Publications Details for:

A Multi-scale Dose-response Model of AHR Toxicity Pathway Activation in the Human Liver
Grant Number R835000
RFA: Computational Toxicology: Biologically-Based Multi-Scale Modeling (2010)
Book Chapter (1)
Journal Article (2)
Presentation (8)
Reference Type Citation Progress Report Year Document Sources
Book Chapter Bhattacharya S, Zhang Q, Roth RA, Andersen ME. The role of computational systems biology models in toxicity testing in the 21st century: an example with predictive multi-scale models of the liver. In: Wilson AGE, ed. New Horizons in Predictive Toxicology: Current Status and Application. Cambridge, UK: Royal Society of Chemistry, 2012, Chapter 24, pp. 614-691. R835000 (2012)
R835000 (Final)
Journal Article Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Frontiers in Physiology 2012;3:462. R835000 (2012)
R835000 (Final)
Journal Article McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. A map of the PPARα transcription regulatory network for primary human hepatocytes. Chemico-Biological Interactions 2014;209:14-24. R835000 (2013)
R835000 (Final)
Presentation Bhattacharya S, Woods CG, Yarborough KM, Efremenko A, Pluta L, Lu P, Dong J, Pi J, Andersen ME. A provisional regulatory network of PPARα-mediated transcription in primary human hepatocytes. Presented at the Wellcome Trust Functional Genomics and Systems Biology Conference, Hinxton, United Kingdom, November 29-December 1, 2011. R835000 (2011)
R835000 (Final)
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Presentation Bhattacharya S, McMullen P, Woods CG, Yarborough KM, Efremenko A, Pluta L, Lu P, Dong J, Pi J, Andersen ME. A provisional regulatory network of PPARα-mediated toxicity pathways in primary human hepatocytes. Presented at the North Carolina Society of Toxicology Spring Meeting, Research Triangle Park, NC, February 23, 2012. R835000 (2012)
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Presentation Bhattacharya S, McMullen P, Woods CG, Yarborough KM, Efremenko A, Pluta L, Lu P, Dong J, Pi J, Thomas RS, Andersen ME. A provisional regulatory network of PPAR-mediated transcription in primary human hepatocytes. Poster presented at Xenobiotic Receptors: 31st Summer Symposium in Molecular Biology, Penn State University, State College, PA, July 22-24, 2012. R835000 (2012)
R835000 (Final)
not available
Presentation Bhattacharya S, Woods CG, Yarborough KM, Efremenko A, Pluta L, Lu P, Dong J, Pi J, Andersen ME. A provisional regulatory network of PPARα-mediated transcription in primary human hepatocytes. Poster presented at the Society of Toxicology Annual Meeting, San Franscisco, CA, March 11-15, 2012. R835000 (2012)
not available
Presentation Bhattacharya S, McMullen PD, Pendse S, Andersen ME. A multiscale mechanistic model of TCDD-induced toxicity for assessing expected dose-responses for adverse outcome pathways in liver. Poster presented at the Society of Toxicology (SOT) Annual Meeting, Phoenix, AZ, March 24-27, 2014. R835000 (Final)
Presentation Bhattacharya S, McMullen PD, Pendse S, Andersen ME. A multiscale virtual tissue model of the liver lobule to assess zonal heterogeneity in AhR adverse outcome pathway-induced biological responses. Poster presented at the Society of Toxicology (SOT) Annual Meeting, San Diego, CA, March 22-26, 2015. R835000 (Final)
Presentation McMullen PD, Andersen ME, Bhattacharya S. A multiscale dose-response model of AhR toxicity pathway activation in the human liver. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 10-14, 2013. R835000 (2013)
R835000 (Final)
Presentation McMullen PD, Bhattacharya S, Woods CG, Sun B, Pendse S, LeCluyse EL, Clewell RA, Andersen ME. Species specificity of the peroxisome proliferator response in primary hepatocytes. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 10-14, 2013. R835000 (2013)
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