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Grantee Research Project Results

Associated Project Details for Research Category: Computational Toxicology

EPD06042 Integration of Biological High-Throughput Data with a Metabolic Model of a Liver Cell SBIR March 1, 2006 through August 31, 2006
R831846 Chemical Induced Changes in Gene Expression Patterns Along the HPG-axis at Different Organizational Levels Using a Small Animal Model (Japanese medaka) Grant September 1, 2004 through August 31, 2007
R831847 Estrogen Elicited Gene Expression Network Elucidation in the Rat Uterus Grant September 1, 2004 through August 31, 2007
R831848 Systems Biology Modeling of Fathead Minnow Response to Endocrine Disruptors Grant August 1, 2004 through July 31, 2007
R832720 Carolina Environmental Bioinformatics Center Centers October 1, 2005 through September 30, 2010
R832721 Environmental Bioinformatics and Computational Toxicology Center Centers October 1, 2005 through September 30, 2010
R832721C001 Development and Application of the DORIAN (Dose-Response Information Analysis) System Centers October 1, 2005 through September 30, 2010
R832721C002 Hepatocyte Metabolism Model for Xenobiotics Centers October 1, 2005 through September 30, 2010
R832721C003 Development of Computational Tools for Optimal Identification of Biological Networks Centers October 1, 2005 through September 30, 2010
R832721C004 Cheminformatics Tools for Toxicant Characterization Centers October 1, 2005 through September 30, 2010
R832721C005 Optimization Tools for In Silico Structural Proteomics Centers October 1, 2005 through September 30, 2010
R833825 Carolina Center for Computational Toxicology Centers April 1, 2008 through March 31, 2012
R834289 The Texas-Indiana Virtual STAR Center; Data-Generating in vitro and in silico Models of Developmental Toxicity in Embryonic Stem Cells and Zebrafish Centers November 1, 2009 through October 31, 2012
R840451 Assessment of neurotoxicity of mixtures of PFAS and other neuroactive organic pollutants through integrated in silico, in vitro cellular and in vivo models Grant October 1, 2022 through September 30, 2025
R840456 Protein Binding Affinity as the Driver for Studying PFAS Mixture Toxicity Grant September 1, 2022 through August 31, 2025
R840457 Oral toxicity assessment of PAH mixtures using an in vitro 3D cell culture bioreactor mimicking the in vivo intestinal tract environment Grant September 1, 2022 through May 1, 2025

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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