A1  - Devlin, R B
A1  - Edwards, S W
A1  - Guyton, K Z
A1  - Hattis, D 
A1  - Judson, R S
A1  - Knight, D 
A1  - Krewski, D 
A1  - Lambert, J 
A1  - Maull, E A
A1  - Mendrick, D 
A1  - Paoli, G M
A1  - Patel, C J
A1  - Perkins, E J
A1  - Poje, G 
A1  - Portier, C J
A1  - Rusyn, I 
A1  - Schulte, P A
A1  - Simeonov, A 
A1  - Smith, M T
A1  - Thayer, K A
A1  - Thomas, R S
A1  - Thomas, R 
A1  - Tice, R R
A1  - Vandenberg, J J
A1  - Villeneuve, D L
A1  - Wesselkamper, S 
A1  - Whelan, M 
A1  - Whittaker, C 
A1  - White, R 
A1  - Xia, M 
A1  - Yauk, C 
A1  - Zeise, L 
A1  - Zhao, J 
A1  - DeWoskin, R S
T1  - The next generation of risk assessment multi-year study--highlights of findings, applications to risk assessment, and future directions.
Y1  - 2016/04/
N1  - R835802
N1  - R835802C001
N1  - R835166
VL  - 124
IS  - 11
SP  - 1671
EP  - 1682
ER  - 


TY  - JOUR
A1  - Fantke, P 
A1  - Aylward, L 
A1  - Bare, J 
A1  - Chiu, W A
A1  - Dodson, R 
A1  - Dwyer, R 
A1  - Ernstoff, A 
A1  - Howard, B 
A1  - Jantunen, M 
A1  - Jolliet, O 
A1  - Judson, R 
A1  - Kirchhübel, N 
A1  - Li, D 
A1  - Miller, A 
A1  - Paoli, G 
A1  - Price, P 
A1  - Rhomberg, L 
A1  - Shen, B 
A1  - Shin, H M
A1  - Teeguarden, J 
A1  - Vallero, D 
A1  - Wambaugh, J 
A1  - Wetmore, B A
A1  - Zaleski, R 
A1  - McKone, T E
T1  - Advancements in life cycle human exposure and toxicity characterization.
Y1  - 2018//
N1  - R835802
N1  - R835802C001
JF  - ENVIRONMETNAL HEALTH PERSPECTIVE
VL  - 126
SP  - 125001
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - Iwata, Y 
A1  - Sirenko, O 
A1  - Bittner, M 
A1  - Rusyn, I 
T1  - High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes.
Y1  - 2015/11/
N1  - R835802
N1  - R835802C001
VL  - 13
IS  - 9
SP  - 529
EP  - 546
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - Iwata, Y 
A1  - Sirenko, O 
A1  - Chappell, G A
A1  - Wright, F A
A1  - Reif, D M
A1  - Braisted, J 
A1  - Gerhold, D L
A1  - Yeakley, J M
A1  - Shepard, P 
A1  - Seligmann, B 
A1  - Roy, T 
A1  - Boogaard, P J
A1  - Ketelslegers, H B
A1  - Rohde, A M
A1  - Rusyn, I 
T1  - A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.
Y1  - 2016/08/21
N1  - R835802
N1  - R835802C001
N1  - R835166
JF  - GREEN CHEMISTRY
J1  - ACS SYM SER
J2  - GREEN CHEM
VL  - 18
IS  - 16
SP  - 4407
EP  - 4419
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - Blanchette, A 
A1  - House, J S
A1  - Ferguson, K 
A1  - Hsieh, N H
A1  - Dalaijamts
C,  
A1  - Wright, A A
A1  - Anson, B 
A1  - Wright, F A
A1  - Chiu, W A
A1  - Rusyn, I 
T1  - A human population-based organotypic in vitro model for cardiotoxicity screening.
Y1  - 2018/07/
N1  - R835802
N1  - R835802C003
N1  - R835802C001
VL  - 35
IS  - 4
SP  - 441
EP  - 452.
ER  - 


TY  - JOUR
A1  - Grimm, F A
A1  - House, J S
A1  - Wilson, M R
A1  - Sirenko, O 
A1  - Iwata, Y 
A1  - Wright, F A
A1  - Ball
N,  
A1  - Rusyn, I 
T1  - Multi-Dimensional in Vitro Bioactivity Profiling for Grouping of Glycol Ethers.
Y1  - 2019/02/
N1  - R835802
N1  - R835802C001
N1  - R835166
JF  - REGULATORY TOXICOLOGY AND PHARMACOLOGY
J1  - REGUL TOXICOL PHARM
J2  - Regulatory Toxicology and Pharmacology
VL  - 101
SP  - 91
EP  - 102
ER  - 


TY  - JOUR
A1  - Konganti, K 
A1  - Ehrlich, A 
A1  - Rusyn, I 
A1  - Threadgill, D W
T1  - gQTL: a web application for QTL analysis using the collaborative cross mouse genetic reference population.
Y1  - 2018/06/
N1  - R835802
N1  - R835802C001
N1  - R835802C002
VL  - 8
IS  - 8
SP  - 2559
EP  - 2562
ER  - 


TY  - JOUR
A1  - Marvel, S W
A1  - To, K 
A1  - Grimm, F A
A1  - Wright, F A
A1  - Rusyn,  
A1  - Reif, D M
T1  - ToxPi Graphical User Interface 2.0: dynamic exploration, visualization, and sharing of integrated data models.
Y1  - 2018/03/5
N1  - R835802
N1  - R835802C003
N1  - R835802C001
JF  - BMC BIOINFORMATICS
VL  - 19
IS  - 1
SP  - 80 (7 pp.)
ER  - 


TY  - JOUR
T1  - Applying a global sensitivity analysis workflow to improve the
computational efficiencies in physiologically-based pharmacokinetic modeling.
N1  - R835802
N1  - R835802C001
JF  - FRONTIERS IN
 PHARMACOLOGY
ER  - 


TY  - CONF
A1  - Chiu, W 
T1  - Accurate clinical concentration-response predictions for cardiac
arrhythmias using a population-based in vitro/in silico model.
Y1  - 2019//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
A1  - Grimm, F A
A1  - Iwata, Y 
A1  - Sirenko, O 
A1  - Russell, W K
A1  - Luo, Y 
A1  - Crittenden, C 
A1  - Wright, F A
A1  - Reif, D M
A1  - Yeakley, J 
A1  - Seligmann, B 
A1  - Shepard, P 
A1  - Roy, T 
A1  - Boogaard, P J
A1  - Ketelslegers, H 
A1  - Rohde, A M
A1  - Rusyn, I 
T1  - Categorization of UVCBs using chemical-biological read across.
Y1  - 2016/03/13-17
N1  - R835802
N1  - R835802C001
N1  - R835166
ER  - 


TY  - CONF
A1  - Grimm, F 
A1  - Iwata, Y 
A1  - Sirenko, O 
A1  - Bittner, M 
A1  - Rusyn, I 
T1  - High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes.
Y1  - 2015/09/15-17
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
A1  - Iwata, Y 
A1  - Grimm, F 
A1  - Wilson, M 
A1  - Bittner, M 
A1  - Sirenko, O 
A1  - Rowlands, J C
A1  - Ball, N 
A1  - Rusyn, I 
T1  - Toxicological categorization of P-and E-series glycol ethers using high-content screening of human induced pluripotent stem cell (iPSC)-derived cells.
Y1  - 2016/03/13-17
N1  - R835802
N1  - R835802C001
N1  - R835166
ER  - 


TY  - CONF
A1  - Rusyn, I 
T1  - Mouse vs.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
A1  - Wilson, M R
A1  - Rowlands, J C
A1  - Ball, N 
A1  - Wignall, J A
A1  - Fourches, D 
A1  - Rusyn, I 
T1  - Data integration and visualization for transparent communication of the category read across: glycol ethers case study.
Y1  - 2015/06/16-17
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - A multi-tissue organotypic human in
vitro model for rapid hazard identification of environmental chemicals
and mixtures.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - An in vitro
human population model for assessment of inter-individual variability in
cardiotoxicity.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Application of the
WHO-IPCS dose-response framework to the human toxicity component of life
cycle impact analysis.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Beyond the RfD: Broad application of a probabilistic approach
to improve chemical dose-response assessments for non-cancer effects.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Development and use of
quantitative adverse outcome pathways: lessons learned from
application to cardiotoxicity.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Thorough QT/QTC in a dish: An in vitro human
model that accurately predicts clinical concentration-QTC relationships.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Thorough QT/QTc in a dish: An in vitro human model that accurately
predicts clinical concentration-QTc relationships.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Using ToxCast data in support of the key characteristics of
carcinogens:opportunities and challenges.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - WHO/IPCS probabilistic approach to improve chemical
dose-response assessments.
Y1  - 018.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - A multi-tissue organotypic
human in vitro model for rapid hazard identification of environmental
chemicals and mixtures.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Accurate clinical concentration-response predictions for cardiac
arrhythmias using a population-based in vitro/in silico model.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Enabling
Assessment of Cardiotoxicity Hazard for Environmental Chemicals Using An
In Vitro Human Population Model.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - POPKAT:
A Framework for Bayesian Population PBPK Analysis.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Probabilistic Dose-Response Assessment Using the
WHO/IPCS Framework.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - The
Utility of Informative Prior in Benchmark Dose Modeling for Animal
Reduction.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Thorough QT/QTc in a dish:An in vitro
human model that accurately predicts clinical concentration-QTc
relationships.
Y1  - 019.//
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - Initial Characterization of Hepatocytes Derived from Collaborative Cross Recombinant Inbred Mouse Strain iPSCs.
Y1  - 2018//
N1  - R835738C003
N1  - R835802
N1  - R835802C001
ER  - 


TY  - CONF
T1  - , Chiu, W.
N1  - R835802C001
ER  - 


TY  - CONF
T1  - , Craft, E.
N1  - R835802C001
ER  - 


TY  - CONF
T1  - S.
N1  - R835802C001
ER  -