Publications for Center:

University of Washington Center for Child Environmental Health Risks Research

Grant Number R831709

Abstract (26)
Book (1)
Book Chapter (19)
Journal Article (107)
Presentation (20)
Proceedings (2)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Contribution of paraoxonase (PON1) levels and Q192R genotype to organophosphate detoxication: evidence from humans and "humanized" transgenic mice. TOXICOLOGICAL SCIENCES Cole TB, Walter BJ Cole, TB, Walter, BJ. Contribution of paraoxonase (PON1) levels and Q192R genotype to organophosphate detoxication:evidence from humans and "humanized" transgenic mice. The Toxicologist 2003;72(Suppl 1):100. R831709 (2005)
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Abstract Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. None Cole TB, Pettan-Brewer C, Forbes A, Proll A, Furlong J, Costa LG, Furlong CE Cole TB, Pettan-Brewer C, Forbes A, Proll A, Furlong J, Costa LG, Furlong CE. Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. The Toxicologist 2006;90:1446. R831709C002 (2007)
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Abstract Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. THE TOXICOLOGIST Faustman EM, Yu X, Sidhu J, Robinson J Faustman EM, Yu X, Sidhu J, Robinson J. Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. The Toxicologist 2005;84(S1):1655. R831709C001 (2005)
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Abstract Lessons learned from longitudinal studies to identify high exposure groups using OP pesticide urinary biomarkers. TOXICOLOGY LETTERS Faustman EM, Griffith WC, Vigoren E Faustman EM, Griffith WC, Vigoren E. Lessons learned from longitudinal studies to identify high exposure groups using OP pesticide urinary biomarkers. Toxicology Letters 2006;164(Suppl 1):S161. R831709 (2005)
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Abstract New polymorphisms in the human paraoxonase (PON1) gene. TOXICOLOGY SCIENCE Furlong CE, Rieder MJ, Carlson CS, Nickerson DA, Jampsa RL, Costa LG, Jarvik GP Furlong CE, Rieder MJ, Carlson CS, Nickerson DA, Jampsa RL, Costa LG, Jarvik GP. New polymorphisms in the human paraoxonase (PON1) gene. The Toxicologist 2003;72(Suppl 1):100. R831709 (2005)
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Abstract Differential modulation of stress and ubiquitination signaling pathways by Cadmium, H202, and serum withdrawal in cultrued mouse fibroblasts. TOXICOLOGIST Garry MR, Sidhu JS Garry MR, Sidhu JS. Differential modulation of stress and ubiquitination signaling pathways by Cadmium, H202, and serum withdrawal in cultrued mouse fibroblasts. The Toxicologist 2003;72:311. R831709 (2005)
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Abstract Reactive oxygen species mediate the neurotoxicity induced by organophosphorus insecticides in mouse cerebellar granule cells. TOXICOLOGIST Giordano G, Afsharinejad Z, Kavanagh T, Costa L Giordano G, Afsharinejad Z, Kavanagh T, Costa L. Reactive oxygen species mediate the neurotoxicity induced by organophosphorus insecticides in mouse cerebellar granule cells. The Toxicologist 2006;90(1):301. R831709 (2005)
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Abstract Reactive oxygen species mediate the neurotoxicity induced by organophosphorous insecticides in mouse cerebellar granule cells None Giordano G, Afsharinejad Z, Kavanagh T, Costa L Giordano G, Afsharinejad Z, Kavanagh T, Costa L. Reactive oxygen species mediate the neurotoxicity induced by organophosphorous insecticides in mouse cerebellar granule cells. The Toxicologist CD-An Official Journal of the Society of Toxicology 2006;90(S-1):1472a. R831709 (2007)
Abstract Computational models for the acquisition of neocortical neurons in the developing humans, monkey, and mouse: cross species comparison of toxicodynamics. THE TOXICOLOGIST Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational models for the acquisition of neocortical neurons in the developing humans, monkey, and mouse: cross species comparison of toxicodynamics. The Toxicologist 2005;84(S1):69. R831709C001 (2005)
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Abstract Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. TOXICOLOGIST Gohlke J, Griffith W, Faustman EM Gohlke J, Griffith W, Faustman EM. Evaluation of interspecies variability during neocortical neurogenesis using biologically based computational models. The Toxicologist 2003;72 (Suppl 1):179. R831709 (2005)
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Abstract Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts: Effects of methylmercury. TOXICOLOGIST Gribble E, Mendoza A Gribble E, Mendoza A. Evaluation of cell cycle kinetics in p53 mouse embryonal fibroblasts: effects of methylmercury. The Toxicologist 2003;72:322. R831709 (2005)
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Abstract Kinetic and dynamic characterization of a mouse embryonal mesencephalon neuronal precursor cell culture. BIRTH DEFECTS RESEARCH. PART A, CLINICAL MOLECULAR TERATOLOGY Gribble E, Hong S Gribble E, Hong S. Kinetic and dynamic characterization of a mouse embryonal mesencephalon neuronal precursor cell culture. Birth Defects Research Part A-Clinical Molecular Teratology 2005;73(5):301. R831709 (2005)
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Abstract A role for p53 in mouse midbrain neural precursor cell (NPC) cell cycle arrest and premature neuronal differentiation following methylmercury exposure. TOXICOLOGIST Gribble E, Yu X, Hong S, Faustman E Gribble EJ, Yu X, Hong S, Faustman EM. A role for p53 in mouse midbrain neural precursor cell (NPC) cell cycle arrest and premature neuronal differentiation following methylmercury exposure. The Toxicologist 2006;90:366. R831709 (2005)
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Abstract Building BBDR models for cell signaling pathways using transgenic animal models. TOXICOLOGIST Griffith W, Gohlke J Griffith W, Gohlke J. Building BBDR models for cell signaling pathways using transgenic animal models. The Toxicologist 2003;72:182. R831709 (2005)
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Abstract Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. TOXICOLOGIST Griffith W, DeFrank N Griffith W, DeFrank N. Systems biology models for integration of diverse studies of the developing neocortex after exposure to low dose radiation from external and internal sources. The Toxicologist 2006;90:336. R831709 (2005)
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Abstract Refinement of a high-throughput 2D-PAGE technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants TOXICOLOGICAL SCIENCES Hong S, Sidhu JS, Kim E, Faustman EM Hong S, Sidhu JS, Kim E, Faustman EM. Refinement of a high-throughput 2D-PAGE technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. The Toxicologist: Supplement to Toxicological Sciences 2003;72(Supplement 1):732. R831709 (2007)
Abstract Refinement of high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. TOXICOLOGIST Hong S, Sidhu J Hong S, Sidhu J. Refinement of high-throughput 2D-Page technique for the evaluation of ubiquitin-conjugated protein status induced by developmental toxicants. The Toxicologist 2003;72:732. R831709 (2005)
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Abstract Attempted reconciliation of predicted children's exposures to organophosphate pesticides with measured metabolite levels in urine. EPIDEMIOLOGY Kissel J, Kedan G, Wawrukiewicz A, Fenske RA Kissel J, Kedan G, Wawrukiewicz A, Fenske RA. Attempted reconciliation of predicted children's exposures to organophosphate pesticides with measured metabolite levels in urine. Epidemiology 1999;10(4):S110. R826886C004 (2001)
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Abstract Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. THE TOXICOLOGIST Robinson J, Yu X, Sidhu J, Hong S, Kim E, Faustman EM Robinson J, Yu X, Sidhu J, Hong S, Kim E, Faustman EM. Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. The Toxicologist 2005;84(S1):2257. R831709C001 (2005)
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Abstract Differential impact of cadmium on gene expression during neuralation in the C57BL/6 and SWV. BIRTH DEFECTS RESEARCH PART A< Robinson J, Yu X, Hong S, Kim E, Sullivan R, Griffith W, Faustman E Robinson J, Yu X, Hong S, Kim E, Sullivan R, Griffith W, Faustman E. Differential impact of cadmium on gene expression during neuralation in the C57BL/6 and SWV. Birth Defects Research Part A 2006;76(5):392. R831709 (2005)
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Abstract Examination of arsenic-induced alterations in cell cycle progression and global gene expression in p53 transgenic mouse embryonic fibroblasts. TOXICOLOGIST Robinson J, Yu X, Gribble E, Hong S, Kim E, Sidhu J, Faustman E Robinson JF, Yu X, Gribble EJ, Hong S, Kim E, Sidhu JS, Faustman EM. Examination of arsenic-induced alterations in cell cycle progression and global gene expression in p53 transgenic mouse embryonic fibroblasts. The Toxicologist 2006;90:91-92. R831709 (2005)
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Abstract Methylmercury induces differential ubiquitin conjugated protein levels in p53 variant mouse embryonal biroblasts. TOXICOLOGIST Sidhu J, Hong S Sidhu J, Hong S. Methylmercury induces differential ubiquitin conjugated protein levels in p53 variant mouse embryonal biroblasts. The Toxicologist 2003;72:323. R831709 (2005)
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Abstract Asbestos and radiation as combined exposures in pulmonary fibrosis. TOXICOLOGIST Takaro T, Griffith W Takaro T, Griffith W. Asbestos and radiation as combined exposures in pulmonary fibrosis. The Toxicologist 2003;72:220. R831709 (2005)
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Abstract Integrative analysis of genome-wide gene expression and pathway mapping in mouse embryonic fibroblast (MEF) exposed to cadmium, arsenic, and methylmercury: induction of oxidative stress, disruption of ubiquitin-proteasome system and cell cycle regulation. THE TOXICOLOGIST Yu X, Sidhu J, Robinson J, Hong S, Faustman EM Yu X, Sidhu J, Robinson J, Hong S, Faustman EM. Integrative analysis of genome-wide gene expression and pathway mapping in mouse embryonic fibroblast (MEF) exposed to cadmium, arsenic, and methylmercury: induction of oxidative stress, disruption of ubiquitin-proteasome system and cell cycle regulation. The Toxicologist 2005;84(S1):1155. R831709C001 (2005)
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Abstract Functional interpretation of dose and time-dependent microarray data: quantitative integration of GO ontology analysis for toxicology and risk assessment. TOXICOLOGIST Yu X, Griffith W, Hanspers K, Robinson J, Faustman EM Yu X, Griffith W, Hanspers K, Robinson J, Faustman EM. Functional interpretation of dose-and time-dependent microarray data: quantitative integration of GO ontology analysis for toxicology and risk assessment. The Toxicologist 2006;90(1):182-183. R831709 (2005)
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Abstract A systems based approach to identify potential signalling pathways during gonad development from microarray data. BIRTH DEFECTS RESEARCH PART A Yu X, Griffith W, Hanspers K, Ong H, Faustman E Yu X, Griffith WC, Hanspers K, Ong H, Faustman EM. A system based approach to identify potential signalling pathways during gonad development from microarray data. Birth Defects Research Part A 2006;76(5):339. R831709 (2005)
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Book Gene-Environment Interactions: Fundamentals of Ecogenetics. None Costa LG, Eaton DL, eds. Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., March 2006, 557 pp. R831709 (2006)
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Book Chapter Paraoxonase polymorphisms and susceptibility to organophosphate pesticides. None Battuello K, Furlong C, Fenske R, Austin MA, Burke W Battuello K, Furlong C, Fenske R, Austin MA, Burke W. Paraoxonase polymorphisms and susceptibility to organophosphate pesticides. In:Khoury MJ, Little J, Burke W, eds. Human Genome Epidemiology:A Scientific Foundation for Using Genetic Information To Improve Health and Prevent Disease. Oxford, UK:Oxford University Press, 2004, Chapter 18, pp. 305-321. R831709 (2005)
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Book Chapter PON1 polymorphisms. None Brophy VH, Jarvik GP, Furlong CE Brophy VH, Jarvik GP, Furlong CE. PON1 polymorphisms. In: Costa LG, Furlong CE, eds. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Boston, MA: Springer, 2002, Chapter 3, pp. 53-77. R826886 (2000)
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Book Chapter PON1 polymorphisms. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. None Brophy VH, Jarvik PG Brophy VH, Jarvik PG. PON1 polymorphisms. In: Costa L, Furlong C, eds. Paraoxonase (PON1) in Health and Disease: Basic and Clinical Aspects. Norwell, MA: Kluwer Academic Publishers, 2002, Chapter 3, pp. 53-77. R831709 (2005)
Book Chapter PON1 and organophosphate toxicity. None Costa LG, Li W-F, Richter RJ, Shih DM, Lucis AJ, Furlong CE Costa LG, Li W-F, Richter RJ, Shih DM, Lucis AJ, Furlong CE. PON1 and organophosphate toxicity. In: Costa LG, Furlong CE, eds. Paraoxonase(PON1) in Health and Disease: Basic and Clinical Aspects. Boston, MA: Springer, 2002, Chapter 8, pp. 165-183. R826886 (2000)
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Book Chapter Paraoxonase (PON1) gene polymorphisms. None Costa LG, Furlong CE Costa LG, Furlong CE. Paraoxonase (PON1) gene polymorphisms. In: Fuchs J, Podda M, eds. Encyclopedia of Medical Genomics and Proteomics. New York, NY: Taylor & Francis, 2004, pp. 965-969. R831709 (2007)
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Book Chapter Paraoxonase polymorphisms and toxicity of organophosphates. None Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphate and Carbamate Compounds. Amsterdam: Elsevier, Inc., December 2005, pp. 247-255. R831709 (2007)
Book Chapter Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. None Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase (PON1) polymorphisms and toxicity of organophosphates. In: Gupta RC, ed. Toxicology of Organophosphates & Carbamate Compounds. San Diego, CA: Academic Press, 2005, Chapter 18, pp. 247-255. R831709 (2005)
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Book Chapter Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. None Costa LG, Cole TB, Geiss GK, Furlong CE Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 9, pp. 159-177. R831709 (2005)
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Book Chapter Receptors and ion channels. None Costa LG Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions:Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 11, pp. 197-210. R831709 (2005)
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Book Chapter Toxic effects of pesticides. None Costa LG Costa LG. Toxic effects of pesticides. In: Klaassen CD, ed. Casarett & Doull’s Toxicology: The Basic Science of Poisons, 7th Edition. New York, NY: McGraw-Hill, 2007, Chapter 22, pp. 883-932. R831709 (2005)
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Book Chapter Chapter 11. None Costa LG Costa LG. Receptors and ion channels. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. R831709 (2006)
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Book Chapter Chapter 9. None Costa LG, Cole TB, Geiss GK, Furlong CE Costa LG, Cole TB, Geiss GK, Furlong CE. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, 2006. R831709 (2006)
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Book Chapter Facilitating regulatory design and stakeholder participation: the FERET template with an application to the Clean Air Act. None Farrow, RS, Wong E, Ponce RA, Faustman EM, Zerbe RO Farrow, RS, Wong E, Ponce RA, Faustman EM, Zerbe RO. Facilitating regulatory design and stakeholder participation: the FERET template with an application to the Clean Air Act. In: Fischbeck PS, Farrow RS, eds. Improving Regulation: Cases in Environment, Health and Safety. Washington, DC: Resources for the Future Press, 2001, Chapter 19, pp. 429-442. R831709 (2005)
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Book Chapter Experimental approaches to evaluate mechanisms of developmental toxicity. None Faustman EM, Gohlke JM, Ponce RA, Lewandowski TA, Seeley MR, Whittaker SG, Griffith WC Faustman EM, Gohlke JM, Ponce RA, Lewandowski TA, Seeley MR, Whittaker SG, Griffith WC. Experimental approaches to evaluate mechanisms of developmental toxicity. In: Hood RD, ed. Developmental and Reproductive Toxicology: A Practical Approach, 2nd edition. Boca Raton, FL: CRC Press, Inc., 2005, Chapter 2, pp. 15-60. R831709 (2005)
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Book Chapter Gene-Environment Interactions: Fundamentals of Ecogenetics None Faustman EM, Omenn GS Faustman EM, Omenn GS. Risk assesssment and the impact of ecogenetics. In:Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics, Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 25, pp. 427-450. R831709 (2005)
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Book Chapter Understanding the significance of genetic variability in the human PON1 gene. None Furlong CE, Li W-F, Cole TB, Jampsa R, Richter RJ, Jarvik GP, Shih DM, Tward A, Lusis AJ, Costa LG Furlong CE, Li W-F, Cole TB, Jampsa R, Richter RJ, Jarvik GP, Shih DM, Tward A, Lusis AJ, Costa LG. Understanding the significance of genetic variability in the human PON1 gene. In: Valdes JJ, Sekowski JW, eds. Toxicogenomics and Proteomics, NATO Science Series: Life and Behavioural Sciences, Volume 356. Amsterdam, Netherlands: IOS Press, 2004. R831709 (2007)
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Book Chapter Neurodegenerative diseases. None Kelada SN, Checkoway H, Costa LG Kelada SN, Checkoway H, Costa LG. Neurodegenerative diseases. In: Costa LG, Eaton DL, eds. Gene-Environment Interactions: Fundamentals of Ecogenetics. Hoboken, NJ: John Wiley & Sons, Inc., 2006, Chapter 15, pp. 253-269. R831709 (2005)
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Book Chapter Identifying mechanisms of developmental toxicity: application of tools from molecular biology. None Kirchner SC, Faustman EM Kirchner SC, Faustman EM. Identifying mechanisms of developmental toxicity: application of tools from molecular biology. In: Puga A, Wallace KB, eds. Molecular Biology of the Toxic Response. London, UK: Taylor and Francis Publishers, 1999, Chapter 24, pp. 411-437. R831709 (2005)
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Book Chapter Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. None Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE. Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. In: Maines M, Costa LG, Hodgson E, Reed DJ, eds. Current Protocols in Toxicology. New York, NY: John Wiley & Sons, Inc., 2004, pp. Unit 4.12. R831709C002 (2004)
Journal Article Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs None Bal-Price AK, Sunol C, Weiss DG, van Vliet E, Westerink RHS, Costa LG Bal-Price AK, Sunol C, Weiss DG, van Vliet E, Westerink RHS, Costa LG . Application of in vitro neurotoxicity testing for regulatory purposes:Symposium III summary and research needs. Neurotoxicology 2008;29(3):520-531. R831709 (2007)
Journal Article Human variability in mercury toxicokinetics and steady state biomarker ratios. ENVIRONMENTAL RESEARCH Bartell SM, Ponce RA, Sanga RN, Faustman EM Bartell SM, Ponce RA, Sanga RN, Faustman EM. Human variability in mercury toxicokinetics and steady state biomarker ratios. Environmental Research 2000;84(2):127-132. R831709 (2007)
Journal Article Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology and Diabetes 2007;115(4):221-228. R831709 (2005)
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Journal Article Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. AMERICAN JOURNAL OF HUMAN GENETICS Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE Brophy VH, Jampsa RL, Clendenning JB, McKinstry LA, Jarvik GP, Furlong CE. Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression. American Journal of Human Genetics 2001;68(6):1428-1436. R826886 (2000)
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Journal Article Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells. DEVELOPMENTAL NEUROSCIENCE Burry M, Guizzetti M, Oberdoerster J, Costa LG Burry M, Guizzetti M, Oberdoerster J, Costa LG. Developmental neurotoxicity of toluene:in vivo and in vitro effects on astroglial cells. Developmental Neuroscience 2003;25(1):14-19. R831709 (2005)
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Journal Article Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. TOXICOLOGICAL SCIENCES Caughlan A, Newhouse K, Namgung U, Xia Z Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicological Sciences 2004;78(1):125-134. R831709 (2007)
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Journal Article Expression of human paraoxonase (PON1) during development. PHARMACOGENETICS Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE Cole TB, Jampsa RL, Walter BJ, Arndt TL, Richter RJ, Shih DM, Tward A, Lusis AJ, Jack RM, Costa LG, Furlong CE. Expression of human paraoxonase (PON1) during development. Pharmacogenetics 2003;13(6):357-364. R831709 (2005)
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Journal Article Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. PHARMACOGENETICS AND GENOMICS Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE. Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenetics and Genomics 2005;15(8):589-598. R831709 (2005)
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Journal Article The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. None Cole TB, Jansen K, Park S, Li W-F, Furlong CE, Costa LG Cole TB, Jansen K, Park S, Li W-F, Furlong CE, Costa LG. The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. Advances in Experimental Medicine and Biology 2010;660:47-60. R831709 (2007)
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Journal Article Agricultural task and exposure to organophosphate pesticides among farmworkers. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Strong L, Griffith WC, Islas I Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Agricultural task and exposure to organophosphate pesticides among farmworkers. Environmental Health Perspectives 2004;112(2):142-147. R831709 (2005)
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Journal Article Children’s exposure to OP pesticides: response to Fenske et al. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Griffith WC Coronado GD, Thompson B, Griffith WC. Children's exposure to OP pesticides:response to Fenske et al. Environmental Health Perspectives 2004;112(15):A866 (correspondence). R831709 (2005)
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Journal Article Children's exposure to OP pesticides: response to Fenske et al ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Griffith WC Coronado GD, Thompson B, Griffith WC. Children's exposure to OP pesticides: response to Fenske et al. Environmental Health Perspectives 2004;112(15):A866-A866. R831709 (2007)
Journal Article Activities and organophosphate exposures: response. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Thompson B, Strong L, Griffith WC, Islas I Coronado GD, Thompson B, Strong L, Griffith WC, Islas I. Activities and organophosphate exposures: response. Environmental Health Perspectives 2004;112(13):A725-A726 (correspondence). R831709 (2005)
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Journal Article Organophosphate pesticide exposure and work in pome fruit: evidence for the take-home pesticide pathway. ENVIRONMENTAL HEALTH PERSPECTIVES Coronado GD, Vigoren EM, Thompson B, Griffith WC, Faustman EM Coronado GD, Vigoren EM, Thompson B, Griffith WC, Faustman EM. Organophosphate pesticide exposure and work in pome fruit:evidence for the take-home pesticide pathway. Environmental Health Perspectives 2006;114(7):999-1006. R831709 (2005)
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Journal Article Organophosphate pesticide exposure among pome and non-pome farmworkers: a subgroup analysis of a community randomized trial. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B Coronado GD, Vigoren EM, Griffith WC, Faustman EM, Thompson B. Organophosphate pesticide exposure among pome and non-pome farmworkers:a subgroup analysis of a community randomized trial. Journal of Occupational and Environmental Medicine 2009;51(4):500-509. R831709 (2007)
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Journal Article Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. BIOMARKERS Costa LG, Richter RJ, Li W-F, Cole T, Guizzetti M, Furlong CE Costa LG, Richter RJ, Li W-F, Cole T, Guizzetti M, Furlong CE. Paraoxonase (PON1) as a biomarker of susceptibility for organophosphate toxicity. Biomarkers 2003;8(1):1-12. R826886 (2000)
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Journal Article Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. ANNUAL REVIEW OF MEDICINE Costa LG, Cole TB, Jarvik GP, Furlong CE Costa LG, Cole TB, Jarvik GP, Furlong CE. Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annual Review of Medicine 2003;54:371-392. R826886 (2000)
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Journal Article Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates. Clinical Toxicology 2003;41(1):37-45. R831709 (2005)
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Journal Article Developmental neuropathology of environmental agents. ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY Costa LG, Aschner M, Vitalone A, Syversen T, Soldin OP Costa LG, Aschner M, Vitalone A, Syversen T, Soldin OP. Developmental neuropathology of environmental agents. Annual Review of Pharmacology and Toxicology 2004;44:87-110. R831709 (2005)
R831709 (2007)
Journal Article Modulation of paraoxonase (PON1) activity. BIOCHEMICAL PHARMACOLOGY Costa LG, Vitalone A, Cole TB, Furlong CE Costa LG, Vitalone A, Cole TB, Furlong CE. Modulation of paraoxonase (PON1) activity. Biochemical Pharmacology 2005;69(4):541-550. R831709 (2005)
R831709 (2007)
R831709C002 (2004)
Journal Article Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. CLINICA CHIMICA ACTA Costa LG, Cole TB, Vitalone A, Furlong CE Costa LG, Cole TB, Vitalone A, Furlong CE. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clinica Chimica Acta 2005;352(1-2):37-47. R831709 (2005)
R831709 (2007)
R831709C002 (2004)
Journal Article Paraoxonase (PON1): from toxicology to cardiovascular medicine. ACTA BIOMEDICA ATENEI PARMENSIS Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Paraoxonase (PON1): from toxicology to cardiovascular medicine. Acta Biomedica 2005;76(Suppl 2):50-57. R831709 (2005)
Journal Article Current issues in organophosphate toxicology. CLINICA CHIMICA ACTA Costa LG Costa LG. Current issues in organophosphate toxicology. Clinica Chimica Acta 2006;366(1-2):1-13. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C001 (2006)
Journal Article Gene-environment interactions: paraoxonase (PON1) and sensitivity to organophosphate toxicity. LABMEDICINE Costa LG, Cole TB, Furlong CE Costa LG, Cole TB, Furlong CE. Gene-environment interactions:paraoxonase (PON1) and sensitivity to organophosphate toxicity. LabMedicine 2006;37(2):109-113. R831709 (2005)
R831709 (2007)
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R831709C002 (2007)
Journal Article Neurotoxicity of pesticides: a brief review. FRONTIERS IN BIOSCIENCE Costa LG, Giordano G, Guizzetti M, Vitalone A Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Frontiers in Bioscience 2008;13(4):1240-1249. R831709 (2005)
R831709 (2007)
R831709C001 (2007)
R831709C002 (2007)
Journal Article The application of genetic information for regulatory standard setting under the clean air act: a decision-analytic approach. RISK ANALYSIS Cullen AC, Corrales MA, Kramer CB, Faustman EM Cullen AC, Corrales MA, Kramer CB, Faustman EM. The application of genetic information for regulatory standard setting under the clean air act:a decision-analytic approach. Risk Analysis 2008;28(4):877-890. R831709 (2007)
R832733 (Final)
Journal Article Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. ENVIRONMENTAL HEALTH PERSPECTIVES Curl CL, Fenske RA, Elgethun K Curl CL, Fenske RA, Elgethun K. Organophosphorus pesticide exposure of urban and suburban preschool children with organic and conventional diets. Environmental Health Perspectives 2003;111(3):377-382. R831709 (2005)
R831709 (2007)
Journal Article A framework for assessing risks to children from exposure to environmental agents. ENVIRONMENTAL HEALTH PERSPECTIVES Daston G, Faustman E, Ginsberg G, Fenner-Crisp P, Olin S, Sonawane B, Bruckner J, Breslin W, McLaughlin TJ Daston G, Faustman E, Ginsberg G, Fenner-Crisp P, Olin S, Sonawane B, Bruckner J, Breslin W, McLaughlin TJ. A framework for assessing risks to children from exposure to environmental agents. Environmental Health Perspectives 2004;112(2):238-256. R831709 (2007)
R831709C001 (2004)
Journal Article Nuclear waste transportation: case studies of identifying stakeholder risk information needs. ENVIRONMENTAL HEALTH PERSPECTIVES Drew CH, Grace DA, Silbernagel SM, Hemmings ES, Smith A, Griffith WC, Takaro TK, Faustman EM Drew CH, Grace DA, Silbernagel SM, Hemmings ES, Smith A, Griffith WC, Takaro TK, Faustman EM. Nuclear waste transportation:case studies of identifying stakeholder risk information needs. Environmental Health Perspectives 2003;111(3):263-272. R831709 (2005)
R831709 (2007)
Journal Article Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. CRITICAL REVIEWS IN TOXICOLOGY Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Critical Reviews in Toxicology 2008;38(Supplement 2):1-125. R831709 (2007)
Journal Article Time-location analysis for exposure assessment studies of children using a novel global positioning system instrument. ENVIRONMENTAL HEALTH PERSPECTIVES Elgethun K, Fenske RA, Yost MG, Palcisko GJ Elgethun K, Fenske RA, Yost MG, Palcisko GJ. Time-location analysis for exposure assessment studies of children using a novel global positioning system instrument. Environmental Health Perspectives 2003;111(1):115-122. R826886 (2000)
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Journal Article Comparison of global positioning system (GPS) tracking and parent-report diaries to characterize children's time-location patterns. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY Elgethun K, Yost MG, Fitzpatrick CTE, Nyerges TL, Fenske RA Elgethun K, Yost MG, Fitzpatrick CTE, Nyerges TL, Fenske RA. Comparison of global positioning system (GPS) tracking and parent-report diaries to characterize children's time-location patterns. Journal of Exposure Science and Environmental Epidemiology 2007;17(2):196-206. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C004 (2006)
R831709C004 (2007)
Journal Article Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. ENVIRONMENTAL HEALTH PERSPECTIVES Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT Eskenazi B, Harley K, Bradman A, Weltzien E, Jewell NP, Barr DB, Furlong CE, Holland NT. Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population. Environmental Health Perspectives 2004;112(10):1116-1124. R831709 (2007)
R831709C002 (2004)
R831710 (2004)
R831710 (2005)
R831710 (Final)
R831710C001 (2004)
Journal Article Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. ENVIRONMENTAL HEALTH PERSPECTIVES Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K Eskenazi B, Gladstone EA, Berkowitz GS, Drew CH, Faustman EM, Holland NT, Lanphear B, Meisel SJ, Perera FP, Rauh VA, Sweeney A, Whyatt RM, Yolton K. Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1419-1429. R827027 (2002)
R829389 (2003)
R829389 (2004)
R829389 (2005)
R829389 (Final)
R829390 (2005)
R829390 (Final)
R829390C002 (2005)
R831709 (2005)
R831709C001 (2004)
R831710 (2005)
R831710 (Final)
R831710C001 (2006)
R831710C002 (2006)
R831711 (2005)
R831711 (2006)
R831711 (2007)
R831711 (Final)
R831711C001 (2006)
R831711C002 (2004)
R831711C002 (2006)
R831711C003 (2006)
R832141 (2005)
R832141 (2007)
R832141 (Final)
Journal Article Modeling developmental processes in animals: applications in neurodevelopmental toxicology. None Faustman EM, Gohlke J, Judd NL, Lewandowski TA, Bartell SM, Griffith WC Faustman EM, Gohlke J, Judd NL, Lewandowski TA, Bartell SM, Griffith WC. Modeling developmental processes in animals:applications in neurodevelopmental toxicology. Environmental Toxicology and Pharmacology 2005;19(3):615-624. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C001 (2004)
R831709C001 (2005)
R831709C001 (2006)
Journal Article Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers: an analysis of recent studies in Washington State. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC Fenske RA, Lu C, Curl CL, Shirai JH, Kissel JC. Biologic monitoring to characterize organophosphorus pesticide exposure among children and workers:an analysis of recent studies in Washington State. Environmental Health Perspectives 2005;113(11):1651-1657. R831709 (2005)
R831709 (2007)
Journal Article Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. ENVIRONMENTAL HEALTH PERSPECTIVES Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB Fenske RA, Bradman A, Whyatt RM, Wolff MS, Barr DB. Lessons learned for the assessment of children's pesticide exposure: critical sampling and analytical issues for future studies. Environmental Health Perspectives 2005;113(10):1455-1462. R827027 (2002)
R828609 (Final)
R831709 (2005)
R831709 (2007)
R831710 (2004)
R831710 (2005)
R831710 (Final)
R831711 (2004)
R831711 (2005)
R831711 (2006)
R831711 (2007)
R831711 (Final)
R831711C001 (2006)
R831711C002 (2006)
R831711C003 (2006)
R832141 (2006)
R832141 (2007)
R832141 (Final)
Journal Article Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. NEUROTOXICOLOGY Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity:genetic and temporal determinants. Neurotoxicology 2005;26(4):651-659. R831709 (2005)
R831709 (2007)
R831709C002 (2004)
Journal Article Paraoxonase 1 (PON1) status and risk of insecticide exposure. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. Paraoxonase 1 (PON1) status and risk of insecticide exposure. Journal of Biochemical and Molecular Toxicology 2005;19(3):182-183. R831709 (2005)
R831709 (2007)
R831709C002 (2005)
Journal Article PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. PHARMACOGENETICS AND GENOMICS Furlong CE, Holland N, Richter RJ, Bradman A, Ho A, Eskenazi B Furlong CE, Holland N, Richter RJ, Bradman A, Ho A, Eskenazi B. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics 2006;16(3):183-190. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C002 (2006)
R831710 (2004)
R831710 (2005)
R831710 (Final)
R831710C001 (2007)
R831710C003 (2006)
R831710C003 (2007)
Journal Article Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY Furlong CE Furlong CE. Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. Journal of Biochemical and Molecular Toxicology 2007;21(4):197-205. R831709 (2005)
R831709 (2007)
Journal Article Human PON1, a biomarker of risk of disease and exposure. None Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP. Human PON1, a biomarker of risk of disease and exposure. Chemico-Biological Interactions 2010;187(1-3):355-361. R831709 (2007)
R834514 (2011)
R834514 (2012)
R834514 (2013)
Journal Article Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. FREE RADICAL BIOLOGY AND MEDICINE Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vliet P, Deeb S Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vliet P, Deeb S. Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. Free Radical Biology and Medicine 2008;44(6):1075-1087. R831709 (2005)
R831709 (2007)
R832733 (Final)
Journal Article Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. TOXICOLOGY AND APPLIED PHARMACOLOGY Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology 2007;219(2-3):181-189. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C001 (2006)
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R831709C002 (2007)
Journal Article Manganese inhibits the ability of astrocytes to promote neuronal differentiation TOXICOLOGY AND APPLIED PHARMACOLOGY Giordano G, Pizzurro D, VanDeMark KL, Guizzetti M, Costa LG Giordano G, Pizzurro D, VanDeMark KL, Guizzetti M, Costa LG. Manganese inhibits the ability of astrocytes to promote neuronal differentiation. Toxicology and Applied Pharmacology 2009; 240(2):226-235. R831709 (2007)
Journal Article The role of cell death during neocortical neurogenesis and synaptogenesis: implications from a computational model for the rat and mouse. DEVELOPMENTAL BRAIN RESEARCH Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. The role of cell death during neocortical neurogenesis and synaptogenesis:implications from a computational model for the rat and mouse. Developmental Brain Research 2004;151(1-2):43-54. R831709 (2005)
R831709 (2007)
R831709C001 (2004)
Journal Article A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. TOXICOLOGY SCIENCE Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity. Toxicological Sciences 2005;86(2):470-484. R831709 (2004)
R831709 (2005)
R831709 (2007)
R831709C001 (2005)
Journal Article Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. None Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. Cerebral Cortex 2007;17(10):2433-2442. R831709 (2005)
R831709 (2007)
R832733 (Final)
Journal Article Computational models of ethanol-induced neurodevelopmental toxicity across species: implications for risk assessment. BIRTH DEFECTS RESEARCH PART B. DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational models of ethanol-induced neurodevelopmental toxicity across species:implications for risk assessment. Birth Defects Research Part B. Developmental and Reproductive Toxicology 2008;83(1):1-11. R831709 (2007)
R832733 (Final)
Journal Article The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53-dependent. BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY Gribble EJ, Hong SW, Faustman EM Gribble EJ, Hong SW, Faustman EM. The magnitude of methylmercury-induced cytotoxicity and cell cycle arrest is p53-dependent. Birth Defects Research Part A:Clinical and Molecular Teratology 2005;73(1):29-38. R831709 (2005)
R831709 (2007)
R831709C001 (2004)
Journal Article Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. TOXICOLOGY Guizzetti M, Pathak S, Giordano G, Costa LG Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology 2005;215(3):182-190. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C001 (2005)
R831709C001 (2006)
R831709C002 (2006)
Journal Article Modulation of neuritogenesis by astrocyte muscarinic receptors. None Guizzetti M, Moore NH, Giordano G, Costa LG Guizzetti M, Moore NH, Giordano G, Costa LG. Modulation of neuritogenesis by astrocyte muscarinic receptors. Journal of Biological Chemistry 2008;283(46):31884-31897. R831709 (2007)
Journal Article Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. GLIA Guizzetti M, Moore NH, Giordano G, VanDeMark KL, Costa LG Guizzetti M, Moore NH, Giordano G, VanDeMark KL, Costa LG. Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors. Glia 2010;58(12):1395-1406. R831709 (2007)
R834514 (2011)
R834514 (2012)
R834514 (2013)
Journal Article ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. JOURNAL OF BIOLOGICAL CHEMISTRY Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. Journal of Biological Chemistry 277(51):49577-49584. R831709 (2005)
R831709 (2007)
Journal Article Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. ENVIRONMENTAL HEALTH PERSPECTIVES Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B Holland N, Furlong C, Bastaki M, Richter R, Bradman A, Huen K, Beckman K, Eskenazi B. Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Environmental Health Perspectives 2006;114(7):985-991. R831709 (2005)
R831709 (2006)
R831709 (2007)
R831709C002 (2006)
R831710 (2004)
R831710 (2005)
R831710 (Final)
R831710C001 (2007)
R831710C003 (2006)
R832734 (2006)
R832734 (2007)
R832734 (Final)
Journal Article Validation of PON1 enzyme activity assays for longitudinal studies. CLINICA CHIMA ACTA Huen K, Richter R, Furlong C, Eskenazi B, Holland N Huen K, Richter R, Furlong C, Eskenazi B, Holland N. Validation of PON1 enzyme activity assays for longitudinal studies. Clinica Chimica Acta 2009;402(1-2):67-74. R831709 (2007)
R831710 (Final)
R832734 (2009)
R832734 (Final)
R834513 (2010)
R834513 (2011)
R834513 (Final)
Journal Article Community-based participatory research: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. ENVIRONMENTAL HEALTH PERSPECTIVES Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S Israel BA, Parker EA, Rowe Z, Salvatore A, Minkler M, Lopez J, Butz A, Mosley A, Coates L, Lambert G, Potito PA, Brenner B, Rivera M, Romero H, Thompson B, Coronado G, Halstead S. Community-based participatory research:lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1463-1471. R826710 (Final)
R829391 (2004)
R829391 (2005)
R829391 (2006)
R829391C005 (2006)
R831709 (2005)
R831709 (2007)
R831709C003 (2005)
R831709C003 (2006)
R831710 (2004)
R831710 (2005)
R831710 (Final)
R831710C001 (2006)
R831710C002 (2006)
R831710C004 (2006)
R831711 (2005)
R831711 (2006)
R831711 (2007)
R831711 (Final)
R831711C001 (2006)
R831711C002 (2006)
R831711C003 (2006)
R832139 (2006)
Journal Article Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. PHARMACOGENETICS Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE Jarvik GP, Jampsa R, Richter RJ, Carlson CS, Rieder MJ, Nickerson DA, Furlong CE. Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. Pharmacogenetics 2003;13(5):291-295. R831709 (2005)
R831709 (2007)
R831709C002 (2004)
Journal Article A model for optimization of biomarker testing frequency to minimize disease and cost: example of beryllium sensitization testing. RISK ANALYSIS Judd NL, Griffith WC, Takaro T, Faustman EM Judd NL, Griffith WC, Takaro T, Faustman EM. A model for optimization of biomarker testing frequency to minimize disease and cost:example of beryllium sensitization testing. Risk Analysis 2003; 23(6):1211-1220. R831709 (2005)
R831709 (2007)
Journal Article Challenges in defining background levels for human and ecological risk assessments. HUMAN AND ECOLOGICAL RISK ASSESSMENT Judd NL, Karr JR, Griffith WC, Faustman EM Judd NL, Karr JR, Griffith WC, Faustman EM. Challenges in defining background levels for human and ecological risk assessments.Human and Ecological Risk Assessment:An International Journal 2003; 9(7):1623-1632. R831709 (2005)
R831709 (2007)
Journal Article Assessment of PCB congener analytical methods: do they meet risk assessment needs? None Judd NL, Griffith WC, Kalman DA, Faustman EM Judd NL, Griffith WC, Kalman DA, Faustman EM. Assessment of PCB congener analytical methods:do they meet risk assessment needs? Archives of Environmental Contamination and Toxicology 2003; 44(1):132-139. R831709 (2005)
R831709 (2007)
Journal Article Consideration of cultural and lifestyle factors in defining susceptible populations for environmental disease. TOXICOLOGY Judd NL, Griffith WC, Faustman EM Judd NL, Griffith WC, Faustman EM. Consideration of cultural and lifestyle factors in defining susceptible populations for environmental disease. Toxicology 2004;198(1-3):121-133. R831709 (2005)
R831709 (2007)
Journal Article Contribution of PCB exposure from fish consumption to total dioxin-like dietary exposure. REGULATORY TOXICOLOGY AND PHARMACOLOGY Judd N, Griffith WC, Faustman EM Judd N, Griffith WC, Faustman EM. Contribution of PCB exposure from fish consumption to total dioxin-like dietary exposure. Regulatory Toxicology and Pharmacology 2004;40(2):125-135. R831709 (2005)
R831709 (2007)
Journal Article Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth Jr WT, Furlong CE, Javrik GP, Swanson PD Kelada SN, Costa-Mallen P, Checkoway H, Viernes HA, Farin FM, Smith-Weller T, Franklin GM, Costa LG, Longstreth Jr WT, Furlong CE, Javrik GP, Swanson PD. Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry 2003;74(4):546-547. R831709 (2005)
R831709 (2007)
R831709C002 (2004)
Journal Article Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease. NEUROSCIENCE LETTERS Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth Jr WT, Checkoway H Kelada SN, Stapleton PL, Farin FM, Bammler TK, Eaton DL, Smith-Weller T, Franklin GM, Swanson PD, Longstreth Jr WT, Checkoway H. Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's disease. Neuroscience Letters 2003;337(1):5-8. R831709 (2005)
R831709 (2007)
Journal Article Comparison of organophosphorus pesticide metabolite levels in single and multiple daily urine samples collected from preschool children in Washington State. JOURNAL OF EXPOSURE ANALYSIS AND ENVIRONMENTAL EPIDEMIOLOGY Kissel JC, Curl CL, Kedan G, Lu C, Griffith W, Barr DB, Needham LL, Fenske RA Kissel JC, Curl CL, Kedan G, Lu C, Griffith W, Barr DB, Needham LL, Fenske RA. Comparison of organophosphorus pesticide metabolite levels in single and multiple daily urine samples collected from preschool children in Washington State. Journal of Exposure Analysis and Environmental Epidemiology 2005;15(2):164-171. R831709 (2005)
R831709 (2007)
Journal Article Evaluation of the equilibrium, dynamic, and hybrid aerosol modeling approaches. AEROSOL SCIENCE AND TECHNOLOGY Koo B, Gaydos TM, Pandis SN Koo B, Gaydos TM, Pandis SN. Evaluation of the equilibrium, dynamic, and hybrid aerosol modeling approaches. Aerosol Science and Technology 2003;37(1):53-64. R826371 (Final)
R826371C005 (Final)
R831709 (2007)
R831709C003 (2004)
Journal Article Report: Community-based, participatory research in Lawrence, Massachusetts, flags environmental health hazards and fuels education and action SCIENCE COMMUNICATION Latowsky G Latowsky G. Report: Community-based, participatory research in Lawrence, Massachusetts, flags environmental health hazards and fuels education and action. Science Communication 2003;25(2):204-208. R828596 (2004)
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R831709 (2007)
Journal Article Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. DEVELOPMENTAL BRAIN RESEARCH Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Changes in cell cycle parameters and cell number in the rat midbrain during organogenesis. Developmental Brain Research 2003;141(1-2):117-128. R831709 (2005)
R831709 (2007)
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Journal Article Effect of methylmercury on midbrain cell proliferation during organogenesis: potential cross-species differences and implications for risk assessment. TOXICOLOGICAL SCIENCES Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM Lewandowski TA, Ponce RA, Charleston JS, Hong S, Faustman EM. Effect of methylmercury on midbrain cell proliferation during organogenesis:potential cross-species differences and implications for risk assessment. Toxicological Sciences 2003;75(1):124-133. R831709 (2005)
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Journal Article Workplace exposures and protective practices of Hispanic warehouse workers. JOURNAL OF IMMIGRANT AND MINORITY HEALTH Livaudais JC, Thompson B, Islas I, Ibarra G, Anderson J, Coronado GD Livaudais JC, Thompson B, Islas I, Ibarra G, Anderson J, Coronado GD. Workplace exposures and protective practices of Hispanic warehouse workers. Journal of Immigrant and Minority Health 2009;11(2):122-130. R831709 (2007)
Journal Article Seasonal variation in fruit and vegetable consumption in a rural agricultural community. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION Locke E, Coronado GD, Thompson B, Kuniyuki A Locke E, Coronado GD, Thompson B, Kuniyuki A. Seasonal variation in fruit and vegetable consumption in a rural agricultural community. Journal of the American Dietetic Association 2009;109(1):45-51. R831709 (2007)
Journal Article Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. MOLECULAR REPRODUCTION AND DEVELOPMENT Luderer U, Diaz D, Faustman EM, Kavanagh TJ Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Molecular Reproduction and Development 2003;65(3):254-261. R831709 (2005)
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Journal Article Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos TOXICOLOGY AND APPLIED PHARMACOLOGY Moreira EG, Yu X, Robinson JF, Griffith W, Hong SW, Beyer RP, Bammler TK, Faustman EM Moreira EG, Yu X., Robinson JF, Griffith W, Hong SW, Beyer RP, Bammler TK, Faustman EM. Toxicogenomic profiling in maternal and fetal rodent brains following gestational exposure to chlorpyrifos. Toxicology and Applied Pharmacology 2010;245(3):310-325. R831709 (2007)
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R834514C003 (Final)
Journal Article The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization. ATMOSPHERIC ENVIRONMENT Ramaprasad J, Tsai M-Y, Elgethun K, Hebert VR, Felsot A, Yost MG, Fenske RA Ramaprasad J, Tsai M-Y, Elgethun K, Hebert VR, Felsot A, Yost MG, Fenske RA. The Washington aerial spray drift study: assessment of off-target organophosphorus insecticide atmospheric movement by plant surface volatilization. Atmospheric Environment 2004;38(33):5703-5713. R831709 (2005)
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Journal Article Children's inhalation exposure to methamidophos from sprayed potato fields in Washington State: exploring the use of probabilistic modeling of meteorological data in exposure assessment. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY Ramaprasad J, Tsai MG, Fenske RA, Faustman EM, Griffith WC, Felsot AS, Elgethun K, Weppner S, Yost MG Ramaprasad J, Tsai MG, Fenske RA, Faustman EM, Griffith WC, Felsot AS, Elgethun K, Weppner S, Yost MG. Children's inhalation exposure to methamidophos from sprayed potato fields in Washington State:exploring the use of probabilistic modeling of meteorological data in exposure assessment. Journal of Exposure Science and Environmental Epidemiology 2009;19(6):613-623. R831709 (2007)
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Journal Article Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. None Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE Richter RJ, Jampsa RL, Jarvik GP, Costa LG, Furlong CE. Determination of paraoxonase 1 status and genotypes at specific polymorphic sites. Current Protocols in Toxicology 2004;19(1):4. R831709 (2007)
Journal Article Determination of paraoxonase (PON1) status without the use of toxic organophosphate substrates. CIRCULATION:CARDIOVASCULAR GENETICS Richter RJ, Jarvik GP, Furlong CE Richter RJ, Jarvik GP, Furlong CE. Determination of paraoxonase (PON1) status without the use of toxic organophosphate substrates. Circulation: Cardiovascular Genetics 2008;1(2):147-152. R831709 (2007)
Journal Article Paraoxonase 1 (PON1) status and substrate hydrolysis. TOXICOLOGY AND APPLIED PHARMACOLOGY Richter RJ, Jarvik GP, Furlong CE Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 (PON1) status and substrate hydrolysis. Toxicology and Applied Pharmacology 2009;235(1):1-9. R831709 (2007)
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R834514 (2013)
R834514 (Final)
Journal Article Paraoxonase 1 (PON1) status as a risk factor for disease or exposure. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Richter RJ, Jarvik GP, Furlong CE Richter RJ, Jarvik GP, Furlong CE. Paraoxonase 1 (PON1) status as a risk factor for disease or exposure. Advances in Experimental Medicine and Biology 2010;660:29-35. R831709 (2007)
Journal Article Cadmium-induced differential toxicogenomic response in resistant and sensitive mouse strains undergoing neurulation. TOXICOLOGICAL SCIENCE Robinson JF, Yu X, Hong S, Griffith WC, Beyer R, Kim E, Faustman EM Robinson JF, Yu X, Hong S, Griffith WC, Beyer R, Kim E, Faustman EM. Cadmium-induced differential toxicogenomic response in resistant and sensitive mouse strains undergoing neurulation. Toxicological Sciences 2009;107(1):206-219. R831709 (2007)
R832733 (Final)
Journal Article Embryonic toxicokinetic and dynamic differences underlying strain sensitivity to cadmium during neurulation. REPRODUCTIVE TOXICOLOGY Robinson JF, Yu X, Hong S, Zhou C, Kim N, DeMasi D, Faustman EM Robinson JF, Yu X, Hong S, Zhou C, Kim N, DeMasi D, Faustman EM. Embryonic toxicokinetic and dynamic differences underlying strain sensitivity to cadmium during neurulation. Reproductive Toxicology 2010;29(3):279-285. R831709 (2007)
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R834514 (2011)
R834514 (2012)
R834514 (2013)
Journal Article Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. TOXICOLOGICAL SCIENCES Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM Sidhu JS, Ponce RA, Vredevoogd MA, Yu X, Gribble E, Hong S-W, Schneider E, Faustman EM. Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells. Toxicological Sciences 2006;89(2):475-484. R831709 (2005)
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Journal Article Anthropological and psychological merge: design of a stress measure for Mexican farmworkers. CULTURE, MEDICINE AND PSYCHIATRY Snipes SA, Thompson B, O’Connor K, Godina R, Ibarra G Snipes SA, Thompson B, O’Connor K, Godina R, Ibarra G. Anthropological and psychological merge:design of a stress measure for Mexican farmworkers. Culture Medicine and Psychiatry 2007;31(3):359-388. R831709 (2005)
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Journal Article Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. HARMFUL ALGAE Stevens RC, Soelberg SD, Eberhart BT, Spencer S, Wekell JC, Chinowsky TM, Trainer VL, Furlong CE Stevens RC, Soelberg SD, Eberhart BT, Spencer S, Wekell JC, Chinowsky TM, Trainer VL, Furlong CE. Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. Harmful Algae 2007;6(2):166-174. R831709 (2005)
R831709 (2007)
Journal Article Engineered recombinant human paraoxonase 1 (rHUPON1) purified from Escherichia coli protects against organophosphate poisoning. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA Stevens RC, Suzuki SM, Cole TB, Park SS, Richter RJ, Furlong CE Stevens RC, Suzuki SM, Cole TB, Park SS, Richter RJ, Furlong CE. Engineered recombinant human paraoxonase 1 (rHUPON1) purified from Escherichia coli protects against organophosphate poisoning. Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12780-12784. R831709 (2007)
Journal Article Health symptoms and exposure to organophosphate pesticides in farmworkers. AMERICAN JOURNAL OF INDUSTRIAL MEDICINE Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I Strong LL, Thompson B, Coronado GD, Griffith WC, Vigoren EM, Islas I. Health symptoms and exposure to organophosphate pesticides in farmworkers. American Journal of Industrial Medicine 2004;46(6):599-606. R831709 (2005)
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Journal Article Factors associated with pesticide safety practices in farmworkers. None Strong LL, Thompson B, Koepsell TD, Meischke H Strong LL, Thompson B, Koepsell TD, Meischke H. Factors associated with pesticide safety practices in farmworkers. American Journal of Industrial Medicine 2008;51(1):69-81. R831709 (2005)
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R832740 (Final)
Journal Article Reducing the take-home pathway of pesticide exposure: behavioral outcomes from the Para Niños Saludables study. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Strong LL, Thompson B, Koepsell TD, Meischke H, Coronado GD Strong LL, Thompson B, Koepsell TD, Meischke H, Coronado GD. Reducing the take-home pathway of pesticide exposure:behavioral outcomes from the Para Niños Saludables study. Journal of Occupational and Environmental Medicine 2009;51(8):922-933. R831709 (2007)
R834514 (Final)
R834514C001 (Final)
Journal Article Engineering human PON1 in an E. coli expression system. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Suzuki SM, Stevens RC, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE Suzuki SM, Stevens RC, Richter RJ, Cole TB, Park S, Otto TC, Cerasoli DM, Lenz DE, Furlong CE. Engineering human PON1 in an E. coli expression system. Advances in Experimental Medicine and Biology 2010;660:37-45. R831709 (2007)
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Journal Article Pesticide take-home pathway among children of agricultural workers: study design, methods, and baseline findings. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Thompson B, Coronado GD, Grossman JE, Puschel K, Solomon CC, Islas I, Curl CL, Shirai JH, Kissel JC, Fenske RA Thompson B, Coronado GD, Grossman JE, Puschel K, Solomon CC, Islas I, Curl CL, Shirai JH, Kissel JC, Fenske RA. Pesticide take-home pathway among children of agricultural workers: study design, methods, and baseline findings. Journal of Occupational and Environmental Medicine 2003;45(1):42-53. R826886 (2000)
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Journal Article Para niños saludables: a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers None Thompson B, Coronado GD, Vigoren EM, Griffith WC, Fenske RA, Kissel JC, Shirai JH, Faustman EM Thompson B, Coronado GD, Vigoren EM, Griffith WC, Fenske RA, Kissel JC, Shirai JH, Faustman EM. Para niños saludables:a community intervention trial to reduce organophosphate pesticide exposure in children of farmworkers.Environmental Health Perspectives 2008;116(5):687-694. R831709 (2005)
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Journal Article Genetic polymorphisms and mechanisms of neurotoxicity: overview. NEUROTOXICOLOGY Tiffany-Castiglioni E, Venkratraj V, Qian Y Tiffany-Castiglioni E, Venkratraj V, Qian Y. Genetic polymorphisms and mechanisms of neurotoxicity:overview. Neurotoxicology 2005;26(4):641-649. R831709 (2007)
R831709C002 (2004)
Journal Article The Washington aerial spray drift study: modeling pesticide spray drift deposition from an aerial application. ATMOSPHERIC ENVIRONMENT Tsai M-Y, Elgethun K, Ramaprasad J, Yost MG, Felsot AS, Hebert VR, Fenske RA Tsai M-Y, Elgethun K, Ramaprasad J, Yost MG, Felsot AS, Hebert VR, Fenske RA. The Washington aerial spray drift study: modeling pesticide spray drift deposition from an aerial application. Atmospheric Environment 2005;39(33):6194-6203. R831709 (2005)
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R831709C004 (2006)
Journal Article The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS VanDeMark KL, Guizzetti M, Giordano G, Costa LG VanDeMark KL, Guizzetti M, Giordano G, Costa LG. The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons. Journal of Pharmacology and Experimental Therapeutics 2009;329(2):532-542. R831709 (2007)
Journal Article Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. ALCOHOLISM:EXPERIMENTAL AND CLINICAL RESEARCH VanDeMark KL, Guizzetti M, Giordano G, Costa LG VanDeMark KL, Guizzetti M, Giordano G, Costa LG. Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. Alcoholism, Clinical and Experimental Research 2009; 33(11):1945-1955. R831709 (2007)
Journal Article The Washington aerial spray drift study: children's exposure to methamidophos in an agricultural community following fixed-wing aircraft applications. None Weppner S, Elgethun K, Lu C, Herbert V, Yost MG, Fenske RA Weppner S, Elgethun K, Lu C, Herbert V, Yost MG, Fenske RA. The Washington aerial spray drift study:children's exposure to methamidophos in an agricultural community following fixed-wing aircraft applications. Journal of Exposure Science and Environmental Epidemiology 2006;16(5):387-396. R831709 (2005)
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Journal Article Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS NEUROLOGY Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown Jr. RH Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, Furlong CE, Brown Jr. RH. Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS. Neurology 2008;70(12):929-934. R831709 (2007)
Journal Article Comparative risk and policy analysis in environmental health. RISK ANALYSIS Wong EY, Ponce RA, Farrow S, Bartell SM, Lee RC, Faustman EM Wong EY, Ponce RA, Farrow S, Bartell SM, Lee RC, Faustman EM. Comparative risk and policy analysis in environmental health. Risk Analysis 2003;23(6):1337-1349. R831709 (2005)
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Journal Article Assessing the health benefits of air pollution reduction for children. ENVIRONMENTAL HEALTH PERSPECTIVES Wong EY, Gohlke J, Griffith WC, Farrow S, Faustman EM Wong EY, Gohlke J, Griffith WC, Farrow S, Faustman EM. Assessing the health benefits of air pollution reduction for children. Environmental Health Perspectives 2004;112(2):226-232. R831709 (2005)
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Journal Article Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. NEUROTOXICOLOGY Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, Holland NT. Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates. NeuroToxicology 2005;26(2):199-209. R831709 (2005)
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R831710 (2004)
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R831710 (Final)
Journal Article Essential role of extracellular matrix (ECM) overlay in establishing the functional integrity of primary neonatal rat Sertoli cell/gonocyte co-cultures: an improved in vitro model for assessment of male reproductive toxicity. TOXICOLOGY SCIENCE Yu X, Sidhu JS, Hong S, Faustman EM Yu X, Sidhu JS, Hong S, Faustman EM. Essential role of extracellular matrix (ECM) overlay in establishing the functional integrity of primary neonatal rat Sertoli cell/gonocyte co-cultures:an improved in vitro model for assessment of male reproductive toxicity. Toxicological Sciences 2005;84(2):378-393. R831709 (2005)
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Journal Article A system-based approach to interpret dose- and time-dependent microarray data: quantitative integration of gene ontology analysis for risk assessment. TOXICOLOGICAL SCIENCES Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM Yu X, Griffith WC, Hanspers K, Dillman III JF, Ong H, Vredevoogd MA, Faustman EM. A system-based approach to interpret dose-and time-dependent microarray data:quantitative integration of gene ontology analysis for risk assessment. Toxicological Sciences 2006;92(2):560-577. R831709 (2005)
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R832733 (Final)
Journal Article Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures. TOXICOLOGICAL SCIENCES Yu X, Hong S, Faustman EM Yu X, Hong S, Faustman EM. Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures. Toxicological Sciences 2008;104(2):385-396. R831709 (2007)
R832733 (Final)
Journal Article Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways. TOXICOLOGY AND APPLIED PHARMACOLOGY Yu X, Robinson JF, Gribble E, Hong SW, Sidhu JS, Faustman EM Yu X, Robinson JF, Gribble E, Hong SW, Sidhu JS, Faustman EM. Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways. Toxicology and Applied Pharmacology 2008;233(3):389-403. R831709 (2007)
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Journal Article Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates. TOXICOLOGY AND APPLIED PHARMACOLOGY Yu X, Hong S, Moreira EG, Faustman EM Yu X, Hong S, Moreira EG, Faustman EM. Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity:lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates. Toxicology and Applied Pharmacology 2009;239(3):325-336. R831709 (2007)
R832733 (Final)
Journal Article A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and ethylmercury in mouse embryonic fibroblast. TOXICOLOGICAL SCIENCES Yu X, Robinson JF, Sidhu JS, Hong S, Faustman EM Yu X, Robinson JF, Sidhu JS, Hong S, Faustman EM. A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and ethylmercury in mouse embryonic fibroblast. Toxicological Sciences 2010;114(2):356-377. R831709 (2007)
R832733 (Final)
R834514 (2011)
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R834514 (2013)
R834514 (Final)
R834514C003 (Final)
Presentation Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. None Cole TC, Pettan-Brewer C Cole TC, Pettan-Brewer C. Modulation of low-level organophosphate toxicity by human PON1, as assessed by microarray analysis. Presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 5-9, 2006. R831709 (2005)
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Presentation Reducing the take-home pathway of pesticide exposure. None Coronado GD Coronado GD. Reducing the take-home pathway of pesticide exposure. Presented at the Fred Hutchinson Cancer Research Center, Seattle, WA, 2005. R831709C003 (2005)
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Presentation Reducing the take-home pathway of pesticide exposure. None Coronado GD Coronado GD. Reducing the take-home pathway of pesticide exposure. Presented at the University of Washington, Seattle, WA, 2005. R831709C003 (2005)
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Presentation Reducing the take-home pathway of pesticide exposure. None Coronado GD Coronado GD. Reducing the take-home pathway of pesticide exposure. Presented to the summer undergraduate interns, Fred Hutchinson Cancer Research Center, 2005. R831709C003 (2006)
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Presentation Post-application methamidophos residues on indoor and outdoor surfaces and children’s hands. None Faustman EM Faustman EM. Post-application methamidophos residues on indoor and outdoor surfaces and children’s hands. Presented at the Fifth International Symposium—The Future of Rural Peoples: Rural Economy, Healthy People, Environment, Rural Communities, Saskatoon, Saskatchewan, Canada, October 19-23, 2003 (abstract #307). R831709C004 (2004)
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Presentation Integration of toxicogenomic and knowledge-based pathway mapping for elucidating shared molecular mechanisms of metal toxicity. None Faustman EM, Yu X, Sidhu JS, Hong S, et al Faustman EM, Yu X, Sidhu JS, Hong S, et al. Integration of toxicogenomic and knowledge-based pathway mapping for elucidating shared molecular mechanisms of metal toxicity. Poster presented at the 10th International Congress of Toxicology, Tampere, Finland, July 11-15, 2004. R831709C001 (2005)
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Presentation Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. None Faustman EM, Yu X, Sidhu J, Robinson J Faustman EM, Yu X, Sidhu J, Robinson J. Toxicant affects on ubiquitin-proteosome systems: lessons from cross-compound and cross-system assessments. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. R831709C001 (2005)
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Presentation Computational model for dose-response comparisons of two mechanistic hypotheses for ethanol-induced neurodevelopmental toxicity. None Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational model for dose-response comparisons of two mechanistic hypotheses for ethanol-induced neurodevelopmental toxicity. Presented at the Society for Risk Analysis 2004 Annual Meeting, Palm Springs, CA, December 5-8, 2004. R831709C001 (2005)
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Presentation Computational models for the acquisition of neocortical neurons in the developing humans, monkey, and mouse: cross species comparison of toxicodynamics. None Gohlke JM, Griffith WC, Faustman EM Gohlke JM, Griffith WC, Faustman EM. Computational models for the acquisition of neocortical neurons in the developing humans, monkey, and mouse: cross species comparison of toxicodynamics. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. R831709C001 (2005)
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Presentation Systems biology evaluation of toxicogenomic microarray data using go-quant to analyze how toxicants alter gene pathways and functional gene categories. None Griffith WC, Yu X, Hanspers K, Dillman III JF, Ong H, Vredevoogd M, Faustman EM Griffith WC, Yu X, Hanspers K, Dillman III JF, Ong H, Vredevoogd M, Faustman EM. Systems biology evaluation of toxicogenomic microarray data using go-quant to analyze how toxicants alter gene pathways and functional gene categories. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 3-6, 2006. R831709 (2005)
R832733 (Final)
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Presentation Evaluation of exposure of young children of orchard workers to organophosphate pesticides. None Griffith WC Griffith WC. Evaluation of exposure of young children of orchard workers to organophosphate pesticides. Presented at the International Conference on Environmental Epidemiology and Exposure, Paris, France, September 2-6, 2006. R831709 (2005)
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Presentation Organophosphate pesticide gene-environment interactions: lessons learned and future challenges. None Griffith W, Ramaprasad J, Coronado GC, Thompson B, Vigoren EM, Faustman EM Griffith W. Organophosphate pesticide gene-environment interactions: lessons learned and future challenges. Presented at the 40th Annual Meeting of the Environmental Mutagen Society, St. Louis, MO, October 26, 2009. R831709 (2007)
Presentation Increased pesticide exposure among agricultural communities in Washington caused by volatilization from sprayed fields. None Ramaprasad J, Tsai T, Elgethun K, Herbert V, et al Ramaprasad J, Tsai T, Elgethun K, Herbert V, et al. Increased pesticide exposure among agricultural communities in Washington caused by volatilization from sprayed fields. Presented at the Society for Risk Analysis 2004 Annual Meeting, Palm Springs, CA, December 5-8, 2004. R831709C004 (2005)
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Presentation Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. None Robinson J, Yu X, Sidhu J, Hong S, Kim E, Faustman EM Robinson J, Yu X, Sidhu J, Hong S, Kim E, Faustman EM. Examination of metal-induced cell cycle alterations and apoptosis in C57BL/6 and SWV mouse embryonic fibroblasts. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. R831709C001 (2005)
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Presentation Reducing the take-home pathway of pesticide exposure. None Thompson B Thompson B. Reducing the take-home pathway of pesticide exposure. Presented at the Quarterly Fellows: Seminar for Biobehavioral Cancer Training, University of Washington, Seattle, WA, 2004. R831709C003 (2005)
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Presentation Pesticide spray drift monitoring of orchard airblast application:New approaches. None Tsai M, Yost MG, Felsot AS, Galvin K, Fenske RA, Larson TV Tsai M, Yost MG, Felsot AS, Galvin K, Fenske RA, Larson TV. Pesticide spray drift monitoring of orchard airblast application: New approaches. Presented at the Joint ISEE/ISEA Conference on Environmental Epidemiology and Exposure (18th ISEE Conference and 16th ISEA Conference), Paris, France, September 2-6, 2006. R831709C004 (2007)
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Presentation Methods for assessing the effect of a randomized community educational intervention on the take-home pathway of organophosphate pesticide exposure. None Vigoren E, Griffith W Vigoren E, Griffith W. Methods for assessing the effect of a randomized community educational intervention on the take-home pathway of organophosphate pesticide exposure. Presented at the Society for Risk Analysis Annual Meeting, Baltimore, MD, December 3-6, 2006. R831709 (2005)
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Presentation Challenges in Incorporating Genomic Information into Risk Assessment: Development of a Systems Biology Framework. None Vredevoogd M, Yu X Vredevoogd M, Yu X. Challenges in Incorporating Genomic Information into Risk Assessment:Development of a Systems Biology Framework. Presented at the Society for Risk Analysis Annual Meeting, Palm Springs, CA. December 5-8, 2004. R831709 (2005)
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Presentation Health & Safety in Western Agriculture Conference:Research to Practice. None Yost M, Tsai MY, Fenske R. Air Blast Applications:Pesticide drift deposition modeling Yost M, Tsai MY, Fenske R. Air Blast Applications: Pesticide drift deposition modeling. Presented at at the Health & Safety in Western Agriculture Conference: Research to Practice. Agrochemical/Respiratory Protection Session-R2P, Pacific Grove, CA, September 20-22, 2006. R831709C004 (2007)
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Presentation Integrative analysis of genome-wide gene expression and pathway mapping in mouse embryonic fibroblast (MEF) exposed to cadmium, arsenic, and methylmercury: induction of oxidative stress, disruption of ubiquitin-proteasome system and cell cycle regulation. None Yu X, Sidhu J, Robinson J, Hong S, Faustman EM Yu X, Sidhu J, Robinson J, Hong S, Faustman EM. Integrative analysis of genome-wide gene expression and pathway mapping in mouse embryonic fibroblast (MEF) exposed to cadmium, arsenic, and methylmercury: induction of oxidative stress, disruption of ubiquitin-proteasome system and cell cycle regulation. Presented at the Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. R831709C001 (2005)
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Proceedings PON1 and organophosphate toxicity. None Costa L. Costa L. PON1 and organophosphate toxicity. In: Proccedings of the 2nd International Conference on Paraoxonases, Hajduszoboszio, Hungary, September 7-10, 2006. R831709C002 (2007)
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Proceedings The functional consequences of polymorphisms in the human PON1 gene. None Furlong C. Furlong C. The functional consequences of polymorphisms in the human PON1 gene. In: Proccedings of the 2nd International Conference on Paraoxonases, Hajduszoboszio, Hungary, September 7-10, 2006. R831709C002 (2007)
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