Grantee Research Project Results
2002 Progress Report: Nanosensors for Detection of Aquatic Toxins
EPA Grant Number: R829599Title: Nanosensors for Detection of Aquatic Toxins
Investigators: Gawley, Robert E.
Institution: University of Miami
EPA Project Officer: Aja, Hayley
Project Period: March 1, 2002 through February 28, 2005
Project Period Covered by this Report: March 1, 2002 through February 28, 2003
Project Amount: $350,000
RFA: Exploratory Research: Nanotechnology (2001) RFA Text | Recipients Lists
Research Category: Nanotechnology , Water Quality , Safer Chemicals
Objective:
The objective of this research project is to: design and prepare nanoscale sensors for the detection of marine toxins: domoic acid, brevetoxin, ciguatoxin, cylindrospermopsin, and tetrodotoxin.
Progress Summary:
This interim report covers only 8 months of support, and is submitted to close the grant at the University of Miami so that it can be transferred to the University of Arkansas. By the time the grant proposal was funded, the principal investigator knew that he would be moving to the University of Arkansas, so an attempt was made to conserve as much of the U.S. Environmental Protection Agency funds for transfer as possible.
We have begun synthesis of three-generation dendrimers for use as hosts for the toxin analytes. We also have begun the synthesis of the chemical linker that we will use to attach the dendrimer and the combinatorially designed host to the solid phase synthesis bead.
Future Activities:
We will resume activities at the University of Arkansas in January 2003, and continue synthesis of the chemical linker that will be used to attach the dendrimer and the combinatorially designed host to the solid phase synthesis bead.
Journal Articles:
No journal articles submitted with this report: View all 3 publications for this projectSupplemental Keywords:
red tide, harmful algal bloom, HAB, chemosensor, fluorescence sensor, combinatorial chemistry, synthesis, nanotechnology, peptide mimics, orphan receptor, receptor mimics, domoic acid, brevetoxin, ciguatoxin, cylin drospermopsin, tetrodotoxin, three-generation dendrimers., RFA, Scientific Discipline, Water, Ecosystem Protection/Environmental Exposure & Risk, Sustainable Industry/Business, Sustainable Environment, Environmental Chemistry, Technology for Sustainable Environment, Analytical Chemistry, Monitoring/Modeling, algal blooms, New/Innovative technologies, Environmental Engineering, Engineering, Chemistry, & Physics, aquatic ecosystem, environmental monitoring, nanosensors, aqautic toxins, marine ecosystem, chemical sensors, marine biotoxins, nanotechnology, environmental sustainability, brevetoxins, chemical composition, aquatic toxins, environmentally applicable nanoparticles, pathogenic quantification, nanoscale sensors, sustainability, nano engineering, innovative technologies, biosensor, nanoengineeringRelevant Websites:
http://www.uark.edu/depts/cheminfo/uarkchem/facultystaff/faculty/gawley/index.html Exit
Progress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.