Grantee Research Project Results
Journal Publications Details for Grant Number R835550
Identification and Scientific Validation of AOPS Involving Genomic and Nongenomic Intracellular Thyroid Hormone Signaling in Neurodevelopment
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page without
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
---|---|---|---|---|---|---|
Journal Article | From the cover: BDE-47 and BDE-49 inhibit axonal growth in primary rat hippocampal neuron-glia co-cultures via ryanodine receptor-dependent mechanisms. | TOXICOLOGICAL SCIENCES | Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ | Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ. From the cover:BDE-47 and BDE-49 inhibit axonal growth in primary rat hippocampal neuron-glia co-cultures via ryanodine receptor-dependent mechanisms. Toxicological Sciences 2017;156(2):375-386. |
R835550 (Final) |
|
Journal Article | BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action. | SCIENTIFIC REPORTS | Dach K, Bendt F, Huebenthal U, Giersiefer S, Lein PJ, Heuer H, Fritschea E | Dach K, Bendt F, Huebenthal U, Giersiefer S, Lein PJ, Heuer H, Fritschea E. BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action. Scientific Reports 2017;7:44861 (11 pp.). |
R835550 (Final) |
|
Journal Article | Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). | None | Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ | Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ. Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). Aquatic Toxicology 2018;200:50-61. |
R835550 (Final) R835799 (2017) |
|
Journal Article | Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. | MOLECULAR BRAIN | Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ | Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ. Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. Molecular Brain 2015;8:10 (15 pp.). |
R835432 (2014) R835550 (Final) |
|
Journal Article | TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs | ALTEX | Klose J, TRigges J, Masjosthusmann S, Schmuck K, Bendt F, Hubenthal U, Petzsch P, Kohrer K, Koch K, Fritsche E | Klose J, TRigges J, Masjosthusmann S, Schmuck K, Bendt F, Hubenthal U, Petzsch P, Kohrer K, Koch K, Fritsche E. TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs. Altex 2021;38(2):215-234. |
R835550 (Final) |
|
Journal Article | Chasing the elusive benzofuran impurity of the THR antagonist NH-3: synthesis, isotope labeling, and biological activity. | JOURNAL OF ORGANIC CHEMISTRY | Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V | Singh L, Pressly B, Mengeling BJ, Fettinger JC, Furlow JD, Lein PJ, Wulff H, Singh V. Chasing the elusive benzofuran impurity of the THR antagonist NH-3: synthesis, isotope labeling, and biological activity. Journal of Organic Chemistry 2016;81(5):1870-1876. |
R835164 (Final) R835550 (Final) |
|
Journal Article | Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95. | None | Frank DF, Miller GW, Connon RE, Geist J, Lein PJ | Frank DF, Miller GW, Connon RE, Geist J, Lein PJ. Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95. PeerJ 2017;5:e4106. doi:10.7717/peerj.4106. |
R835550 (Final) |
|
Journal Article | A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. | None | Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD | Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. Aquatic Toxicology 2017;190:1-10. |
R835550 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.