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Book Chapter (4)
Journal Article (17)
Presentation (8)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Book Chapter Conjugation and elimination of toxicants. None LeBlanc GA, Dauterman WC LeBlanc GA, Dauterman WC. Conjugation and elimination of toxicants. In: Hodgson E, Smart RC, eds. Introduction to Biochemical Toxicology, 3rd Edition. New York, NY: John Wiley & Sons, Inc., 2001, Chapter 6, pp. 115-136. R826129 (2000)
R826129 (Final)
R829358 (Final)
Book Chapter Acute toxicity. None LeBlanc GA LeBlanc GA. Acute toxicity. In: Hodgson E, ed. A Modern Textbook of Toxicology, 3rd Edition. Stamford, CT: Appleton & Lange, 2004, Chapter 11, pp. 215-224. R829358 (Final)
Book Chapter Basics of environmental toxicology. None LeBlanc GA LeBlanc GA. Basics of environmental toxicology. In: Hodgson E, ed. A Textbook of Modern Toxicology, 3rd Edition. Stamford, CT: Appleton & Lange, 2004, Chapter 26, pp. 463-478. R829358 (Final)
Book Chapter Endocrine system. None LeBlanc GA LeBlanc GA. Endocrine system. In: Hodgson E, ed. A Textbook of Modern Toxicology, Third Edition. Stamford, CT: Appleton & Lange, 2004, Chapter 17, pp. 299-316. R829358 (Final)
Journal Article A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. MOLECULAR AND CELLULAR ENDOCRINOLOGY Gorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA Gorr TA, Rider CV, Wang HY, Olmstead AW, LeBlanc GA. A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter. Molecular and Cellular Endocrinology 2006;247(1-2):91-102. R829358 (Final)
R831300 (2005)
R831300 (2006)
R831300 (Final)
R832739 (2008)
Journal Article Evaluating the toxicity of chemical mixtures. ENVIRONMENTAL HEALTH PERSPECTIVES LeBlanc GA, Olmstead AW LeBlanc GA, Olmstead AW. Evaluating the toxicity of chemical mixtures. Environmental Health Perspectives 2004;112(13):A729-A730. R829358 (Final)
Journal Article Chemical mixtures: greater-than-additive effects? ENVIRONMENTAL HEALTH PERSPECTIVES LeBlanc GA, Wang G LeBlanc GA, Wang G. Chemical mixtures: greater-than-additive effects? Environmental Health Perspectives 2006;114(9):A517-A518. R829358 (Final)
Journal Article Environmental antiecdysteroids alter embryo development in the crustacean Daphnia magna. JOURNAL OF EXPERIMENTAL ZOOLOGY Mu XY, LeBlanc GA Mu XY, LeBlanc GA. Environmental antiecdysteroids alter embryo development in the crustacean Daphnia magna. ournal of Experimental Zoology 2002;292(3):287-292. R826120 (Final)
R826129 (2001)
R826129 (Final)
R829358 (2003)
 not available
Journal Article Synergistic interaction of endocrine-disrupting chemicals: model development using an ecdysone receptor antagonist and a hormone synthesis inhibitor. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY Mu XY, LeBlanc GA Mu XY, LeBlanc GA. Synergistic interaction of endocrine-disrupting chemicals: model development using an ecdysone receptor antagonist and a hormone synthesis inhibitor. Environmental Toxicology and Chemistry 2004;23(4):1085-1091. R826129 (Final)
R829358 (2003)
R829358 (2004)
R829358 (Final)
Journal Article Cross communication between signaling pathways: juvenoid hormones modulate ecdysteroid activity in a crustacean. JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-COMPERATIVE EXPERIMENTAL BIOLOGY Mu XY, LeBlanc GA Mu XY, LeBlanc GA. Cross communication between signaling pathways: juvenoid hormones modulate ecdysteroid activity in a crustacean. Journal of Experimental Zoology Part A–Comparative Experimental Biology 2004;301A(10):793-801. R826129 (Final)
R829358 (2004)
R829358 (Final)
R831300 (2004)
Journal Article Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity. GENERAL AND COMPARATIVE ENDOCRINOLOGY Mu XY, LeBlanc GA Mu XY, LeBlanc GA. Developmental toxicity of testosterone in the crustacean Daphnia magna involves anti-ecdysteroidal activity. General and Comparative Endocrinology 2002;129(2):127-133. R826129 (Final)
R829358 (2003)
 not available
Journal Article Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY Mu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. Mu XY, Rider CV, Hwang GS, Hoy H, LeBlanc GA. Covert signal disruption: anti-ecdysteroidal activity of bisphenol A involves cross talk between signaling pathways. Environmental Toxicology and Chemistry 2005;24(1):146-152. R829358 (2004)
R829358 (Final)
R831300 (2004)
R831300 (Final)
R832739 (2008)
Journal Article Toxicity assessment of environmentally relevant pollutant mixtures using a heuristic model. INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT Olmstead AW, LeBlanc GA Olmstead AW, LeBlanc GA. Toxicity assessment of environmentally relevant pollutant mixtures using a heuristic model. Integrated Environmental Assessment and Management 2005;1(2):114-122. R829358 (Final)
Journal Article Juvenoid hormone methyl farnesoate is a sex determinant in the crustacean Daphnia magna. JOURNAL OF EXPERIMENTAL ZOOLOGY Olmstead AW, LeBlanc GA

Olmstead AW, LeBlanc GA. Juvenoid hormone methyl farnesoate is a sex determinant in the crustacean Daphnia magna. Journal of Experimental Zoology 2002;293(7):736-739.

R826129 (Final)
R829358 (2003)
 not available
Journal Article Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. ENVIRONMENTAL HEALTH PERSPECTIVES Olmstead AW, LeBlanc G

Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environmental Health Perspectives 2003;111(7):919-924.

R826129 (Final)
R829358 (2003)
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Journal Article Joint action of polycyclic aromatic hydrocarbons: predictive modeling of sublethal toxicity. AQUATIC TOXICOLOGY Olmstead AW, LeBlanc GA Olmstead AW, LeBlanc GA. Joint action of polycyclic aromatic hydrocarbons: predictive modeling of sublethal toxicity. Aquatic Toxicology 2005;75(3):253-262. R829358 (Final)
Journal Article Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. JOURNAL OF EXPERIMENTAL BIOLOGY Rider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA Rider CV, Gorr TA, Olmstead AW, Wasilak BA, LeBlanc GA. Stress signaling: coregulation of hemoglobin and male sex determination through a terpenoid signaling pathway in a crustacean. Journal of Experimental Biology 2005;208(Pt 1):15-23. R829358 (Final)
R831300 (2004)
R831300 (2006)
R831300 (Final)
R832739 (2008)
Journal Article An integrated addition and interaction model for assessing toxicity of chemical mixtures. TOXICOLOGICAL SCIENCES Rider CV, LeBlanc GA Rider CV, LeBlanc GA. An integrated addition and interaction model for assessing toxicity of chemical mixtures. Toxicological Sciences 2005;87(2):520-528. R829358 (Final)
Journal Article Atrazine stimulates hemoglobin accumulation in Daphnia magna: is it hormonal or hypoxic? TOXICOLOGICAL SCIENCES Rider CV, LeBlanc GA Rider CV, LeBlanc GA. Atrazine stimulates hemoglobin accumulation in Daphnia magna: is it hormonal or hypoxic? Toxicological Sciences 2006;93(2):443-449. R829358 (Final)
R831300 (Final)
Journal Article Effects of prenatal testosterone propionate on the sexual development of male and female rats: A dose-response study. TOXICOLOGICAL SCIENCES Wolf CJ, Hotchkiss A, Ostby JS, LeBlanc GA, Gray LE. Wolf CJ, Hotchkiss A, Ostby JS, LeBlanc GA, Gray LE. Effects of prenatal testosterone propionate on the sexual development of male and female rats: A dose-response study. Toxicological Sciences 2002;65(1):71-86. R826129 (2001)
R826129 (Final)
R829358 (2003)
 not available
Journal Article Interactive effects of vinclozolin and testosterone propionate on pregnancy and sexual differentiation of the male and female SD rat. TOXICOLOGICAL SCIENCES Wolf CJ, LeBlanc GA, Gray Jr. LE Wolf CJ, LeBlanc GA, Gray Jr. LE. Interactive effects of vinclozolin and testosterone propionate on pregnancy and sexual differentiation of the male and female SD rat. Toxicological Science 2004;78(1):135-143. R829358 (2003)
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Presentation Mechanistic evaluation of the toxicity of chemical mixtures. None LeBlanc GA , Mu X, Rider CV

LeBlanc GA , Mu X, Rider CV. Mechanistic evaluation of the toxicity of chemical mixtures. Presented at the U.S. Environmental Protection Agency Human Health Symposium-A STAR Progress Review Workshop, Washington, DC, April 9-10, 2003.

R829358 (2003)
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Presentation A framework for predicting mixture toxicity in an environmental toxicology context. None Olmstead AW, Rider CV, LeBlanc GA Olmstead AW, Rider CV, LeBlanc GA. A framework for predicting mixture toxicity in an environmental toxicology context. Presented at the Society of Toxicology Mixtures Workshop, Atlanta, GA, February 16-17, 2005. R829358 (Final)
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Presentation The search for a simple approach to a complex problem: modeling mixtures toxicity. None Rider CV, LeBlanc GA Rider CV, LeBlanc GA. The search for a simple approach to a complex problem: modeling mixtures toxicity. Presented at the 24th Annual Meeting of Society of Environmental Toxicology and Chemistry, Austin, TX, November 8-13, 2003. R829358 (Final)
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Presentation Endocrine active insecticides stimulate a putative stress-signaling pathway in daphnids. None Rider CV, LeBlanc GA Rider CV, LeBlanc GA. Endocrine active insecticides stimulate a putative stress-signaling pathway in daphnids. Presented at the 25th Annual Meeting of Society of Environmental Toxicology and Chemistry, Portland, OR, November 14-18, 2004. R829358 (Final)
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Presentation A mechanistic approach to incorporating toxicokinetic and toxicodynamic interactions into a mixture toxicity model. None Rider CV, LeBlanc GA Rider CV, LeBlanc GA. A mechanistic approach to incorporating toxicokinetic and toxicodynamic interactions into a mixture toxicity model. Presented at the Carolinas Chapter of the Society of Environmental Toxicology and Chemistry, Raleigh, NC, March 31-April 2, 2005. R829358 (Final)
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Presentation Atrazine stimulates stress-responsive hemoglobin induction in Daphnia magna: is it hormonal or hypoxic? None Rider CV, LeBlanc GA Rider CV, LeBlanc GA. Atrazine stimulates stress-responsive hemoglobin induction in Daphnia magna: is it hormonal or hypoxic? Presented at the NCSU Graduate Student Research Symposium, Raleigh, NC, March 30, 2006. R829358 (Final)
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Presentation The search for a simple solution to a complex problem: modeling mixture toxicity. None Rider CV, LeBlanc GA

Rider CV, LeBlanc GA. The search for a simple solution to a complex problem: modeling mixture toxicity. Presented at the 24th Annual Meeting of the Society of Environmental Toxicology and Chemistry, Austin, TX, November 9-13, 2003.

R829358 (2004)
 not available
Presentation The search for a simple solution to a complex problem: modeling mixture toxicity. None Rider CV, LeBlanc GA

Rider CV, LeBlanc GA. The search for a simple solution to a complex problem: modeling mixture toxicity. Presented at the Advancing the Science of Entomology and Toxicology Symposium, Durham, NC, September 18-19, 2003.

R829358 (2003)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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