Grantee Research Project Results
Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in Children
EPA Grant Number: U915173Title: Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in Children
Investigators: Barber, Kimberly R.
Institution: Michigan State University
EPA Project Officer: Packard, Benjamin H
Project Period: January 1, 1997 through January 1, 2000
Project Amount: $68,000
RFA: STAR Graduate Fellowships (1997) RFA Text | Recipients Lists
Research Category: Fellowship - Epidemiology , Academic Fellowships , Human Health
Objective:
The objectives of this research project are
to: (1) examine the association between particulate matter (PM) with an aerodiameter
of 2.5
µm (PM2.5) and the incidence of asthmatic events in children; and (2) explore
dose-response relationships between ambient air quality levels in a Midwestern
community and severity of asthma symptoms.
Approach:
A multicenter prevalence study is proposed in three to five major metropolitan locations of the tricounty Michigan area (Genesee, Wayne, and Saginaw). Air pollution data will be extracted from the U.S. Environmental Protection Agency's (EPA) air monitoring stations in or near these areas. The PM2.5 level will be collected and averaged over 24-hour periods. Ozone, SO2, and CO are among the pollutant data to be extracted. Daily counts of admission to a hospital for asthma-related illness will be determined over the same 1-year period. Discharge diagnosis for ICD-9th revision code of 943.90 and 943.91 will be used. The plan of analysis will be modeled on a multivariate regression estimating the relative risk of an asthmatic admission for individuals on days with higher pollution levels compared with days of lower pollution levels.
Supplemental Keywords:
fellowship, particulate matter, PM, PM2.5, asthmatic events, asthma, air, ambient air, air quality, Midwest, ozone, sulfur dioxide, SO2, carbon monoxide, CO, air pollution, epidemiology, children, Michigan, MI., RFA, Health, Scientific Discipline, Air, PHYSICAL ASPECTS, ENVIRONMENTAL MANAGEMENT, HUMAN HEALTH, Susceptibility/Sensitive Population/Genetic Susceptibility, Physical Processes, Engineering, Risk Assessments, Air Pollution, Chemistry, particulate matter, Biology, genetic susceptability, Engineering, Chemistry, & Physics, Microbiology, Allergens/Asthma, Molecular Biology/Genetics, Air Pollution Effects, Children's Health, Health Effects, Disease & Cumulative Effects, air toxics, Risk Assessment, air quality, disease, sensitive populations, urban air pollution, urban air, cytokines, minority population, particulate emissions, environmental hazard exposures, allergen, asthma, immunology, particle size, stratospheric ozone, particle pollutants, epidemiology, fine particles, human airway epithelial calls, human exposure, respiratory, particulate exposure, children, exposure, particles, particulates, airway epithelial cells, air pollutants, airborne pollutants, urban air , toxics, environmentally caused disease, human health effects, human health risk, airway disease, environmental effects, exposure assessment, inhalation, ultrafine particlesProgress and Final Reports:
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.