Publications Details for:

In Vitro to In Vivo Screening of Thyroid Hormone Receptor Disrupting Chemicals
Grant Number R835164
RFA: Developing High-Throughput Assays for Predictive Modeling of Reproductive and Developmental Toxicity Modulated Through the Endocrine System or Pertinent Pathways in Humans and Species Relevant to Ecological Risk Assessment (2011)
Journal Article (5)
Presentation (5)
Reference Type Citation Progress Report Year Document Sources
Journal Article Freitas J, Miller N, Mengeling BJ, Xia M, Huang R, Houck K, Rietjens IM, Furlow JD, Murk AJ. Identification of thyroid hormone receptor active compounds using a quantitative high-throughput screening platform. Current Chemical Genomics and Translational Medicine 2014;8:36-46. R835164 (2012)
R835164 (Final)
Journal Article Mengeling BJ, Furlow JD. Pituitary specific retinoid-X receptor ligand interactions with thyroid hormone receptor signaling revealed by high throughput reporter and endogenous gene responses. Toxicology in Vitro 2015;29(7):1609-1618. R835164 (2012)
R835164 (Final)
Journal Article Mengeling BJ, Murk AJ, Furlow JD. Trialkyltin rexinoid-X receptor agonists selectively potentiate thyroid hormone induced programs of Xenopus laevis metamorphosis. Endocrinology 2016;157(7):2712-2723. R835164 (Final)
Journal Article Mengelinga BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. Aquatic Toxicology 2017;190:1-10. R835164 (Final)
R835550 (Final)
Journal Article Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V. Chasing the elusive benzofuran impurity of the THR antagonist NH-3: synthesis, isotope labeling, and biological activity. Journal of Organic Chemistry 2016;81(5):1870-1876. R835164 (Final)
R835550 (Final)
Presentation Furlow JD, Dobrawa LN, Wei Y, Streekstra M, Neff ES, Mengeling BJ, Murk AJ. In vitro to in vivo screening for thyroid hormone receptor active compounds. Poster presented at International Congress of Endocrinology (ICE)/ENDO 2014: the 96th Annual Endocrine Society Meeting and Expo, Chicago, IL, June 21-24, 2014. R835164 (Final)
not available
Presentation Furlow JD. In vitro and simplified in vivo assays for thyroid hormone disrupting chemicals: comparisons and perspectives for future testing paradigms. Presented at the 30th Workshop of the Scandinavian Society for Cell Toxicology, Järna, Sweden, October 13-15, 2015. R835164 (Final)
Presentation Furlow JD. Environmental disruption of thyroid hormone signaling: systems to cells back to (more) systems again. Presented at the Woods Hole Oceanographic Institute, Woods Hole, MA, 2015. R835164 (Final)
not available
Presentation Mengeling BJ, Furlow JD. RXR agonists potentiate and RXR antagonists block thyroid hormone-induced precocious metamorphosis in Xenopus tadpoles. Poster presented at ENDO 2015: the 97th Annual Endocrine Society Meeting & Expo, San Diego, CA, March 5-8, 2015. R835164 (Final)
Presentation Mengeling BJ, Furlow JD. RXR agonists potentiate and RXR antagonists block thyroid hormone induced precocious metamorphosis in Xenopus tadpoles. Presented at 25 Years of Endocrine Disruption Research: Past Lessons and Future Directions, Bethesda, MD, September 18-20, 2016. R835164 (Final)
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