Grantee Research Project Results
Publications Details for Grant Number R829589
Analysis and Management of Fluxes in Bacillus Pathways for Pesticide and Protein Production
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | Closing the loop between feasible flux scenario identification for construct evaluation and resolution of realized fluxes via NMR. | COMPUTERS IN CHEMICAL ENGINEERING | Ghosh S, Zhu T, Grossmann IE, Ataai MM, Domach MM | Ghosh S, Zhu T, Grossmann IE, Ataai MM, Domach MM. Closing the loop between feasible flux scenario identification for construct evaluation and resolution of realized fluxes via NMR. Computers & Chemical Engineering 2005;29(3):459-466. |
R829589 (2003) R829589 (Final) |
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Journal Article | A three-level problem-centric strategy for selecting NMR precursor labeling and analytes. | None | Ghosh S, Zhu T, Grossman IE, Ataai MM, Domach MM | Ghosh S, Zhu T, Grossman IE, Ataai MM, Domach MM. A three-level problem-centric strategy for selecting NMR precursor labeling and analytes. Metabolic Engineering 2006;8(5):491-507. |
R829589 (Final) |
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Journal Article | Regulating expression of pyruvate kinase in Bacillus subtilis for control of growth rate and formation of acidic byproducts. | BIOTECHNOLOGY PROGRESS | Pan Z, Zhu T, Domagalski N, Khan S, Koepsel RR, Domach MM, Ataai MM | Pan Z, Zhu T, Domagalski N, Khan S, Koepsel RR, Domach MM, Ataai MM. Regulating expression of pyruvate kinase in Bacillus subtilis for control of growth rate and formation of acidic byproducts. Biotechnology Progress 2006;22(5):1451-1455. |
R829589 (Final) |
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Journal Article | A metabolic network analysis & NMR experiment design tool with user interface-driven model construction for depth-first search analysis. | MATABOLIC ENGINEERING | Zhu T, Phalakornkule C, Ghosh S, Grossmann IE, Koepsel RR, Ataai MM, Domach MM | Zhu T, Phalakornkule C, Ghosh S, Grossmann IE, Koepsel RR, Ataai MM, Domach MM. A metabolic network analysis & NMR experiment design tool with user interface-driven model construction for depth-first search analysis. Metabolic Engineering 2003;5(2):74-85. |
R829589 (2002) R829589 (2003) R829589 (Final) |
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Presentation | Flux enumeration via depth first search with MetaboLogica. | None | Grossman IE | Grossman IE. Flux enumeration via depth first search with MetaboLogica. Presented at the 225th American Chemical Society National Meeting, New Orleans, LA, March 23-27, 2003. |
R829589 (Final) |
not available |
Presentation | Integrated flux scenario identification and experimental design. | None | Grossman IE | Grossman IE. Integrated flux scenario identification and experimental design. Presented at the American Institute of Chemical Engineers 2003 Annual Meeting, San Francisco, CA, November 16-21, 2003. |
R829589 (Final) |
not available |
Presentation | Enhanced expression of green fluorescent protein in a PYK deficient E. coli mutant. | None | Grossman IE | Grossman IE. Enhanced expression of green fluorescent protein in a PYK deficient E. coli mutant. Presented at the 227th American Chemical Society National Meeting, Anaheim, CA, March 27-April 1, 2004. |
R829589 (Final) |
not available |
Presentation | Integrated pathway analysis and 13C NMR experimental design. | None | Grossman IE | Grossman IE. Integrated pathway analysis and 13C NMR experimental design. Presented at the 227th American Chemical Society National Meeting, Anaheim, CA, March 27-April 1, 2004. |
R829589 (Final) |
not available |
Presentation | Analyte selection for 13C NMR characterization of engineered cells. | None | Grossman IE | Grossman IE. Analyte selection for 13C NMR characterization of engineered cells. Presented at the American Institute of Chemical Engineers 2004 Annual Meeting, Austin, TX, November 7-12, 2004. |
R829589 (Final) |
not available |
Presentation | Effect of inducible PYK expression in B. subtilis. | None | Grossman IE | Grossman IE. Effect of inducible PYK expression in B. subtilis. Presented at the American Institute of Chemical Engineers 2004 Annual Meeting, Austin, TX, November 7-12, 2004. |
R829589 (Final) |
not available |
Presentation | Combining enhanced traits of E. coli into B. subtilis. | None | Grossman IE | Grossman IE. Combining enhanced traits of E. coli into B. subtilis. Presented at the 229th American Chemical Society National Meeting, San Diego, CA, March 13-17, 2005. |
R829589 (Final) |
not available |
Presentation | Design of NMR experiments for robust determination of metabolic fluxes. | None | Grossman IE | Grossman IE. Design of NMR experiments for robust determination of metabolic fluxes. Presented at the 229th American Chemical Society National Meeting, San Diego, CA, March 13-17, 2005. |
R829589 (Final) |
not available |
Presentation | Regulating expression of PYK in B. subtilis to reduce formation of acidic by-products and improve folic acid and recombinant protein production. | None | Grossman IE | Grossman IE. Regulating expression of PYK in B. subtilis to reduce formation of acidic by-products and improve folic acid and recombinant protein production. Presented at the 229th American Chemical Society National Meeting, San Diego, CA, March 13-17, 2005. |
R829589 (Final) |
not available |
Presentation | Acid reduction in Bacillus thuringiensis cultures. | None | Grossman IE | Grossman IE. Acid reduction in Bacillus thuringiensis cultures. To be presented at the American Institute of Chemical Engineers 2004 Annual Meeting, Austin, TX, November 7-12, 2004. |
R829589 (2003) |
not available |
Presentation | Optimally designing NMR experiments for metabolic flux determination. | None | Grossman IE | Grossman IE. Optimally designing NMR experiments for metabolic flux determination. To be presented at the American Institute of Chemical Engineers 2004 Annual Meeting, Austin, TX, November 7-12, 2004. |
R829589 (2003) |
not available |
Presentation | The updated software and use in another application. | None | Zhu T, Koepsel RR, Ataai MM, Grossmann IE, Domach MM | Zhu T, Koepsel RR, Ataai MM, Grossmann IE, Domach MM. The updated software and use in another application. Presented at the American Chemical Society Meeting, New Orleans, LA, April 2003. |
R829589 (2002) |
not available |
Presentation | Analysis and management of fluxes in Bacillus pathways for pesticide and protein production. | None | Zhu T, Koepsel RR, Ataai MM, Grossman IE, Domach MM | Zhu T, Koepsel RR, Ataai MM, Grossman IE, Domach MM. Analysis and management of fluxes in Bacillus pathways for pesticide and protein production. Presented at the 225th American Chemical Society National Meeting, New Orleans, LA, March 23-27, 2003. |
R829589 (2003) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.