Grantee Research Project Results
Publications Details for Grant Number R833452
Development of a PBPK Model for Interpreting Biomonitoring Data on Carbaryl and Other N-methyl-carbamates
RFA:
Interpretation of Biomarkers Using Physiologically Based Pharmacokinetic Modeling (2006)
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Abstract | Using in vitro pharmacokinetic and pharmacodynamic data to refine the pharmacokinetic model for carbaryl in the rat. | None | Yoon M, Kedderis GL, Tan Y-M, Clewell III HJ | Yoon M, Kedderis GL, Tan Y-M, Clewell III HJ. Using in vitro pharmacokinetic and pharmacodynamic data to refine the pharmacokinetic model for carbaryl in the rat. Poster Presented at the 49th Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 6–11, 2010 (Abstract #895). |
R833452 (Final) |
not available |
Journal Article | Use of in vitro data in developing a physiologically based pharmacokinetic model: Carbaryl as a case study. | TOXICOLOGY | Yoon M, Kedderis GL, Yan GZ, Clewell III HJ | Yoon M, Kedderis GL, Yan GZ, Clewell III HJ. Use of in vitro data in developing a physiologically based pharmacokinetic model: Carbaryl as a case study. Toxicology 2015;332:52-66. |
R833452 (Final) |
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Presentation | Kinetics of carbaryl biotransformation by freshly isolated Sprague-Dawley rat hepatocytes. | None | Kedderis GL, Yoon M, Tan Y-M, Clewell HJ | Kedderis GL, Yoon M, Tan Y-M, Clewell HJ. Kinetics of carbaryl biotransformation by freshly isolated Sprague-Dawley rat hepatocytes. Presented at the 48th Annual Meeting of the Society of Toxicology, Baltimore, MD, March 15–19, 2009 (abstract#1158). |
R833452 (2009) |
not available |
Presentation | Using in vitro pharmacokinetic and pharmacodynamic data to refine the pharmacokinetic model for carbaryl in the rat. | None | Yoon M, Kedderis GL, Tan Y-M, Clewell III | Yoon M, Kedderis GL, Tan Y-M, Clewell III. HJ. Using in vitro pharmacokinetic and pharmacodynamic data to refine the pharmacokinetic model for carbaryl in the rat. Poster presented at the 49th Annual Meeting of the Society of Toxicology, Salt Lake City, UT, March 6–11, 2010 (abstract submitted). |
R833452 (2009) R833452 (Final) |
not available |
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