Grantee Research Project Results
Publications Details for Grant Number R834514C003
Molecular Mechanisms
RFA:
Children's Environmental Health and Disease Prevention Research Centers (with NIEHS) (2009)
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page with
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
Reference Type | Citation | Progress Report Year | Document Sources |
---|---|---|---|
Abstract | Faustman EM. 3-D in vitro models and systems biology: the phthalate syndrome as case example. Birth Defects Research Part A: Clinical and Molecular Teratology 2014;100(5):375. |
R834514C003 (2015) R834514C003 (Final) |
|
Abstract | Furlong CE, Li W-F, Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG. Effects of paraoxonase-1 (PON1) status on pre-and postnatal exposures to chlorpyrifos oxon and diazoxon. Neurotoxicology and Teratology 2014;43:85-86. |
R834514C003 (2015) |
|
Abstract | Pacheco SE, Wegner S, Green F, Harris S, Faustman EM. Presence of macrophases in an in vitro testicular coculture model of male reproductive development enhances relevance to in vivo conditions. Birth Defects Research Part A: Clinical and Molecular Teratology 2014;100(5):405. |
R834514C003 (2015) R834514C003 (Final) |
|
Abstract | Wegner S, Harris S, Stanaway I, Pacheco S, Park J, Hong S, Faustman EM. Pathway dynamics of an organotypic in vitro testicular model reflect developmental processes in vivo. Birth Defects Research Part A: Clinical and Molecular Teratology 2014;100(5):403. |
R834514C003 (2015) R834514C003 (Final) |
|
Book | Aschner M, Costa LG, eds. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. Waltham, MA: Elsevier, 2015, 436 pp. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book | Costa L, Aschner M, eds. Manganese in Health and Disease. Philadelphia, PA: Royal Society of Chemistry, 2014, 635 pp. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Avila DS, Costa LG, Aschner M. Manganese. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 995-997. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Caito S, Costa LG, Rongzhu L, Aschner M. Acrylonitrile. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 33-35. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Aschner M. Chickpea intoxication. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Volume 1, Second Edition. Waltham, MA: Elsevier, 2014, p. 773. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Giordano G, Aschner M. Domoic acid. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Volume 1, Second Edition. Waltham, MA: Elsevier, 2014, pp. 1016-1017. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Giordano G, Aschner M. Ethanol. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Volume 2, Second Edition. Waltham, MA: Elsevier, 2014, pp. 216-218. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Aschner M. Methanol. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Volume 2, Second Edition. Waltham, MA: Elsevier, 2014, p. 1116. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Aschner M. Organic solvents. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 694-695. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Giordano G, Aschner M. Polybrominated diphenyl ethers (PBDEs). In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. New York, NY: Elsevier, 2014, pp. 915-916. |
R834514 (2013) R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Giordano G. Polybrominated diphenyl ethers. In: Wexler P, ed. Encyclopedia of Toxicology, 3rd Edition. New York, NY: Elsevier, 2014, pp. 1032-1034. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG. Propoxur. In: Wexler P, ed. Encyclopedia of Toxicology, 3rd Edition. New York, NY: Elsevier, 2014, pp. 1111-1112. |
R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Aschner M. Smoking and nicotine. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, p. 226. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Giordano G, Aschner M. Snake venoms. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, p. 227. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Cole TB, Furlong CE. Paraoxonase (PON1) and detoxication of nerve agents. In: Gupta R, ed. Handbook of Toxicology of Chemical Warfare Agents, Second Edition. New York, NY: Elsevier, January 21, 2015, Chapter 73, pp. 1089-1098. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) R834514C004 (2015) |
|
Book Chapter | Costa LG. The neurotoxicity of organochlorine and pyrethroid pesticides. In: Lotti M, Bleeker M, eds. Handbook of Clinical Neurology, Occupational Neurology Volume 131, 3rd Series. New York, NY: Elsevier, 2015, Chapter 9, pp. 135-148. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Costa LG, Garrick J, Roque PJ, Pellacani C. Nutraceuticals in CNS diseases: potential mechanisms of neuroprotection. In: Gupta RC, ed. Nutraceuticals: Efficacy, Safety and Toxicity. New York, NY: Elsevier, 2016, Chapter 1, pp. 3-13. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Finkelstein Y, Martinez-Finley EJ, Costa LG, Aschner M. Lead. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 848-852. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Fretham SJB, Caito S, Martinez-Finley EJ, Giordano G, Costa LG, Aschner M. Neurotoxicology. In: Hayes AW, Kruger CL, eds. Hayes’ Principles and Methods of Toxicology, 6th Edition. Boca Raton, FL: CRC Press, October 2014, Chapter 33, pp. 1579-1600. |
R834514 (2013) R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Fretham SJB, Aschner M, Costa LG, Rocha JBT, Farina M. Mercury. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 1101-1103. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Book Chapter | Giordano G, Hong S, Faustman EM, Costa LG. Measurements of cell death in neuronal and glial cells. In: Costa LG, Giordano G, Guizzetti M, eds. In Vitro Neurotoxicology: Methods and Protocols, Methods in Molecular Biology Series Volume 758. New York: Humana Press, June 17, 2011, Chapter 11, pp. 171-178. |
R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Book Chapter | Martinez-Finley EJ, Costa LG, Finkelstein Y, Aschner M. Arsenic. In: Aminoff MJ, Daroff RB, eds. Encyclopedia of the Neurological Sciences, Second Edition. Waltham, MA: Elsevier, 2014, pp. 272-274. |
R834514 (2013) R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Journal Article | Costa LG, Pellacani C, Dao K, Kavanagh TJ, Roque PJ. The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. NeuroToxicology 2015;48:68-76. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Journal Article | Harris S, Hermsen SA, Yu X, Hong SW, Faustman EM. Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo. Reproductive Toxicology 2015;58:149-159. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) R835738 (2016) R835738 (2017) R835738C004 (2015) R835738C004 (2017) |
|
Journal Article | Harris S, Wegner S, Hong SW, Faustman EM. Phthalate metabolism and kinetics in an in vitro model of testis development. Toxicology in Vitro 2016;32:123-131. |
R833772 (2009) R834514 (Final) R834514C003 (Final) R835738 (2016) R835738 (2017) R835738C004 (2015) R835738C004 (2016) R835738C004 (2017) |
|
Journal Article | Harris S, Shubin SP, Wegner S, Van Ness K, Green F, Hong SW, Faustman EM. The presence of macrophages and inflammatory responses in an in vitro testicular co-culture model of male reproductive development enhance relevance to in vivo conditions. Toxicology In Vitro 2016;36:210-215. |
R834514 (Final) R834514C003 (Final) R835738 (2016) R835738 (2017) R835738C004 (2016) R835738C004 (2017) |
|
Journal Article | Kim HY, Wegner SH, Van Ness KP, Park JJ, Pacheco SE, Workman T, Hong S, Griffith W, Faustman EM. Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells. Reproductive Toxicology 2016;65:212-223. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Journal Article | Moreira EG, Yu X., Robinson JF, Griffith W, Hong SW, Beyer RP, Bammler TK, Faustman EM. Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos. Toxicology and Applied Pharmacology 2010;245(3):310-325. |
R831709 (2007) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Journal Article | Pizzurro DM, Dao K, Costa LG. Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione. Toxicology 2014;318:59-68. |
R834514C003 (Final) |
|
Journal Article | Pizzurro DM, Dao K, Costa LG. Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons. Toxicology and Applied Pharmacology 2014;274(3):372-382. |
R834514C003 (Final) |
|
Journal Article | Robinson JF, Guerrette Z, Yu X, Hong S, Faustman EM. A systems-based approach to investigate dose-and time-dependent methylmercury-induced gene expression response in C57BL/6 mouse embryos undergoing neurulation. Birth Defects Research. Part B: Developmental and Reproductive Toxicology 2010;89(3):188-200. |
R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Journal Article | Robinson JF, Griffith WC, Yu X, Hong S, Kim E, Faustman EM. Methylmercury induced toxicogenomic response in C57 and SWV mouse embryos undergoing neural tube closure. Reproductive Toxicology 2010;30(2):284-291. |
R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Journal Article | Robinson JF, Yu X, Moreira EG, Hong S, Faustman EM. Arsenic-and cadmium-induced toxicogenomic response in mouse embryos undergoing neurulation. Toxicology and Applied Pharmacology 2011;250(2):117-129. |
R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Journal Article | Robinson JF, Theunissen PT, van Dartel DA, Pennings JL, Faustman EM, Piersma AH. Comparison of MeHg-induced toxicogenomic responses across in vivo and in vitro models used in developmental toxicology. Reproductive Toxicology 2011;32(2):180-188. |
R834514 (Final) R834514C003 (Final) |
|
Journal Article | Wegner SH, Yu X, Pacheco Shubin S, Griffith WC, Faustman EM. Stage-specific signaling pathways during murine testis development and spermatogenesis: a pathway-based analysis to quantify developmental dynamics. Reproductive Toxicology 2015;51:31-39. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) R835738 (2016) R835738 (2017) R835738C004 (2015) R835738C004 (2017) |
|
Journal Article | Wegner S, Yu X, Kim HY, Harris S, Griffith WC, Hong S, Faustman EM. Effect of dipentyl phthalate in 3-dimensional in vitro testis co-culture is attenuated by cyclooxygenase-2 inhibition. Journal of Toxicology and Environmental Health Sciences 2014;6(8):161-169. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Journal Article | Yu X, Robinson JF, Sidhu JS, Hong S, Faustman EM. A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and ethylmercury in mouse embryonic fibroblast. Toxicological Sciences 2010;114(2):356-377. |
R831709 (2007) R834514 (2011) R834514 (2012) R834514 (2013) R834514 (Final) R834514C003 (Final) |
|
Journal Article | Zhou C, Chen J, Zhang X, Costa LG, Guizzetti M. Prenatal ethanol exposure up-regulates the cholesterol transporters ATP-binding cassette A1 and G1 and reduces cholesterol levels in the developing rat brain. Alcohol and Alcoholism 2014;49(6):626-634. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
|
Presentation | Faustman EM, Harris S, Park J, Hong S, Wegner S. An organotypic model of testes development: evaluation of diverse compounds and implications for high-content toxicity screening. Presented at the 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague, Czech Republic, August 24-28, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Faustman EM, Wegner S, Stanaway I, Park J, Pacheco S, Hong S. Defining normal developmental dynamics for human in vitro neuronal differentiation—applications for setting a baseline for adverse outcome assessments. Presented at the 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague, Czech Republic, August 24-28, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Faustman EM. Translating and integrating Tox 21 DNT for risk assessment: challenges and opportunities—where are we? Presented at the Children's Environmental Health Symposium, Sacramento, CA, February 2014. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Faustman EM. 3-D in vitro models and systems biology: the phthalate syndrome as a case example. Presented at the 54th Annual Meeting of the Teratology Society, Bellevue, WA, June 28-July 2, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Faustman EM, Costa LG. Molecular mechanisms of OP pesticides—role of astroglial cells and reactive oxygen species. Presented at the 2015 NIEHS/EPA Children's Environmental Health and Disease Prevention Research Centers Annual Meeting, October 29-30, 2015. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Furlong CE, Li W-F, Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG. Effects of paraoxonase-1 (PON1) status on pre-and postnatal exposures to chlorpyrifos oxon and diazoxon. Presented at the 38th Annual Meeting of the Neurobehavioral Teratology Society, Bellevue, WA, June 28-July 2, 2014 (invited). |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) R834514C004 (2015) R834514C004 (Final) |
not available |
Presentation | Harris S, Wegner S, Hong S, Faustman EM. Phthalate metabolism and kinetics in an in vitro model of testes development. Poster presented at the 53rd Society of Toxicology Annual Meeting & ToxExpo, Phoenix, AZ, March 23-27, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Harris S, Wegner S, Park J, Pacheco S, Hong S, Faustman EM. Investigating toxicity of diverse compounds in an organotypic model of testes development: impacts on cytotoxicity, cytokines, and testosterone production. Poster presented at the 54th Society of Toxicology Annual Meeting & ToxExpo, San Diego, CA, March 22-26, 2015. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Pacheco SE, Wegner S, Green F, Harris S, Faustman EM. Presence of macrophages in an in vitro testicular coculture model of male reproductive development enhances relevance to in vivo conditions. Presented at the 54th Annual Meeting of the Teratology Society, Seattle, WA, June 28-July 2, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Park JY, Lin YS, Phillips B, Vigoren EM, Thompson B, Faustman EM. Genetic polymorphisms and metabolic activities of CYP1A2, CYP2A6, XO, and NAT2 in agricultural communities in Eastern Washington. Poster presented at the 54th Society of Toxicology Annual Meeting & ToxExpo, San Diego, CA, March 22-26, 2015. |
R834514 (2015) R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Wegner S, Harris S, Stanaway I, Pacheco S, Park J, Hong S, Faustman EM. Pathway dynamics of an organotypic in vitro testicular model reflect developmental processes in vivo. Presented at the 54th Annual Meeting of the Teratology Society, Seattle, WA, June 28-July 2, 2014. |
R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Wegner S, Harris S, Pacheco S, Faustman EM. Dynamic expression of imprinted genes and epigenetic factors in an in vitro testicular coculture. Poster presented at the 53rd Society of Toxicology Annual Meeting & ToxExpo, Phoenix, AZ, March 23-27, 2014. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
Presentation | Wegner S, Stanaway I, Hermsen SAB, Kim H, Park J, Griffith WC, Hong S, Faustman EM. Anchoring a dynamic in vitro model of human neuronal differentiation to key processes of brain development in vivo. Poster presented at the 55th Annual Meeting of the Teratology Society, Montreal, Quebec, Canada, June 27-July 1, 2015. |
R834514 (Final) R834514C003 (2015) R834514C003 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.