Grantee Research Project Results
Publications Details for Grant Number R831300
Mechanistic Approach to Screening Chemicals and Mixtures for Endocrine Activity Using an Invertebrate Model
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. | MOLECULAR AND CELLULAR ENDOCRINOLOGY | Gorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA | Gorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA. A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. Molecular and Cellular Endocrinology 2006;247(1-2):91-102. |
R829358 (Final) R831300 (2005) R831300 (2006) R831300 (Final) R832739 (2008) |
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Journal Article | Crustacean endocrine toxicology: a review. | ECOTOXICOLOGY | LeBlanc GA | LeBlanc GA. Crustacean endocrine toxicology: a review. Ecotoxicology 2007;16(1):61-81. |
R826129 (Final) R831300 (Final) R832739 (2007) R832739 (Final) |
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Journal Article | Cross communication between signaling pathways: juvenoid hormones modulate ecdysteroid activity in a crustacean. | JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-COMPERATIVE EXPERIMENTAL BIOLOGY | Mu XY, LeBlanc GA | Mu XY, LeBlanc GA. Cross communication between signaling pathways: juvenoid hormones modulate ecdysteroid activity in a crustacean. Journal of Experimental Zoology Part A–Comparative Experimental Biology 2004;301A(10):793-801. |
R826129 (Final) R829358 (2004) R829358 (Final) R831300 (2004) |
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Journal Article | Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. | ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY | Mu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. | Mu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. Environmental Toxicology and Chemistry 2005;24(1):146-152. |
R829358 (2004) R829358 (Final) R831300 (2004) R831300 (Final) R832739 (2008) |
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Journal Article | The environmental-endocrine basis of gynandromorphism (intersex) in a crustacean. | INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES | Olmstead AW, LeBlanc GA | Olmstead AW, LeBlanc GA. The environmental-endocrine basis of gynandromorphism (intersex) in a crustacean. International Journal of Biological Sciences 2006;3(2):77-84. |
R831300 (Final) R832739 (2006) R832739 (2007) R832739 (2008) R832739 (Final) |
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Journal Article | Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. | JOURNAL OF EXPERIMENTAL BIOLOGY | Rider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA | Rider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA. Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. Journal of Experimental Biology 2005;208(Pt 1):15-23. |
R829358 (Final) R831300 (2004) R831300 (2006) R831300 (Final) R832739 (2008) |
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Journal Article | Atrazine stimulates hemoglobin accumulation in Daphnia magna: is it hormonal or hypoxic? | TOXICOLOGICAL SCIENCES | Rider CV, LeBlanc GA | Rider CV, LeBlanc GA. Atrazine stimulates hemoglobin accumulation in Daphnia magna: is it hormonal or hypoxic? Toxicological Sciences 2006;93(2):443-449. |
R829358 (Final) R831300 (Final) |
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Journal Article | The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna. | AQUATIC TOXICOLOGY | Wang HY, Olmstead AW, Li H, LeBlanc GA | Wang HY, Olmstead AW, Li H, LeBlanc GA. The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna. Aquatic Toxicology 2005;74(3):193-204. |
R831300 (2005) R831300 (Final) R832739 (2008) |
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Journal Article | Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna. | GENERAL AND COMPARATIVE ENDOCRINOLOGY | Wang YH, Wang G, LeBlanc GA | Wang YH, Wang G, LeBlanc GA. Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna. General and Comparative Endocrinology 2007;150(2):309-318. |
R831300 (2006) R831300 (Final) R832739 (2006) R832739 (2007) R832739 (Final) |
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Presentation | Coordinate regulation of hemoglobin production and reproduction in a crustacean by the hormone methyl farnesoate and their dysregulation by insecticidal insect growth regulators. | None | LeBlanc GA, Olmstead AW, Rider CV, Hoy H, Wasilak B | LeBlanc GA, Olmstead AW, Rider CV, Hoy H, Wasilak B. Coordinate regulation of hemoglobin production and reproduction in a crustacean by the hormone methyl farnesoate and their dysregulation by insecticidal insect growth regulators. Presented at e.hormone 2003, New Orleans, LA, October 16-18, 2003. |
R831300 (2004) |
not available |
Presentation | Linking endocrinology to assay: Assessing endocrine-disrupting toxicity of chemicals to invertebrates | None | LeBlanc GA, Olmstead AW, Mu X, Rider CV | LeBlanc GA, Olmstead AW, Mu X, Rider CV, et al. Linking endocrinology to assay: Assessing endocrine-disrupting toxicity of chemicals to invertebrates. Presented at the U.S. Environmental Protection Agency Program Review Meeting, Research Triangle Park, NC, 2004. |
R831300 (2005) |
not available |
Presentation | Do EAT-based screening assays offer protection to invertebrates? | None | LeBlanc GA | LeBlanc GA. Do EAT-based screening assays offer protection to invertebrates? Presented at the 26th Annual Meeting of the Society for Environmental Toxicology and Chemistry, Baltimore, MD, November 13-17, 2005. |
R831300 (2006) R831300 (Final) |
not available |
Presentation | Environmental signaling: sex is not just in the genes | None | LeBlanc GA | LeBlanc GA. Environmental signaling: sex is not just in the genes. Presented at the Carolina Society of Environmental Toxicology and Chemistry Annual Meeting, Raleigh, NC, 2005. |
R831300 (2005) |
not available |
Presentation | Daphnids and gastropods as models to assess endocrine function and toxicant-mediated dysfunction in invertebrates. | None | LeBlanc GA, Gooding MP, Olmstead AW, Mu X, Rider CV, Wang HY, Bai R | LeBlanc GA, Gooding MP, Olmstead AW, Mu X, Rider CV, Wang HY, Bai R. Daphnids and gastropods as models to assess endocrine function and toxicant-mediated dysfunction in invertebrates. Presented at the Meeting of the Daphnia Genomics Consortium, Bloomington, IN, January 17-19, 2006. |
R831300 (2006) R831300 (Final) |
not available |
Presentation | Antiecdysteroidal activity of juvenoid hormones in a crustacean. | None | Mu X, Hoy H, LeBlanc GA | Mu X, Hoy H, LeBlanc GA. Antiecdysteroidal activity of juvenoid hormones in a crustacean. Presented at e.hormone 2003, New Orleans, LA, October 16-18, 2003. |
R831300 (2004) |
not available |
Presentation | Daphnia magna: a crustacean model for juvenoid endocrine disruption. | None | Olmstead AW | Olmstead AW. Daphnia magna: a crustacean model for juvenoid endocrine disruption. Presented at the 26th Annual Meeting of the Society for Environmental Toxicology and Chemistry, Baltimore, MD, November 13-17, 2005. |
R831300 (2006) R831300 (Final) |
not available |
Presentation | Developmental toxicity of nitrates: is there a mechanistic link to nitric oxide? | None | Reeves BS, Wang HY, LeBlanc GA | Reeves BS, Wang HY, LeBlanc GA. Developmental toxicity of nitrates: is there a mechanistic link to nitric oxide? Presented at the Society of Toxicology 2006 Conference, San Diego, CA, March 5-9, 2006. |
R831300 (2006) R831300 (Final) |
not available |
Presentation | Mechanistic evaluation of the developmental toxicity of nitrogen oxides. | None | Reeves BS, Wang YH, LeBlanc GA | Reeves BS, Wang YH, LeBlanc GA. Mechanistic evaluation of the developmental toxicity of nitrogen oxides. Presented at the 46th Annual Meeting of the Society of Toxicology and ToxExpo, Charlotte, NC, March 25-29, 2007. |
R831300 (Final) |
not available |
Presentation | Endocrine active insecticides stimulate a putative stress-signaling pathway in daphnids | None | Rider CV, Buslinger L, Olmstead AW, Wasilak BA | Rider CV, Buslinger L, Olmstead AW, Wasilak BA, et al. Endocrine active insecticides stimulate a putative stress-signaling pathway in daphnids. Presented at the Fourth Society of Environmental Toxicology and Chemistry World Congress, Portland, OR, 2004. |
R831300 (2005) |
not available |
Presentation | Nuclear receptor gene superfamily of Daphnia pulex. | None | Thomson S, Wang HY, Reeves BS, LeBlanc GA | Thomson S, Wang HY, Reeves BS, LeBlanc GA. Nuclear receptor gene superfamily of Daphnia pulex. Presented at the Meeting of the Daphnia Genomics Consortium, Bloomington, IN, July 7-9, 2007. |
R831300 (Final) |
not available |
Presentation | Interaction of retinoid X receptor with environmental chemicals. | None | Wang HY, Wang G, LeBlanc GA | Wang HY, Wang G, LeBlanc GA. Interaction of retinoid X receptor with environmental chemicals. Presented at the 46th Annual Meeting of the Society of Toxicology and ToxExpo, Charlotte, NC, March 25-29, 2007. |
R831300 (Final) |
not available |
Presentation | Rapid detection of (anti)ecdysteroid and (anti)juvenoid activities of chemicals | None | Wang H, Mu X, LeBlanc GA | Wang H, Mu X, LeBlanc GA. Rapid detection of (anti)ecdysteroid and (anti)juvenoid activities of chemicals. Presented at the Fourth Society of Environmental Toxicology and Chemistry World Congress, Portland, OR, 2004. |
R831300 (2005) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.