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Grantee Research Project Results

Publications Details for Grant Number R832740

Integrated Microfluidic System for Bioluminescent Bioreporting, Separations, Vibrational Spectroscopy, and Microcantilever Transducer Evaluation of Endocrine Disrupting Chemicals

RFA: Exposure Measurement Tools for Endocrine Disrupting Chemicals in Mixtures (2005)

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Dissertation/Thesis (7)
Journal Article (32)
Presentation (15)
Proceedings (2)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Dissertation/Thesis Novel approaches to prepare and utilize surface-enhanced Raman spectroscopy (SERS) substrates: multiplex microfluidics and nanotransfer printing. None Abu-Hatab NA Abu-Hatab NA. Novel approaches to prepare and utilize SERS substrates: multiplex microfluidics and nanotransfer printing. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, May 2008. R832740 (2008)
R832740 (Final)
  • Full-text: University of Tennessee-Knoxville - PDF
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  • Abstract: University of Tennessee-Knoxville - Abstract
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Dissertation/Thesis Approaches to generating selectivity in microcantilever sensors. None Chapman PJ Chapman PJ. Approaches to generating selectivity in microcantilever sensors. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, May 2008. R832740 (2008)
R832740 (Final)
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Dissertation/Thesis Direct integration of surface enhanced Raman spectroscopy as a detection mode for microfluidic separations and fluid handling: μfluidic-SERS. None Connatser RM Connatser RM. Direct integration of surface enhanced Raman spectroscopy as a detection mode for microfluidic separations and fluid handling: μfluidic-SERS. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, December 2006. R832740 (Final)
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Dissertation/Thesis Development of nanomechanical sensors for environmental screening using protein functionalized microcantilevers. None Hill KL Hill KL. Development of nanomechanical sensors for environmental screening using protein functionalized microcantilevers. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, May 2010. R832740 (Final)
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Dissertation/Thesis The rational design and lithographic fabrication of surface enhanced Raman spectroscopy substrates. None Oran JM Oran JM. The rational design and lithographic fabrication of surface enhanced Raman spectroscopy substrates. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, August 2008. R832740 (2008)
R832740 (Final)
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Dissertation/Thesis Advances in biological separations. None Riddle L Riddle L. Advances in biological separations. Ph.D. Dissertation. Pfieffer College, Misenheimer, NC, 2006. R832740 (Final)
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Dissertation/Thesis Innovative methods of biomedical molecular analysis: capillary electrophoretic study of amyloid beta conformations and magnetically assisted transport evanescent field fluoro-assays. None Wellman AD Wellman AD. Innovative methods of biomedical molecular analysis: capillary electrophoretic study of amyloid beta conformations and magnetically assisted transport evanescent field fluoro-assays. Ph.D. Dissertation. Department of Chemistry, University of Tennessee-Knoxville, Knoxville, TN, May 2007. R832740 (Final)
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Journal Article Multiplexed microfluidic surface-enhanced Raman spectroscopy. None Abu-Hatab NA, John JF, Oran JM, Sepaniak MJ Abu-Hatab NA, John JF, Oran JM, Sepaniak MJ. Multiplexed microfluidic surface-enhanced Raman spectroscopy. Applied Spectroscopy 2007;61(10):1116-1122. R832740 (2007)
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Journal Article Surface-enhanced Raman spectroscopy substrates created via electron beam lithography and nanotransfer printing. None Abu-Hatab NA, Oran JM, Sepaniak MJ Abu-Hatab NA, Oran JM, Sepaniak MJ. Surface-enhanced Raman spectroscopy substrates created via electron beam lithography and nanotransfer printing. ACS Nano 2008;2(2):377-385. R832740 (2008)
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Journal Article Independent component analysis of nanomechanical responses of cantilever arrays. None Archibald R, Datskos P, Devault G, Lamberti V, Lavrik N, Noid D, Sepaniak M, Dutta P Archibald R, Datskos P, Devault G, Lamberti V, Lavrik N, Noid D, Sepaniak M, Dutta P. Independent component analysis of nanomechanical responses of cantilever arrays. Analytica Chimica Acta 2007;584(1):101-105. R832740 (2006)
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Journal Article Dual function surface-enhanced Raman active extractor for the detection of environmental contaminants. None Bhandari D, Walworth MJ, Sepaniak MJ Bhandari D, Walworth MJ, Sepaniak MJ. Dual function surface-enhanced Raman active extractor for the detection of environmental contaminants. Applied Spectroscopy 2009;63(5):571-578. R832740 (2008)
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Journal Article Characterization and detection of uranyl ion sorption on silver surfaces using surface enhanced Raman spectroscopy. ANALYTICAL CHEMISTRY Bhandari D, Wells SM, Retterer SD, Sepaniak MJ Bhandari D, Wells SM, Retterer SD, Sepaniak MJ. Characterization and detection of uranyl ion sorption on silver surfaces using surface enhanced Raman spectroscopy. Analytical Chemistry 2009;81(19):8061-8067. R832740 (Final)
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Journal Article Stamping plasmonic nanoarrays on SERS-supporting platforms. JOURNAL OF RAMAN SPECTROSCOPY Bhandari D, Wells SM, Polemi A, Kravchenko II, Shuford KL, Sepaniak MJ Bhandari D, Wells SM, Polemi A, Kravchenko II, Shuford KL, Sepaniak MJ. Stamping plasmonic nanoarrays on SERS-supporting platforms. Journal of Raman Spectroscopy 2011;42(11):1916-1924. R832740 (Final)
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Journal Article Facile hyphenation of gas chromatography and a microcantilever array sensor for enhanced selectivity. ANALYTICAL CHEMISTRY Chapman PJ, Vogt F, Dutta P, Datskos PG, Devault GL, Sepaniak MJ Chapman PJ, Vogt F, Dutta P, Datskos PG, Devault GL, Sepaniak MJ. Facile hyphenation of gas chromatography and a microcantilever array sensor for enhanced selectivity. Analytical Chemistry 2007;79(1):364-370. R832740 (2006)
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Journal Article Differentially ligand-functionalized microcantilever arrays for metal ion identification and sensing. None Chapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ Chapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ. Differentially ligand-functionalized microcantilever arrays for metal ion identification and sensing. Analytical Chemistry 2007;79(18):7062-7068. R832740 (2008)
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Journal Article Ligand-functionalized microcantilever arrays for metal ion sensing. None Chapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ Chapman PJ, Long Z, Datskos PG, Archibald R, Sepaniak MJ. Differentially ligand-functionalized microcantilever arrays for metal ion identification and sensing. Analytical Chemistry 2007;79(18):7062-7068. R832740 (2007)
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Journal Article Analytical optimization of nanocomposite surface-enhanced Raman spectroscopy/scattering detection in microfluidic separation devices. None Connatser RM, Cochran M, Harrison RJ, Sepaniak MJ Connatser RM, Cochran M, Harrison RJ, Sepaniak MJ. Analytical optimization of nanocomposite surface-enhanced Raman spectroscopy/scattering detection in microfluidic separation devices. Electrophoresis 2008;29(7):1441-1450. R832740 (2008)
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Journal Article Nanofabrication of densely packed metal-polymer arrays for surface-enhanced Raman spectrometry APPLIED SPECTROSCOPY De Jesus MA, Giesfeldt KS, Oran JM, Abu-Hatab NA, Lavrik NV, Sepaniak MJ De Jesus MA, Giesfeldt KS, Oran JM, Abu-Hatab NA, Lavrik NV, Sepaniak MJ. Nanofabrication of densely packed metal-polymer arrays for surface-enhanced Raman spectrometry. Applied Spectroscopy 2005;59(12):1501-1508. R832740 (2008)
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Journal Article Characterization of ligand-functionalized microcantilevers for metal ion sensing ANALYTICAL CHEMISTRY Dutta P, Chapman PJ, Datskos PG, Sepaniak MJ Dutta P, Chapman PJ, Datskos PG, Sepaniak MJ. Characterization of ligand-functionalized microcantilevers for metal ion sensing. Analytical Chemistry 2005;77(20):6601-6608. R832740 (2008)
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Journal Article Nanostructured cantilevers as nanomechanical immunosensors for cytokine detection. NANOBIOTECHNOLOGY Dutta P, Sanseverino J, Datskos PG, Sepaniak MJ Dutta P, Sanseverino J, Datskos PG, Sepaniak MJ. Nanostructured cantilevers as nanomechanical immunosensors for cytokine detection. NanoBiotechnology 2005;1(3):237-244. R832740 (2008)
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Journal Article Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. None Dutta P, Hill K, Datskos PG, Sepaniak MJ Dutta P, Hill K, Datskos PG, Sepaniak MJ. Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. Lab on a Chip 2007;7(9):1184-1191. R832740 (2007)
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Journal Article Microcantilever-based nanomechanical studies of the orphan nuclear receptor pregnane X receptor-ligand interactions. JOURNAL OF BIOMATERIALS AND NANOBIOTECHNOLOGY Hill KL, Dutta P, Long Z, Sepaniak MJ Hill KL, Dutta P, Long Z, Sepaniak MJ. Microcantilever-based nanomechanical studies of the orphan nuclear receptor pregnane X receptor-ligand interactions. Journal of Biomaterials and Nanobiotechnology 2011;2(2):133-142. R832740 (Final)
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Journal Article Morphological and chemical optimization of microcantilever surfaces for thyroid system biosensing and beyond. None Hill K, Dutta P, Zareba A, Eldridge ML, Sepaniak MJ Hill K, Dutta P, Zareba A, Eldridge ML, Sepaniak MJ. Morphological and chemical optimization of microcantilever surfaces for thyroid system biosensing and beyond. Analytica Chimica Acta 2008;625(1):55-62. R832740 (2007)
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Journal Article Enclosed pillar arrays integrated on a fluidic platform for on-chip separations and analysis. LAB ON A CHIP Lavrik NV, Taylor LC, Sepaniak MJ Lavrik NV, Taylor LC, Sepaniak MJ. Enclosed pillar arrays integrated on a fluidic platform for on-chip separations and analysis. Lab on a Chip 2010;10(8):1086-1094. R832740 (Final)
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Journal Article Nanotechnology and chip level systems for pressure driven liquid chromatography and emerging analytical separation techniques: a review. ANALYTICA CHIMICA ACTA Lavrik NV, Taylor LT, Sepaniak MJ Lavrik NV, Taylor LT, Sepaniak MJ. Nanotechnology and chip level systems for pressure driven liquid chromatography and emerging analytical separation techniques: a review. Analytica Chimica Acta 2011;694(1-2):6-20. R832740 (Final)
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Journal Article Landfill siloxane gas sensing using differentiating, responsive phase coated microcantilever arrays. ANALYTICAL CHEMISTRY Long Z, Storey J, Lewis S, Sepaniak MJ Long Z, Storey J, Lewis S, Sepaniak MJ. Landfill siloxane gas sensing using differentiating, responsive phase coated microcantilever arrays. Analytical Chemistry 2009;81(7):2575-2580. R832740 (Final)
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Journal Article Aluminium oxide nanostructured microcantilever arrays for nanomechanical-based sensing. ANALYTICAL CHEMISTRY Long Z, Hill K, Sepaniak MJ Long Z, Hill K, Sepaniak MJ. Aluminium oxide nanostructured microcantilever arrays for nanomechanical-based sensing. Analytical Chemistry 2010;82(10):4114-4121. R832740 (Final)
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Journal Article Aluminum Oxide Nanostructured Microcantilever Arrays for Nanomechanical-Based Sensing ANALYTICAL CHEMISTRY Long Z, Hill K, Sniak M Long Z, Hill K, Sniak M. Aluminum Oxide Nanostructured Microcantilever Arrays for Nanomechanical-Based Sensing. ANALYTICAL CHEMISTRY 2010;82(10):4114-4121. R832740 (Final)
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Journal Article Surface-Enhanced Raman Scattering (SERS) characterization of trace organoarsenic antimicrobials using silver/polydimethylsiloxane nanocomposites. APPLIED SPECTROSCOPY Olavarria-Fullerton J, Wells S, Ortiz-Rivera W, Sepaniak MJ, De Jesus MA Olavarria-Fullerton J, Wells S, Ortiz-Rivera W, Sepaniak MJ, De Jesus MA. Surface-Enhanced Raman Scattering (SERS) characterization of trace organoarsenic antimicrobials using silver/polydimethylsiloxane nanocomposites. Applied Spectroscopy 2011;65(4):423-428. R832740 (Final)
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Journal Article Design and characterization of hybrid morphology nanoarrays as plasmonic Raman probes for antimicrobial detection. APPLIED SPECTROSCOPY Olavarria-Fullerton J, Velez RA, Wells S, Sepaniak MJ, Hernandez-Rivera SP, De Jesus MA Olavarria-Fullerton J, Velez RA, Wells S, Sepaniak MJ, Hernandez-Rivera SP, De Jesus MA. Design and characterization of hybrid morphology nanoarrays as plasmonic Raman probes for antimicrobial detection. Applied Spectroscopy 2013;67(11):1315-1322. R832740 (Final)
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Journal Article Nanofabricated periodic arrays of silver elliptical discs as SERS substrates. None Oran JM, Hinde RJ, Abu-Hatab NA, Retterer ST, Sepaniak MJ Oran JM, Hinde RJ, Abu-Hatab NA, Retterer ST, Sepaniak MJ. Nanofabricated periodic arrays of silver elliptical discs as SERS substrates. Journal of Raman Spectroscopy 2008;39(12):1811-1820. R832740 (2007)
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Journal Article Screening of potentially hormonally active chemicals using bioluminescent yeast bioreporters. None Sanseverino J, Eldridge ML, Layton AC, Easter JP, Yarbrough J, Schultz TW, Sayler GS Sanseverino J, Eldridge ML, Layton AC, Easter JP, Yarbrough J, Schultz TW, Sayler GS. Screening of potentially hormonally active chemicals using bioluminescent yeast bioreporters. Toxicological Sciences 2009;107(1):122-134. R831302 (Final)
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Journal Article Analyte species and concentration identification using differentially functionalized microcantilever arrays and artificial neural networks. ANALYTICA CHIMICA ACTA Senesac LR, Dutta P, Datskos PG, Sepaniak MJ Senesac LR, Dutta P, Datskos PG, Sepaniak MJ. Analyte species and concentration identification using differentially functionalized microcantilever arrays and artificial neural networks. Analytica Chimica Acta 2006;558(1-2):94-101. R832740 (2008)
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Journal Article Factors associated with pesticide safety practices in farmworkers. None Strong LL, Thompson B, Koepsell TD, Meischke H Strong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81. R831709 (2005)
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R832740 (Final)
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Journal Article Extraction, separation, and fluorometric analysis of selected environmental contaminants. JOURNAL OF SEPARATION SCIENCE Walworth MJ, Connatser RM, Sepaniak MJ Walworth MJ, Connatser RM, Sepaniak MJ. Extraction, separation, and fluorometric analysis of selected environmental contaminants. Journal of Separation Science 2009;32(17):2985-2992. R832740 (Final)
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Journal Article Magnetically-assisted transport evanescent field fluoroimmunoassay. ANALYTICAL CHEMISTRY Wellman AD, Sepaniak MJ Wellman AD, Sepaniak MJ. Magnetically-assisted transport evanescent field fluoroimmunoassay. Analytical Chemistry 2006;78(13):4450-4456. R832740 (2006)
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Journal Article Multiplexed, waveguide approach to magnetically assisted transport evanescent field fluoroassays. None Wellman AD, Sepaniak MJ Wellman AD, Sepaniak MJ. Multiplexed, waveguide approach to magnetically assisted transport evanescent field fluoroassays. Analytical Chemistry 2007;79(17):6622-6628. R832740 (2007)
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Journal Article Controllable nanofabrication of aggregate-like nanoparticle substrates and evaluation for surface-enhanced Raman spectroscopy. ACS NANO Wells SM, Retterer SD, Oran JM, Sepaniak MJ Wells SM, Retterer SD, Oran JM, Sepaniak MJ. Controllable nanofabrication of aggregate-like nanoparticle substrates and evaluation for surface-enhanced Raman spectroscopy. ACS Nano 2009;3(12):3845-3853. R832740 (Final)
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Journal Article Controllable Nanotabrication of Aggregate-like Nanoparticle Substrates and Evaluation for Surface-Enhanced Raman Spectroscopy ACS NANO Wells S, Retterer S, Oran J, Sniak M Wells S, Retterer S, Oran J, Sniak M. Controllable Nanotabrication of Aggregate-like Nanoparticle Substrates and Evaluation for Surface-Enhanced Raman Spectroscopy. ACS NANO 2009;3(12):3845-3853. R832740 (Final)
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Presentation Differentially ligand-functionalized microcantilever arrays for metal Ion identification and sensing. None Devault G, Chapman P, Sepaniak MJ Devault G, Chapman P, Sepaniak MJ. Differentially ligand-functionalized microcantilever arrays for metal Ion identification and sensing. Presented at the Southeastern Regional Meeting of the American Chemical Society (SERMACS): Living and Working in a Material World, Nashville TN, November 12-15, 2008. R832740 (2008)
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Presentation Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. None Hill K, Dutta P, Sepaniak MJ Hill K, Dutta P, Sepaniak MJ. Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. Presented at the Federation of Analytical Chemists and Spectroscopy Societies Meeting, Memphis, TN, October 18, 2007. R832740 (2007)
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Presentation Control of SERS substrate morphology by electron beam lithography. None Oran JM, Hatab NA, Sepaniak MJ Oran JM, Hatab NA, Sepaniak MJ. Control of SERS substrate morphology by electron beam lithography. Presented at the Southeastern Regional Meeting of the American Chemical Society, Memphis, TN, November 2006. R832740 (2006)
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Presentation Toward integrated microfluidic system for bioluminescent bioreporting, separations, vibrational spectroscopy, and microcantilever transducer evaluation of EDCs. None Sepaniak MJ, Sayler GS, Connatser RM, Dutta PD Sepaniak MJ, Sayler GS, Connatser RM, Dutta PD, et al. Toward integrated microfluidic system for bioluminescent bioreporting, separations, vibrational spectroscopy, and microcantilever transducer evaluation of EDCs. Presented at the EPA STAR Progress Review Meeting, RTP, NC, July 2006. R832740 (2006)
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Presentation Nanomechanical approaches to achieving selectivity in biosensing using surface modified microcantilevers. None Sepaniak MJ, Datskos PG Sepaniak MJ, Datskos PG. Nanomechanical approaches to achieving selectivity in biosensing using surface modified microcantilevers. Presented at the Gordon Conference on BIO-MEMS, New London, CT, June 2006. R832740 (2006)
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Presentation Fluidic devices integrated with uniquely fabricated nanocomposite SERS features. None Sepaniak MJ, Connatser RM Sepaniak MJ, Connatser RM. Fluidic devices integrated with uniquely fabricated nanocomposite SERS features. Presented at the Federation of Analytical Chemists and Spectroscopy Societies Meeting, Orlando, FL, October 2006. R832740 (2007)
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Presentation Fluidic devices integrated with uniquely fabricated nanocomposite SERS features. None Sepaniak MJ, Connatser RM Sepaniak MJ, Connatser RM. Fluidic devices integrated with uniquely fabricated nanocomposite SERS features. Presented at the Federation of Analytical Chemists and Spectroscopy Societies Meeting, Orlando FL, September 2006. R832740 (2006)
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Presentation BioMEMS nanomechanical sensors based on surface modified microcantilevers. None Sepaniak MJ, Dutta P Sepaniak MJ, Dutta P. BioMEMS nanomechanical sensors based on surface modified microcantilevers. Presented at the Pittsburgh Conference, Chicago, IL, February 2007. R832740 (2007)
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Presentation Chemical and biochemical analysis using microfluidic platforms with optical detection in highly localized fields. None Sepaniak MJ, Abu-Hatab N, Wellman AD, John J, Connatser RM Sepaniak MJ, Abu-Hatab N, Wellman AD, John J, Connatser RM. Chemical and biochemical analysis using microfluidic platforms with optical detection in highly localized fields. Presented at the Federation of Analytical Chemists and Spectroscopy Societies Meeting, Memphis TN, October 18, 2007. R832740 (2007)
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Presentation Chemical and biochemical analysis using microfluidic platforms with optical detection in highly localized fields. None Sepaniak MJ, Abu-Hatab N, Wellman AD, John J, Connatser RM Sepaniak MJ, Abu-Hatab N, Wellman AD, John J, Connatser RM. Chemical and biochemical analysis using microfluidic platforms with optical detection in highly localized fields. Presented at the SPIE Meeting, Smart Biomedical Sensing V, Boston, MA, September 2007. R832740 (2007)
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Presentation Studies of electron beam lithographically-prepared pillar-silver nano-discs as SERS substrates. None Sepaniak MJ Sepaniak MJ. Studies of electron beam lithographically-prepared pillar-silver nano-discs as SERS substrates. Presented at the PittCon Conference & Expo, New Orleans, LA, March 2, 2008. R832740 (2008)
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Presentation Toward integrated microfluidic system for bioluminescent bioreporting, separations, vibrational spectroscopy, and microcantilever transducer evaluation of EDCs. None Sepaniak MJ Sepaniak MJ.Toward integrated microfluidic system for bioluminescent bioreporting, separations, vibrational spectroscopy, and microcantilever transducer evaluation of EDCs. Presented at the U.S. EPA Meeting, Tampa, FL, November 2008. R832740 (2008)
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Presentation Submicron pillar-fluidic systems for high performance chemical analysis. None Taylor L, Sepaniak MJ Taylor L, Sepaniak MJ. Submicron pillar-fluidic systems for high performance chemical analysis. Presented at the Center for Nanoscale Material Science Users Meeting, Oak Ridge, TN, Fall 2008. R832740 (2008)
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Presentation Development of magnetically assisted transport evanescent field fluoroimmunoassays. None Wellman AD, Sepaniak MJ Wellman AD, Sepaniak MJ. Development of magnetically assisted transport evanescent field fluoroimmunoassays. Presented at the Pittsburgh Conference, Orlando FL, March 2006. R832740 (2006)
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Presentation Rational design and fabrication of noble metal nanostructures as substrates for SERS analysis. None Wells S, Sepaniak MJ Wells S, Sepaniak MJ. Rational design and fabrication of noble metal nanostructures as substrates for SERS analysis. Presented at the Center for Nanoscale Material Science Users Meeting, Oak Ridge, TN, Fall 2008. R832740 (2008)
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Proceedings Chemical and biochemical analysis using microfluidic-localized field platforms. None Sepaniak M, Abu-Hatab N, Wellman A, John J, Connatser M Sepaniak M, Abu-Hatab N, Wellman A, John J, Connatser M. Chemical and biochemical analysis using microfluidic-localized field platforms. In: Cullum BM, Porterfield DM, eds. Proceedings SPIE Volume 6759, Smart Biomedical and Physiological Sensor Technology V, Boston, MA, October 4, 2007, p. 675902. R832740 (2007)
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Proceedings Nanofabrication of Disc on Pillar Substrates for Surface Enhanced Raman Spectroscopy XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY Sniak M, Wells S, Bhandari D, Larvik N Sniak M, Wells S, Bhandari D, Larvik N. Nanofabrication of Disc on Pillar Substrates for Surface Enhanced Raman Spectroscopy. XXII INTERNATIONAL CONFERENCE ON RAMAN SPECTROSCOPY 2010;1267:273 R832740 (Final)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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