2012 Progress Report: Exploring New Questions of Multiple Air Pollutants, Sources and Health in Denver

EPA Grant Number: R834899
Title: Exploring New Questions of Multiple Air Pollutants, Sources and Health in Denver
Investigators: Peel, Jennifer , Hannigan, Michael P.
Institution: Colorado State University , University of Colorado at Boulder
EPA Project Officer: Ilacqua, Vito
Project Period: April 1, 2011 through March 31, 2013 (Extended to August 31, 2014)
Project Period Covered by this Report: April 1, 2012 through March 31,2013
Project Amount: $298,362
RFA: Exploring New Air Pollution Health Effects Links in Existing Datasets (2010) RFA Text |  Recipients Lists
Research Category: Air Quality and Air Toxics , Health Effects , Air

Objective:

This project is taking advantage of a rich and unique existing time-series to evaluate novel questions regarding the relationship between air pollution and hospital admissions in Denver, Colorado. We are leveraging 5 years of data from the Denver Aerosol Sources and Health (DASH) study, including daily fine particulate matter mass (PM­2.5; particulate matter less than 2.5 microns in diameter), species, and source factors, to examine the association of air pollution with novel health outcomes (Objective 1). Additionally, we will explore several questions aimed at providing insight regarding susceptible populations (Objective 2) as well as regarding other potential factors leading to heterogeneity of health effect estimates in relation to ambient air pollution (Objectives 3 and 4).

Progress Summary:

This summary represents progress during the second year of the research award (April 1, 2012 – March 31, 2013). Colorado State University IRB approval was renewed on August 10, 2012. We have continued to evaluate the air quality data used for this project, particularly the spatial patterns observed in the PM2.5 mass and species data in Denver. We have also examined the uncertainty of the fine PM data. Additionally, we have conducted an evaluation of the robustness of the source apportionment data to alternative ways of incorporating temperature.

Due to difficulty in finding qualified applicants, we obtained approval to hire a consultant in lieu of the biostatistics postdoctoral fellow position that was included in the budget. Dr. Zev Ross was hired in December 2012. We applied for a 1-year no-cost extension in January 2013; the extension was awarded in February 2013 (extension through March 2014). In March 2013, we participated in the advanced monitoring system and met with the EPA program officer to discuss the progress of the study. We obtained approval from EPA to add emergency department visits to the analysis. We are now in discussion with hospitals to determine the feasibility of adding data. We have finished Objective 1 of the project (with hospital admission data), and we have preliminary results for Objective 2. We also started planning for Objectives 3 and 4.

Future Activities:

The IRB approval for the project will be renewed in August 2013. We will continue to work on Objectives 2-4 of the project, which will be finished by October 2013. We will continue to work on obtaining emergency department visit data for the study period. Manuscripts will be developed and submitted.


Journal Articles on this Report : 4 Displayed | Download in RIS Format

Other project views: All 4 publications 4 publications in selected types All 4 journal articles
Type Citation Project Document Sources
Journal Article Xie M, Coons TL, Hemann JG, Dutton SJ, Milford JB, Peel JL, Miller SL, Kim S-Y, Vedal S, Sheppard L, Hannigan MP. Intra-urban spatial variability and uncertainty assessment of PM2.5 sources based on carbonaceous species. Atmospheric Environment 2012;60:305-315. R834899 (2012)
R834899 (2013)
R834899 (Final)
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Xie M, Coons TL, Dutton SJ, Milford JB, Miller SL, Peel JL, Vedal S, Hannigan MP. Intra-urban spatial variability of PM2.5-bound carbonaceous components. Atmospheric Environment 2012;60:486-494. R834899 (2012)
    R834899 (2013)
    R834899 (Final)
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Journal Article Xie M, Hannigan MP, Dutton SJ, Milford JB, Hemann JG, Miller SL, Schauer JJ, Peel JL, Vedal S. Positive matrix factorization of PM2.5:comparison and implications of using different speciation data sets. Environmental Science & Technology 2012;46(21):11962-11970. R834899 (2012)
    R834899 (2013)
    R834899 (Final)
  • Abstract from PubMed
  • Full-text: ES&T-Full Text HTML
    Exit
  • Abstract: ES&T-Abstract
    Exit
  • Other: ES&T-Full Text PDF
    Exit
  • Journal Article Xie M, Piedrahita R, Dutton SJ, Milford JB, Hemann JG, Peel JL, Miller SL, Kim S-Y, Vedal S, Sheppard L, Hannigan MP. Positive matrix factorization of a 32-month series of daily PM2.5 speciation data with incorporation of temperature stratification. Atmospheric Environment 2013;65:11-20. R834899 (2012)
    R834899 (2013)
    R834899 (Final)
  • Full-text: ScienceDirect-Full Text HTML
    Exit
  • Abstract: ScienceDirect-Abstract
    Exit
  • Other: ScienceDirect-Full Text PDF
    Exit
  • Supplemental Keywords:

    Particulate matter, cardiovascular disease, respiratory disease, autoimmune, immunosuppressive, metabolic syndrome

    Progress and Final Reports:

    Original Abstract
    2011 Progress Report
    2013 Progress Report
    Final Report