TY - Abstract A1 - Altemeier, W A A1 - Haick, A A1 - Mittelsteadt, K L A1 - Kavanagh, T J T1 - Primary mouse airway epithelial cells are resistant to silver nanoparticles. Y1 - 2016/03/ N1 - R835738 N1 - R835738C001 JF - THE TOXICOLGIST VL - 150 IS - S-1 SP - 10 ER - TY - Abstract A1 - Chang, S A1 - Voellinger, J L A1 - White, C A1 - Kelly, E J A1 - Eaton, D L T1 - A tissue-engineered rat/human liver microphysiological system for drug and chemical testing. Y1 - 2015/03/ N1 - R835738C003 N1 - R835738 JF - THE TOXICOLOGIST VL - 144 IS - S-1 SP - 151 ER - TY - Abstract A1 - Faustman, E M T1 - Testicular cells co-culture as an alternative model for male reproductive toxicity. Y1 - 2017/03/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 VL - 151 IS - 1 SP - 144 ER - TY - Abstract A1 - Shaffer, A1 - R, M A1 - Wilder, C S A1 - Ryu, S Y A1 - Park, J L A1 - Hong, S A1 - White, C C A1 - Workman, T A1 - Griffith, W C A1 - Faustman, E M T1 - Lifestage-specific modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2017/03/ N1 - R835738C004 N1 - R835738 VL - 151 IS - 1 SP - 420 ER - TY - CHAP A1 - Van, N A1 - Kelly, E T1 - Excretory processes in toxicology: drug transporters in drug development. Y1 - 2018// N1 - R835738C002 N1 - R835738 N1 - R835738C001 VL - 1 SP - 143 EP - 164 ER - TY - JOUR A1 - Cartwright, M M A1 - Schmuck, S C A1 - Corredor, C A1 - Wang, B A1 - Scoville, D K A1 - Chisholm, C R A1 - Wilkerson, H W A1 - Afsharinejad, Z A1 - Bammler, T K A1 - Posner, J D A1 - Shutthanandan, V A1 - Baer, D R A1 - Mitra, S A1 - Altemeier, W A A1 - Kavanagh, T J T1 - The pulmonary inflammatory response to multiwalled carbon nanotubes is influenced by gender and glutathione synthesis. Y1 - 2016/10/ N1 - R835738 N1 - R835738C001 JF - REDOX BIOLOGY VL - 9 SP - 264 EP - 275 ER - TY - JOUR A1 - Chang, S A1 - Weber, E J A1 - Van, N A1 - Eaton, D L A1 - Kelly, E J T1 - Liver and kidney on chips: micro-physiological models to understand transporter function. Y1 - 2016/11/ N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 JF - CLINICAL PHARMACOLOGY & THERAPEUTICS VL - 100 IS - 5 SP - 464 EP - 478 ER - TY - JOUR A1 - Chang, S A1 - Weber, E J A1 - Sidorenko, V S A1 - Chapron, A A1 - Yeung, C K A1 - Gao, C A1 - Mao, Q A1 - Shen, D A1 - Wang, J A1 - Rosenquist, T A A1 - Dickman, K G A1 - Neumann, T A1 - Grollman, A P A1 - Kelly, E J A1 - Himmelfarb, J A1 - Eaton, D L T1 - Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Y1 - 2017/11/16 N1 - R835738C002 N1 - R835738 VL - 2 IS - 22 SP - 95978 (15 pp.) ER - TY - JOUR A1 - Chang, S-Y A1 - Voellinger, J L A1 - Van Ness, K P A1 - Chapron, B A1 - Shaffer, R M A1 - Neumann, T A1 - White, C C A1 - Kavanagh, T J A1 - Kelly, E J A1 - Eaton, D L T1 - Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity. Y1 - 2017/04/ N1 - R835738C003 N1 - R835738C002 N1 - R835738 JF - TOXICOLOGY IN VITRO J1 - TOXICOL IN VITRO VL - 40 SP - 170 EP - 183 ER - TY - JOUR A1 - Harris, S A1 - Hermsen, S A A1 - Yu, X A1 - Hong, S W A1 - Faustman, E M T1 - Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo. Y1 - 2015/12/ N1 - R835738C004 N1 - R834514C003 N1 - R835738 N1 - R834514 JF - REPRODUCTIVE TOXICOLOGY J1 - ADV EXP MED BIOL J2 - REPROD TOXICOL J3 - Reproductive Toxicology VL - 58 SP - 149 EP - 159 ER - TY - JOUR A1 - Harris, S A1 - Wegner, S A1 - Hong, S W A1 - Faustman, E M T1 - Phthalate metabolism and kinetics in an in vitro model of testis development. Y1 - 2016/04/01 N1 - R835738C004 N1 - R834514C003 N1 - R835738 N1 - R834514 N1 - R833772 VL - 32 SP - 123 EP - 131 ER - TY - JOUR A1 - Harris, S A1 - Shubin, S P A1 - Wegner, S A1 - Van, N A1 - Green, F A1 - Hong, S W A1 - Faustman, E M T1 - The presence of macrophages and inflammatory responses in an in vitro testicular co-culture model of male reproductive development enhance relevance to in vivo conditions. Y1 - 2016/10/ N1 - R835738C004 N1 - R834514C003 N1 - R835738 N1 - R834514 VL - 36 SP - 210 EP - 215 ER - TY - JOUR A1 - Kim, Y H A1 - Jo, M S A1 - Kim, J K A1 - Shin, J H A1 - Baek, J E A1 - Park, H S A1 - An, H J A1 - Lee, J S A1 - Kim, B W A1 - KH, K A1 - Ahn, K H A1 - Jeon, K S A1 - Oh, S M A1 - Lee, J H A1 - Workman, T A1 - Faustman, E M A1 - Yu, I J T1 - Short-term inhalation study of graphene oxide nanoplates. Y1 - 2018/04/ N1 - R835738C004 N1 - R835738C005 N1 - R835738 N1 - R835738C001 VL - 12 IS - 3 SP - 224 EP - 238 ER - TY - JOUR A1 - Kimmel, D W A1 - Rogers, L M A1 - Aronoff, D M A1 - Cliffel, D E T1 - Prostaglandin E2 regulation of macrophage innate immunity. Y1 - 2016/01/19 N1 - R835736 N1 - R835738 JF - CHEMICAL RESEARCH IN TOXICOLOGY J1 - CHEM RES TOXICOL VL - 29 IS - 1 SP - 19 EP - 25 ER - TY - JOUR A1 - Knudsen, T B A1 - Keller, D A A1 - Sander, M A1 - Carney, E W A1 - Doerrer, N G A1 - Eaton, D L A1 - Fitzpatrick, S C A1 - Hastings, K L A1 - Mendrick, D L A1 - Tice, R R A1 - Watkins, P B A1 - Whelan, M T1 - FutureTox II: in vitro data and in silico models for predictive toxicology. Y1 - 2015/02/ N1 - R835738C005 N1 - R835738 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 143 IS - 2 SP - 256 EP - 267 ER - TY - JOUR A1 - Lee, J H A1 - Han, J H A1 - Kim, J H A1 - Kim, B A1 - Bello, D A1 - Kim, J K A1 - Lee, GH A1 - Sohn, E K A1 - Lee, K A1 - Ahn, K A1 - Faustman, E M A1 - Yu, I J T1 - Exposure monitoring of graphene nanoplatelets manufacturing workplaces. Y1 - 2016/04/ N1 - R835738 JF - INHALATION TOXICOLOGY J1 - INHAL TOXICOL J2 - Inhal.Toxicol. VL - 28 IS - 6 SP - 281 EP - 291 ER - TY - JOUR A1 - Lee, J H A1 - Sung, J H A1 - Ryu, H R A1 - Song, K S A1 - Song, N W A1 - Park, H M A1 - Shin, B S A1 - Ahn, K A1 - Gulumian, M A1 - Faustman, E M A1 - Yu, I J T1 - Tissue distribution of gold and silver after subacute intravenous injection of co-administered gold and silver nanoparticles of similar sizes. Y1 - 2018/04/ N1 - R835738C004 N1 - R835738 JF - ARCHIVES OF TOXICOLOGY J1 - ARCH TOXICOL VL - 92 IS - 4 SP - 1393 EP - 1405 ER - TY - JOUR A1 - Nicholas, T A1 - Haik, A A1 - Bammler, T A1 - Workman, T A1 - Kavanaugh, T A1 - Faustman, E A1 - Gharib, S A1 - Altemeier, W T1 - The Effects of Genotype x Phenotype Interactions on Transcriptional Response to Silver Nanoparticle Toxicity in Organotypic Cultures of Murine Tracheal Epithelial Cells Y1 - 2020//01 N1 - R835738 JF - TOXICOLOGICAL SCIENCES J1 - TOXICOL SCI J2 - Toxicol.Sci. J3 - Toxicological Sciences VL - 173 IS - 1 SP - 121 EP - 143 ER - TY - JOUR A1 - Nocholas, T A1 - Haick, A A1 - Workman, T A1 - Griffith, W A1 - Nolin, J A1 - Kanahagh, T A1 - Faustman, E A1 - ALtemeir, W T1 - The effects of genotype x phenotype interactions on silver nanoparticle toxicity in organotypic cultures of murine tracheal epithelial cells Y1 - 2020//01 N1 - R835738 JF - NANOTOXICOLOGY J1 - Nanotoxicology VL - 14 IS - 7 SP - 908 EP - 928 ER - TY - JOUR A1 - Nolin, J D A1 - Lai, Y A1 - Ogden, H L A1 - Manicone, A M A1 - Murphy, R C A1 - An, D A1 - Frevert, C W A1 - Ghomashchi, F A1 - Naika, G S A1 - Gelb, M H A1 - Gauvreau, G M A1 - Piliponsky, A M A1 - Altemeier, W A A1 - Hallstrand, T S T1 - Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen. Y1 - 2017/11/2 N1 - R835738C002 N1 - R835738 N1 - R835738C001 VL - 2 IS - 21 SP - e94929 (18 pp.) ER - TY - JOUR A1 - Park, J J A1 - Weldon, B A A1 - Hong, S A1 - Workman, T A1 - Griffith, W C A1 - Park, J H A1 - Faustman, E M T1 - Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing. Y1 - 2018/04/ N1 - R835738C004 N1 - R835738C005 N1 - R835738 N1 - R835738C001 VL - 48 SP - 33 EP - 44 ER - TY - JOUR A1 - Ramaiahgari, S C A1 - Waidyanatha, S A1 - Dixon, D A1 - DeVito, M J A1 - Paules, R S A1 - Ferguson, S S T1 - From the cover: three-dimensional (3D) hepaRG spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte functionality for liver toxicity screening. Y1 - 2017/09/1 N1 - R835738 VL - 159 IS - 1 SP - 124 EP - 136 ER - TY - JOUR A1 - Rountree, A A1 - Karkamkar, A A1 - Khalil, G A1 - Folch, A A1 - Cook, D L A1 - Sweet, I R T1 - BaroFuse, a novel pressure-driven, adjustable-throughput perfusion system for tissue maintenance and assessment. Y1 - 2016/12/9 N1 - R835738 VL - 2 IS - 12 SP - e00210 (18 pp.) ER - TY - JOUR A1 - Scoville, D K A1 - Botta, D A1 - Galdanes, K A1 - Schmuck, S C A1 - White, C C A1 - Stapleton, P L A1 - Bammler, T K A1 - MacDonald, J W A1 - Altemeier, W A A1 - Hernandez, M A1 - Kleeberger, S R A1 - Chen, L C A1 - Gordon, T A1 - Kavanagh, T J T1 - Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice. Y1 - 2017/10/ N1 - R835738C002 N1 - R835738 N1 - R835738C001 VL - 31 IS - 10 SP - 4600 EP - 4611 ER - TY - JOUR A1 - Shaffer, R A1 - Smith, M N A1 - Faustman, E M T1 - Developing the regulatory utility of the exposome: mapping exposures for risk assessment through lifestage exposome snapshots (LEnS). Y1 - 2017/08/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 JF - ENVIRONMENTAL HEALTH PERSPECTIVES J1 - ENVIRON HEALTH PERSP J2 - Environ.Health Perspect. J3 - Environ Health Perspect J4 - Environmental Health Perspectives VL - 123 IS - 8 SP - 085003 (8 pp.) ER - TY - JOUR A1 - Smith, M N A1 - Grice, J A1 - Cullen, A A1 - Faustman, E M T1 - A toxicological framework for the prioritization of Children’s Safe Product Act data. Y1 - 2016/04/19 N1 - R835738C005 N1 - R835738 N1 - R834514 JF - INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH VL - 13 IS - 4 SP - 431 (24 pp.) ER - TY - JOUR A1 - Smith, M A1 - Hubal, E A1 - Faustman, E T1 - A Case study on the utility of predictive toxicology tools in alternatives assessments for hazardous chemicals in children's consumer products Y1 - 2020//09 N1 - R835738 JF - JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY J1 - JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY J2 - JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY VL - 30 IS - 1 SP - 160 EP - 170 ER - TY - JOUR A1 - Van Ness, K P A1 - Chang, S-Y A1 - Weber, E J A1 - Zumpano, D A1 - Eaton, D L A1 - Kelly, E J T1 - Microphysiological systems to assess nonclinical toxicity. Y1 - 2017/08/ N1 - R835738C005 N1 - R835738C002 N1 - R835738C004 N1 - R835738 N1 - R835738C001 VL - 73 IS - 1 SP - 14.18.1 EP - 14.18.28 ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D L T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835736C004 N1 - R835738C002 N1 - R835738 VL - 7 SP - 42296 (14 pp.) ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Estes, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D L T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835738C003 N1 - R835736C004 N1 - R835736 N1 - R835738C005 N1 - R835738 N1 - R835736C005 JF - SCIENTIFIC REPORTS J1 - Scientific Reports VL - 7 SP - 42296 (15 pp.) ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D T1 - Corrigendum: Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/03/16 N1 - R835738C005 N1 - R835738C002 N1 - R835738 JF - SCIENTIFIC REPORTS J1 - Scientific Reports VL - 7 SP - 44517 ER - TY - JOUR A1 - Wallace, J C A1 - Port, J A A1 - Smith, M N A1 - Faustman, E M T1 - FARME DB: a functional antibiotic resistance element database. Y1 - 2017/01/10 N1 - R835738 JF - DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION VL - 2017 IS - 1 SP - 1 EP - 7 ER - TY - JOUR A1 - Weber, E J A1 - Chapron, A A1 - Chapron, B D A1 - Voellinger, J L A1 - Lidberg, K A A1 - Yeung, C K A1 - Wang, Z A1 - Yamaura, Y A1 - Hailey, D W A1 - Neumann, T A1 - Shen, D D A1 - Thummel, K E A1 - Muczynski, K A A1 - Himmelfarb, J A1 - Kelly, E J T1 - Development of a microphysiological model of human kidney proximal tubule function. Y1 - 2016/09/ N1 - R835738C002 N1 - R835738 JF - KIDNEY INTERNATIONAL J1 - KIDNEY INT VL - 90 IS - 3 SP - 627 EP - 637 ER - TY - JOUR A1 - Weber, E J A1 - Himmelfarb, J A1 - Kelly, E J T1 - Concise review: current and emerging biomarkers of nephrotoxicity. Y1 - 2017/06/ N1 - R835738C002 N1 - R835738 JF - CURRENT OPINION IN TOXICOLOGY VL - 4 SP - 16 EP - 21 ER - TY - JOUR A1 - Wegner, S H A1 - Yu, X A1 - Pacheco, S A1 - Griffith, W C A1 - Faustman, E M T1 - Stage-specific signaling pathways during murine testis development and spermatogenesis: a pathway-based analysis to quantify developmental dynamics. Y1 - 2015/01/ N1 - R835738C004 N1 - R834514C003 N1 - R835738 N1 - R834514 JF - REPRODUCTIVE TOXICOLOGY J1 - ADV EXP MED BIOL J2 - REPROD TOXICOL J3 - Reproductive Toxicology VL - 51 SP - 31 EP - 39 ER - TY - JOUR A1 - Wegner, S A1 - Park, J A1 - Workman, T A1 - Hermsan, S A1 - Wallace, J A1 - Stanaway, I A1 - Kim, H A1 - Griffith, W A1 - Hong, S A1 - Faustman, E T1 - Anchoring a dynamic in vitro model of human neuronal differentiation to key processes of early brain development in vivo Y1 - 2020//01 N1 - R835738 N1 - R834514 JF - REPRODUCTIVE TOXICOLOGY J1 - ADV EXP MED BIOL J2 - REPROD TOXICOL J3 - Reproductive Toxicology VL - 91 SP - 116 EP - 130 ER - TY - JOUR A1 - Wegner, S A1 - Workman, T A1 - Park, J A1 - Harris, S A1 - Wallace, J A1 - Stanaway, I A1 - Hong, S A1 - Hansen, B A1 - Griffith, W A1 - Faustman, E T1 - A dynamic in vitro developing testis model reflects structures and functions of testicular development in vivo Y1 - 2023/06/01 N1 - R835738 N1 - R834514 JF - REPRODUCTIVE TOXICOLOGY J1 - ADV EXP MED BIOL J2 - REPROD TOXICOL J3 - Reproductive Toxicology VL - 118 IS - 108362 ER - TY - JOUR A1 - Weldon, B A A1 - Faustman, E M A1 - Oberdorster, G A1 - Workman, T A1 - Griffith, W C A1 - Kneuer, C A1 - Yu, I J T1 - Occupational exposure limit for silver nanoparticles: considerations on the derivation of a general health-based value. Y1 - 2016/09/ N1 - R835738C005 N1 - R835738 JF - NANOTOXICOLOGY J1 - Nanotoxicology VL - 10 IS - 7 SP - 945 EP - 956 ER - TY - JOUR A1 - Weldon, B A A1 - Park, J J A1 - Hong, S A1 - Workman, T A1 - Dills, R A1 - Lee, J H A1 - Griffith, W C A1 - Kavanagh, T J A1 - Faustman, E M T1 - Using primary organotypic mouse midbrain cultures to examine developmental neurotoxicity of silver nanoparticles across two genetic strains. Y1 - 2018/04/17 N1 - R835738C005 N1 - R835738C004 N1 - R835738 VL - 354 SP - 215 EP - 224 ER - TY - JOUR A1 - ZImaoka, T A1 - Yang, J A1 - Wang, L A1 - McDonald, M A1 - Afsharinejad, Z A1 - Bammler, T A1 - Van, N A1 - Yeung, C A1 - Rettie, A A1 - Himmelfarb, J T1 - Microphysiological system modeling of ochratoxin A-associated nephrotoxicity Y1 - 2020//01 N1 - R835738 JF - TOXICOLOGY J1 - TOXICOLOGY VL - 444 ER - TY - JOUR T1 - In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. Y1 - 2018/07/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 N1 - R835738C001 VL - 10 IS - 4 SP - e1507 ER - TY - CONF A1 - Altemeier, W A A1 - Haick, A A1 - Mittelsteadt, K L A1 - Kavanagh, T J T1 - Primary mouse airway epithelial cells are resistant to silver nanoparticles. Y1 - 2016/03/13-17 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Altemeier, W A A1 - Nolin, J D A1 - Lai, Y A1 - Mulligan, M S A1 - Hallstrand, T S T1 - Development of human organotypic culture systems to model airway biology. Y1 - 2017/08/20-24 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Altemeier, W A T1 - Development of human organotypic culture systems to model airway biology. Y1 - 2017/08/21 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Botta, D A1 - Schaupp, C M A1 - White, C C A1 - Dempsey, J L A1 - Kavanagh, T J T1 - Development of an immortalized glutathione deficient mouse hepatocyte cell line with Nrf2 reporter activity. Y1 - 2017/03/12-16 N1 - R835738 ER - TY - CONF A1 - Botta, D A1 - White, C C A1 - Melnikov, F A1 - Schaupp, C M A1 - Gallagher, E G A1 - Brooks, B W A1 - Kostal, J A1 - Voutchkova-Kostal, A M A1 - Anastas, P T A1 - Kavanagh, T J T1 - Using immortalized hepatocytes from wild-type and Gclm knock out mice to investigate the relative toxicity and Nrf2 activation of SN2 reactive electrophiles. Y1 - 2018/03/11-15 N1 - R835738C003 N1 - R835738 ER - TY - CONF A1 - Chang, S Y A1 - Weber, E A1 - Kelly, E J A1 - Eaton, D L T1 - Microphysiological systems to identify organ-organ interactions in toxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. Y1 - 2015/09/17-18 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Chang, S Y A1 - Weber, E A1 - Neumann, T A1 - Kelly, E J A1 - Eaton, D L T1 - Microphysiological Systems (MPS) to identify organ-organ interactions in tToxicology: hepatic metabolism enhances nephrotoxicity of aristolochic acid. Y1 - 2016/03/13-17 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Eaton, D T1 - New frontiers for linked microphysiological systems: integrated liver-kidney systems on a chip. Y1 - 2017/08/20-24 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Testicular cells co-culture as an alternative model for male reproductive toxicity. Y1 - 017.// N1 - R835738C002 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M A1 - Smith, M N T1 - Neurodevelopmental disorders and disease & opportunities for new chemical testing data: understanding new tools from federal chemical testing programs. Y1 - 2015/08/14 N1 - R835738C005 N1 - R835738C004 N1 - R835738 N1 - R834514 ER - TY - CONF A1 - Faustman, E M A1 - Kavanagh, T J A1 - Altemeier, W A1 - Kelly, E A1 - Griffith, W C A1 - Gao, X A1 - Van Ness, K A1 - Eaton, D L T1 - Predictive Toxicology Center for Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials. Y1 - 2015/03/22-26 N1 - R835738C005 N1 - R835738C002 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M A1 - Kavanagh, T J T1 - University of Washington Predictive Toxicology Center update. Y1 - 2015/03/22-26 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M A1 - Kavanagh, T J A1 - Altemeier, W A1 - Kelly, E A1 - Griffith, W C A1 - Gao, X A1 - Van Ness, K A1 - Eaton, D L T1 - Organotypic Cultures and Assessment of AOPs for Engineered Nanomaterials: results from the University of Washington Predictive Toxicology Center (PTC). Y1 - 2015/11/19-20 N1 - R835738C005 N1 - R835738C002 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Integrating in vitro studies for risk assessment of quantum dots: applications of dosimetry and benchmark evaluation methods. Y1 - 2015/10/18-22 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - 3D testis culture: challenges and opportunities for informing AOP. Y1 - 2016/08/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Virtual tissue modeling. Y1 - 2016/08/ N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Faustman, E M A1 - Smith, M T1 - Prioritizing toxic chemicals in children’s consumer products. Y1 - 2016/12/14 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Virtual tissue modeling. Y1 - 2016/02/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Framing our birth defects questions with systems biology: learning from our mentors. Y1 - 2016/06/26 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Exposomes for children's studies: importance of life stage considerations. Y1 - 2016/05/11 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Children matter: using a lifecourse approach to understanding safety assessment needs for children. Y1 - 2016/05/20 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Virtual tissue modeling. Y1 - 2016/05/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Systems biology methods for translation of scientific findings across model platforms: identifying normal development versus chemical signals in complex systems. Y1 - 2017/08/20-24 N1 - R835738C005 N1 - R835738C004 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Faustman, E M T1 - Using systems biology for linking genes and environment for alcohol research. Y1 - 2017/06/ N1 - R835738C004 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Faustman, E M T1 - Integrating systems biology and public health to implement 3Rs–what have we learned and what do we need to do? Presented at the Institutional Animal Care and Use Committee (IACUC) Conference, New Orleans, LA, March 19-20, 2017 (keynote speaker). Y1 - 2017/03/19-20 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Faustman, E A1 - French, E A1 - Eaton, D A1 - Kelly, E A1 - Kavanagh, T T1 - Using systems based approaches for refinement, integration and translation. Y1 - 2017/08/ N1 - R835738C003 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Faustman, E A1 - Weber, E T1 - MPS-related research. Y1 - 2017// N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Fitzpatrick, S C T1 - Incorporating in vitro reproductive and developmental assays into regulatory risk assessment. Y1 - 2017/03/12-16 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Kavanagh, T J A1 - Schaupp, C M A1 - Botta, D A1 - Schmuck, S A1 - White, C C A1 - Chisholm, C T1 - Measuring chemically-induced oxidative stress in genetically modified cultured mammalian liver cells. Y1 - 2015/04/23-24 N1 - R835738C003 N1 - R835738 ER - TY - CONF A1 - Kavanagh, T T1 - Comparing engineered nanomaterial toxicity across species, partcles and cell types: the benefit of 3D over 2D in vitro systems, and the role of genetics in predicting ENM adverse outcome. Y1 - 2016/08/ N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Kavanagh, T T1 - Educational tools for designing safer chemicals and predicting toxicity. Y1 - 2017/08/20-24 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kavanagh, T T1 - Experiences with collaborative cross for assessing gene X environment interactions for engineered nanomaterials:can we capture human variability in vitro-lessons from the Predictive Toxicology Center. Y1 - 2017/08/20-24 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Kidney on a chip: from toxicology to therapeutics. Y1 - 2015/11/3-8 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Development of a 3D human kidney microphysiological system for drug safety testing. Y1 - 2015/11/9-11 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing. Y1 - 2015/10/18-22 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing. Y1 - 2015/10/27 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - 3D culture system for in vitro nephrotoxicity testing. Y1 - 2015// N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - The 3 R’s of toxicology and the role of microphysiological systems. Y1 - 2016/12/13 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Utility of predictive toxicity testing in a 3D microphysiological model of the human kidney proximal tubule. Y1 - 2016/12/2 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Predictive toxicity testing in a 3D microphysiological model of the human kidney proximal tubule. Y1 - 2016/10/31 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Organs on chips and reducing the need for animal studies. Y1 - 2016/09/29-30 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Human kidney microphysiological system for drug and xenobiotic toxicity testing. Y1 - 2016// N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Identification and discrimination of cellular responses to new molecular entities utilizing a 3D model of the human kidney proximal tubule. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Predictive toxicity testing in a microphysiological model of the human kidney proximal tubule. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Preclinical approaches for addressing complex human health issues:aristolochic acid nephropathy. Y1 - 2017/01/6 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Kelly, E J T1 - Emergent technologies for evaluating drug and xenobiotic disposition. Y1 - 2017/09/24-28 N1 - R835738C005 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Kelly, E T1 - Bioengineered ex vivo models of human organs for predictive toxicity testing. Y1 - 2017/12/6 N1 - R835738C003 N1 - R835738C005 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Klieforth, B A1 - Shaffer, R M A1 - mith, M A1 - Faustman, E M T1 - Microphysiological system models and the Lautenberg Chemical Safety for the 21st Century Act. Y1 - 2017/08/20-24 N1 - R835738C005 N1 - R835738C002 N1 - R835738C004 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Lee, J H A1 - Han, J H A1 - Kim, J H A1 - Kim, B W A1 - Bello, D A1 - Kim, J K A1 - Lee, GH A1 - Ahn, K A1 - Faustman, E M A1 - Park, J D A1 - Yu, I J T1 - Exposure monitoring of graphene manufactureing workplace. Y1 - 2016/03/13-17 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Lidberg, K A A1 - Iversen, P L A1 - Himmelfarb, J A1 - Kelly, E J T1 - Evaluation of antisense oligonucleotide nephrotoxicity using a 3D microphysiological system. Y1 - 2016/09/29-30 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Nicholas, T A1 - Haick, A A1 - Faustman, E A1 - Altemeier, W A T1 - Optimization of airway epithelium organotypic culture models as a platform for adverse outcome pathway assessment of engineered nanomaterials. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Nicholas, T A1 - Haick, A A1 - Kavanagh, T J A1 - Faustman, E A1 - Altemeier, W A T1 - Optimization of three-dimensional airway epithelium co-culture system as a platform for adverse outcome pathway assessment of engineered nanomaterials. Y1 - 2017/03/12-16 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Nicholas, T A1 - Haick, A A1 - Kavangh, T J A1 - Faustman, E A1 - Altemeier, W A T1 - Differentiation state of airway epithelium organotypic culture models is a potential mediator of silver nanoparticle-induced toxicity. Y1 - 2018/03/11-15 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Park, J J A1 - Kim, H Y A1 - Wegner, S H A1 - Van, N A1 - Pacheco, S E A1 - Workman, T A1 - Hong, S A1 - Griffith, W C A1 - Faustman, E T1 - Histon modifications in proliferating and differentiating human neuronal progenitor cells after acute chlorpyrifos and arsenic exposures. Y1 - 2016/06/25-29 N1 - R835738 ER - TY - CONF A1 - Park, J J A1 - Weldon, B A A1 - Park, J H A1 - Cruishank, W A1 - Workman, T A1 - Hong, S A1 - Ward, T A1 - Griffith, W A1 - Kavanagh, T A1 - Faustman, E M T1 - C57BL/6 fetal mouse midbrain micromass culture: a case study of silver nanoparticles. Y1 - 2016/03/13-17 N1 - R835738 ER - TY - CONF A1 - Park, J J A1 - Weldon, B A A1 - Hong, S A1 - Workman, T A1 - Dills, R A1 - Griffith, W C A1 - Kavanagh, T J A1 - Faustman, E M T1 - Silver nanoparticles dosimetry-response comparison in in vitro primary organotypic C57BL/6 and A/J mouse midbrain micromass cultures at various developmental stages. Y1 - 2017/08/20-24 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Park, S A1 - Lee, J H A1 - Wilder, C A1 - Wegner, S A1 - Harris, S A1 - Hong, S A1 - Faustman, E M T1 - Organotypic modeling platform for identifying adverse response in testicular development. Y1 - 2016/05/ N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Pekow, C A1 - Altemeier, W A T1 - Practical promotion of the 3Rs in animal models of lung disease. Y1 - 2017/08/20-24 N1 - R835738C005 N1 - R835738 N1 - R835738C001 ER - TY - CONF A1 - Shaffer, R M A1 - Welder, C S A1 - Ryu, C A1 - Yi, H S A1 - Park, S Y A1 - Hong, S A1 - White, C C A1 - Workman, T A1 - Griffith, W C A1 - Faustman, E M T1 - Lifestage-specific organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2017/08/20-24 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Shaffer, R A1 - Wilder, C S A1 - Ryu, C A1 - Yi, H S A1 - Park, S Y A1 - Hong, S A1 - White, C C A1 - Workman, T A1 - Griffith, W C A1 - Faustman, E M T1 - Lifestage-specific modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2016/09/29-30 N1 - R835738C005 N1 - R835738C002 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Smith, M N A1 - Faustman, E M A1 - Grice, J T1 - Developing a toxicological framework for the interpretation of the Children's Safe Product Act data. Y1 - 2015/04/17 N1 - R835738C004 N1 - R835738 N1 - R834514 ER - TY - CONF A1 - Smith, M N A1 - Faustman, E M A1 - Grice, J T1 - Developing a toxicological framework for the interpretation of the Children’s Safe Product Act data. Y1 - 2015/04/17 N1 - R835738C005 N1 - R835738 N1 - R834514 ER - TY - CONF A1 - Smith, M N A1 - Grice, J A1 - Faustman, E M T1 - Using a toxicological framework for chemical prioritization from the Children’s Safe Product Act Y1 - 2015/12/7 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Smith, M N T1 - Developing a toxicological framework for the prioritization of the Children’s Safe Product Act data. Y1 - 2016/05/18 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Smith, M N A1 - Shaffer, R M A1 - Cohen, H A1 - Faustman, E T1 - Using in vitro data to compare endocrine disruption potential in hazardous chemicals currently found in children’s products and their proposed alternatives. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Song, H A1 - Kim, K A1 - Park, J J A1 - Hong, S A1 - Faustman, E M T1 - Neuronal developmental differences between C57BL/6 and A/J mice in micromass culture of mouse embryonic midbrain cell. Y1 - 2016/05/20 N1 - R835738 ER - TY - CONF A1 - Van, N A1 - Weber, E J A1 - Neumann, T A1 - Kelly, E J T1 - Nephrotoxicity of engineered nanoparticles: exposure effects of silver nanoparticles in a kidney microphysiological system. Y1 - 2016/03/13-17 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Van Ness, K P A1 - Kavanagh, T J A1 - Kelly, E J T1 - Microphysiological system assessment of nephrotoxicity of quantum dot with a cadmium/selenium core. Y1 - 2016/09/29-30 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Van Ness, K P A1 - Kavanagh, T J A1 - Kelly, E J T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Van Ness, K P A1 - Kavanagh, T J A1 - Kelly, E J T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core. Y1 - 2017/03/12-16 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Van Ness, K P A1 - Kavanagh, T J A1 - Kelly, E J T1 - Microphysiological system assessment of nephrotoxicity of quantum dot with a cadmium/selenium core. Y1 - 2017/10/ N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Van Ness, K P A1 - Kavanagh, T J A1 - Kelly, E J T1 - Microphysiological system assessment of nephrotoxicity of CdCl2 and quantum dots with a cadmium/selenium core. Y1 - 2018/03/11-15 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Weber, E J A1 - Freedman, B S A1 - Himmelfarb, J A1 - Kelly, E J T1 - Sourcing of renal tubular epithelial cells from human stem cell-derived kidney organoids. Y1 - 2015/11/3-8 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Weber, E J A1 - Vaara, M A1 - Vaara, T A1 - Neumann, T A1 - Himmelfarb, J A1 - Kelly, E J T1 - Ex vivo induction of polymyxin-induced nephrotoxicity in a 3D microphysiological model of a human kidney proximal tubule. Y1 - 2016/03/13-17 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Weber, E J A1 - Vaara, M A1 - Vaara, T A1 - Neumann, T A1 - Himmelfarb, J A1 - Kelly, E J T1 - Safety assessment of Polymyxin B structural variants using a 3D nephrotoxin-sensitive microphysiological system. Y1 - 2016/09/29-30 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Weber, E A1 - Vaara, M A1 - Vaara, T A1 - Neumann, T A1 - Himmelfarb, J A1 - Kelly, E T1 - Polycationic antibiotic exposure validates clinical findings using a 3D microphysiological kidney-on-a-chip. Y1 - 2017/08/20-24 N1 - R835738C002 N1 - R835738 ER - TY - CONF A1 - Weldon, B A A1 - Faustman, E M A1 - Oberdorster, G A1 - Workman, T A1 - Griffith, W C A1 - Kneuer, C A1 - Yu, I J T1 - A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. Y1 - 2015/09/17-18 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - Weldon, B A A1 - Faustman, E M A1 - Oberdorster, G A1 - Workman, T A1 - Griffith, W C A1 - Kneuer, C A1 - Yu, I J T1 - A framework for the derivation of a health-based occupation exposure limit for silver nanoparticles. Y1 - 2016/03/13-17 N1 - R835738C005 N1 - R835738 ER - TY - CONF A1 - White, C C A1 - Botta, D A1 - Schaupp, C M A1 - Kavanagh, T J T1 - Toxicological assessment of glutathione content, mitochondrial membrane potential and cardiolipin in an immortalized glutathione-deficient mouse hepatocyte cell line. Y1 - 2017/06/10-14 N1 - R835738C003 N1 - R835738 ER - TY - CONF A1 - Wilder, C S A1 - Wegner, S H A1 - Smith, M N A1 - Harris, S A1 - Hong, S W A1 - Griffith, W C A1 - Faustman, E M T1 - Organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2016/06/25-29 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Wilder, C S A1 - Wegner, S H T1 - Organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2016/05/ N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - CONF A1 - Wilder, C T1 - Organotypic modeling platform for adverse outcome pathways of male reproductive and developmental processes. Y1 - 2016/05/ N1 - R835738C004 N1 - R835738 ER - TY - CONF T1 - , Altemeier W, Kelly E, Griffith WC, Gao X, Van Ness K, Eaton DL. Y1 - 2015/11/19-20 N1 - R835738C005 N1 - R835738C004 N1 - R835738 ER - TY - Symposium T1 - . N1 - R835738C005 N1 - R835738C002 N1 - R835738 N1 - R835738C001 ER -