Grantee Research Project Results
Publications Details for Grant Number R830839
Coronary Effects of Combustion-Source Particulate Matter
RFA:
Airborne Particulate Matter Health Effects: Cardiovascular Mechanisms (2002)
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Abstract | Air pollution and atherosclerosis: impact on vascular oxidative stress, dyslipidemia, and remodeling. | None | Campen MJ, Chen LC | Campen MJ, Chen LC. Air pollution and atherosclerosis: impact on vascular oxidative stress, dyslipidemia, and remodeling. The Toxicologist 2007. |
R830839 (Final) |
not available |
| Abstract | Exposure to whole gasoline engine emissions results in alterations of molecular pathways involved in progression of atherosclerosis. | THE TOXICOLOGIST | Lund AK, Knuckles T, Seagrave JC, Akata CO, McDonald JD, Campen MJ | Lund AK, Knuckles T, Seagrave JC, Akata CO, McDonald JD, Campen MJ. Exposure to whole gasoline engine emissions results in alterations of molecular pathways involved in progression of atherosclerosis. The Toxicologist 2007;96(1):138. |
CR831455 (Final) R830839 (Final) |
not available |
| Abstract | In vivo endothelial response of Tie2-GFP/ApoE deficient mice to whole diesel exhaust. | None | Maresh JG, Campen MJ, Reed MD, Shohet RV | Maresh JG, Campen MJ, Reed MD, Shohet RV. In vivo endothelial response of Tie2-GFP/ApoE deficient mice to whole diesel exhaust. The Toxicologist 2007. |
R830839 (Final) |
not available |
| Abstract | Health effects of inhaled gasoline engine emissions. | None | McDonald JD, Reed MD, Campen MJ, Barrett EG, Seagrave J, Mauderly JL | McDonald JD, Reed MD, Campen MJ, Barrett EG, Seagrave J, Mauderly JL. Health effects of inhaled gasoline engine emissions. In: Proceedings of 10th International Inhalation Symposium, Hannover, Germany, 2006. |
R830839 (Final) |
not available |
| Journal Article | Nonparticulate components of diesel exhaust promote constriction in coronary arteries from ApoE-/- mice. | TOXICOLOGICAL SCIENCES | Campen MJ, Babu NS, Helms GA, Pett S, Wernly J, Mehran R, McDonald JD | Campen MJ, Babu NS, Helms GA, Pett S, Wernly J, Mehran R, McDonald JD. Nonparticulate components of diesel exhaust promote constriction in coronary arteries from ApoE-/-mice. Toxicological Sciences 2005;88(1):95-102. |
R830839 (2004) R830839 (2005) R830839 (Final) |
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| Journal Article | Fresh gasoline emissions, not paved road dust, trigger alterations in cardiac repolarization in ApoE-/- mice. | CARDIOVASCULAR TOXICOLOGY | Campen MJ, McDonald JD, Reed MD, Seagrave JC | Campen MJ, McDonald JD, Reed MD, Seagrave JC. Fresh gasoline emissions, not paved road dust, alter cardiac repolarization in ApoE-/- mice. Cardiovascular Toxicology 2006;6(3-4):199-209. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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| Journal Article | Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. | TOXICOLOGICAL SCIENCES | Lund AK, Knuckles TL, Akata CO, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen MJ | Lund AK, Knuckles TL, Akata CO, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen MJ. Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. Toxicological Sciences 2007;95(2):485-494. |
CR831455 (Final) R830839 (2005) R830839 (Final) R831860 (2007) R831860 (Final) |
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| Journal Article | Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. | ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY | Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, Seagrave J-C, Knuckles TL, Campen MJ | Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, Seagrave J-C, Knuckles TL, Campen MJ. Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1–mediated pathways. Arteriosclerosis, Thrombosis, and Vascular Biology 2009;29(4):511-517. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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| Journal Article | Health effects of inhaled gasoline engine emissions. | INHALATION TOXICOLOGY | McDonald JD, Reed MD, Campen MJ, Barrett EG, Seagrave JC, Mauderly JL | McDonald JD, Reed MD, Campen MJ, Barrett EG, Seagrave JC, Mauderly JL. Health effects of inhaled gasoline engine emissions. Inhalation Toxicology 2007;19(Suppl 1):107-116. |
R830839 (2005) |
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| Journal Article | Heart rate variability in rodents: uses and caveats in toxicological studies. | CARDIOVASCULAR TOXICOLOGY | Rowan WH, Campen MJ, Wichers LB, Watkinson WP | Rowan III WH, Campen MJ, Wichers LB, Watkinson WP. Heart rate variability in rodents: uses and caveats in toxicological studies. Cardiovascular Toxicology 2007;7(1):28-51. |
CR831455 (Final) R830839 (2005) R830839 (Final) |
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| Presentation | Coronary effects of diesel exhaust particulate matter: preliminary data. | None | Campen MJ | Campen MJ. Coronary effects of diesel exhaust particulate matter: preliminary data. Presented at the American Lung Association Meeting, Tempe, AZ, February 7, 2004. |
R830839 (2003) |
not available |
| Presentation | ApoE mouse model of atherosclerosis confers susceptibility to extrapulmonary effects of diesel exhaust. | None | Campen MJ, Seagrave J, Blair L, Lucas S | Campen MJ, Seagrave J, Blair L, Lucas S. ApoE mouse model of atherosclerosis confers susceptibility to extrapulmonary effects of diesel exhaust. Presented at the Society of Toxicology 44th Annual Meeting, New Orleans, LA, March 6-10, 2005. |
R830839 (2004) R830839 (2005) R830839 (Final) |
not available |
| Presentation | Acute alteration in aortic matrix metalloproteinases following exposure to gasoline exhaust emissions in ApoE-/- mice. | None | Campen MJ, Knuckles T, Lund AK | Campen MJ, Knuckles T, Lund AK. Acute alteration in aortic matrix metalloproteinases following exposure to gasoline exhaust emissions in ApoE-/-mice. Presented at the U.S. EPA/NHLBI/NIEHS Sponsored Meeting on the Role of Air Pollutants in Cardiovascular Disease, Research Triangle Park, NC, October 12, 2006. |
R830839 (2005) R830839 (Final) |
not available |
| Presentation | Cardiovascular health effects of air pollution | None | Campen MJ | Campen MJ. Cardiovascular health effects of air pollution. Presented at the School of Medicine, East Carolina University, July 2005. |
R830839 (Final) |
not available |
| Presentation | Differential effects of particulate and vapor phase constituents on cardiopulmonary endpoints in a mouse model of coronary artery disease. | None | Campen MJ, Babu NS, Helms, Seagrave J, McDonald JD | Campen MJ, Babu NS, Helms, Seagrave J, McDonald JD. Differential effects of particulate and vapor phase constituents on cardiopulmonary endpoints in a mouse model of coronary artery disease. Submitted to Nanoparticle conference, Durham, NC, October 2005. |
R830839 (2004) |
not available |
| Presentation | Volatile organic air toxics, not particulates, promote constrictive effects of diesel exhaust on murine coronary arteries. | None | Campen MJ, Babu NS, Helms GA, Blair L, Lucas S, McDonald JD | Campen MJ, Babu NS, Helms GA, Blair L, Lucas S, McDonald JD. Volatile organic air toxics, not particulates, promote constrictive effects of diesel exhaust on murine coronary arteries. Submitted to the American Heart Association Scientific Sessions, Dallas, TX, November 2005. |
R830839 (2004) |
not available |
| Presentation | Acute and chronic cardiovascular health effects of gasoline and diesel engine emissions. | None | Lund AK, Knuckles T, Campen MJ | Lund AK, Knuckles T, Campen MJ. Acute and chronic cardiovascular health effects of gasoline and diesel engine emissions. Presented too the Department of Cardiology, University of Louisville, February 2006. |
R830839 (Final) |
not available |
| Presentation | Subchronic exposure to whole gasoline engine emissions results in alterations of molecular pathways involved in progression of atherosclerosis. | None | Lund AK, Knuckles T, Campen M.J | Lund AK, Knuckles T, Campen MJ. Subchronic exposure to whole gasoline engine emissions results in alterations of molecular pathways involved in progression of atherosclerosis. Presented at the Seventh Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Denver, CO, April 27-29, 2006. |
R830839 (2005) R830839 (Final) |
not available |
| Presentation | Cardiovascular health effects of air pollution: more than just particles. | None | Lund AK, Knuckles T, Campen MJ | Lund AK, Knuckles T, Campen MJ. Cardiovascular health effects of air pollution: more than just particles. Presented to the Department of Pharmacology and Toxicology, Michigan State University, July 2005. |
R830839 (Final) |
not available |
| Presentation | Coronary impact of non-particulate air pollutants. | None | Lund AK, Knuckles T, Campen MJ | Lund AK, Knuckles T, Campen MJ. Coronary impact of non-particulate air pollutants. Presented at the Mountain West Society of Toxicology Meeting, Santa Fe, NM, September 15, 2005. |
R830839 (Final) |
not available |
| Presentation | Coronary impact of vapor phase constituents of diesel exhaust. | None | Lund AK, Knuckles T, Campen MJ | Lund AK, Knuckles T, Campen MJ. Coronary impact of vapor phase constituents of diesel exhaust. Presented to the National Environmental Respiratory Center External Scientific Advisory Committee, May 2005. |
R830839 (Final) |
not available |
| Presentation | Exposure to gasoline engine emissions increases vascular reactive oxygen species and activates molecular pathways involved in progression of atherosclerosis. | None | Lund AK, Knuckles TL, Lucero J, Seagrave J, McDonald JD, Campen MJ | Lund AK, Knuckles TL, Lucero J, Seagrave J, McDonald JD, Campen MJ. Exposure to gasoline engine emissions increases vascular reactive oxygen species and activates molecular pathways involved in progression of atherosclerosis. Presented at the Eighth Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, Chicago, IL, April 19-21, 2007. |
R830839 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.