2015 Progress Report: Community-Based Participatory Research

EPA Grant Number: R834514C001
Subproject: this is subproject number 001 , established and managed by the Center Director under grant R834514
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: University of Washington Center for Child Environmental Health Risks Research (2010)
Center Director: Faustman, Elaine
Title: Community-Based Participatory Research
Investigators: Faustman, Elaine , Thompson, Engelberta
Current Investigators: Faustman, Elaine
Institution: University of Washington
EPA Project Officer: Callan, Richard
Project Period: October 1, 2010 through September 24, 2016
Project Period Covered by this Report: August 25, 2014 through September 24,2015
RFA: Children's Environmental Health and Disease Prevention Research Centers (with NIEHS) (2009) RFA Text |  Recipients Lists
Research Category: Children's Health , Health

Objective:

Since 1998, researchers of the University of Washington Center for Child Environmental Health Risks Research (the Center) have been using a multi-disciplinary research approach working in the lab, in the field, and in the community to understand the mechanisms that define children’s susceptibility to pesticides, identify the implications of this susceptibility for development and learning, and partner with our communities to translate our findings into risk communication, risk management, and prevention strategies.

The specific objectives of the two field-based projects—the community-based participatory research (CBPR) project and the pesticide exposure pathways research project—are:

  1. To improve our understanding of critical pathways of potential pesticide exposure for children; and
  2. To apply culturally-appropriate interventions to reduce children’s exposure to pesticides.

There have not been any changes to the specific aims submitted in the 2009 competing application; specifically, the aims are to:

  • Characterize the seasonal variability of organophosphate (OP) exposure across our cohort by sampling at times of peak OP usage and by evaluating OP metabolite profiles across time during these seasons;
  • Assess the influence of gene environment interactions on OP exposure and response profiles; and
  • Calculate the contributions from gene, environment and season to within-person and between-person variability of the urinary OP metabolites in farmworkers to identify quantitatively difference between persons and across seasons.

Secondarily, we will coordinate our cohort and household sampling with agricultural practices and field air monitoring done by our colleagues in the Pesticide Exposure Pathways Research Project. This will measure parent and oxon concentration for three OPs.

Progress Summary:

In February 2011 our community health promoters began re-contacting farmworkers and nonfarm workers in our cohort (from Years 05 through 09 studies) to participate in this new study. A total of 132 farmworkers and 90 non-farm workers were re-contacted before we were able to reach our recruitment goal of 60 farmworker and 40 non-farmworker households. Data collection began on March 17, 2011.

Data collection for Season 1 (Pre-Thinning season) was completed in late May, 2011, Season 2 (Thinning season) data collection took place June-August, 2011, and the final season of data collection (Non-spray season) occurred in November and December of 2011. During Season 2, we asked female participants, between 18 and 49 years of age, who were participating in the parent study, if they would be interested in participating in an additional Stress and Cortisol Project. We successfully recruited 27 women. We also coordinated with the Pesticides Exposure Pathways Research group to complete indoor and outdoor air sampling.

In the spring of 2012, a random selection of 41 participants from the larger CBPR Project were re-contacted to participate in one-on-one interviews to learn more about why they chose to provide biological samples for research and their experience in doing so. We learned that Hispanics have a strong understanding of and desire to contribute to biomedical research. Most participants were eager to participate because of self-described duty to help others and used words like "proud," "satisfied" and "pleasure" when describing their ability to contribute to a cause like this.

In February 2013, we held two Community Forums (one in English with the Community Advisory Board members and one in Spanish open to the community). During the forums we provided examples of information from this project that would be available for dissemination at a later date. We then queried the audience on the presentation and understandability of the information. The information gathered during these meetings informed the dissemination tools that were used to return individual results to participants in June - July 2015. During this time all 100 families (60 farm worker and 40 non-farm worker families) were re-contacted and offered a one-on-one meeting with one of our community health promoters to learn about the DMTP levels detected in their urine during the study; as well more information on pesticides and reducing pesticide exposure at home and in the work place. We were successful in locating and returning results to 92 of the 100 participating adults; eight were lost to follow-up (moved out of the area). The 92 participants who received their results also completed a short survey which will assist us in better understanding the nature of their work environment and potential points of pesticide exposure. The majority of participants who met with a community health worker to discuss their results voiced great appreciation for the results and information provided to them.

Significance

Recruitment and retention efforts were extremely successful in both the parent study and the Stress and Cortisol Project. Of the 100 families in the parent study, we only lost one non-farm worker family in Season 2, due to military service; and two farm worker families in Season 3 because they relocated out of state. Participants are very interested in continuing participation as we saw with the evaluation interviews where 39 of the 41 participants we re-contacted agreed to an interview. The qualitative data gathered during these interviews will help direct future work in biospecimen education and biomedical research among rural, Hispanic populations. A manuscript on the findings has been published in the American Journal of Public Health. Participants were very interested and enthusiastic about receiving individual results and appreciated the one-on-one meeting with the health worker who explained the results and dissemination materials in great deal.

Future Activities:

Data analyses of survey data continues and we continue to meet with our colleagues at the University of Washington to review outcomes and discuss dissemination and manuscript ideas and drafts. Data analyses of dust and biological samples continue at the University of Washington. We will work closely with the Biomarkers and Exposure Assessment Facility Core and the Biostatistics, Modeling and Risk Characterization Facility Core as more information is available.


Journal Articles on this Report : 2 Displayed | Download in RIS Format

Other subproject views: All 24 publications 15 publications in selected types All 15 journal articles
Other center views: All 507 publications 224 publications in selected types All 175 journal articles
Type Citation Sub Project Document Sources
Journal Article Holme F, Thompson B, Holte S, Vigoren EM, Espinoza N, Ulrich A, Griffith W, Faustman EM. The role of diet in children's exposure to organophosphate pesticides. Environmental Research 2016;147:133-140. R834514 (Final)
R834514C001 (2015)
R834514C001 (Final)
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  • Journal Article Shepherd-Banigan M, Hohl SD, Vaughan C, Ibarra G, Carosso E, Thompson B. "The promotora explained everything": participant experiences during a household-level diabetes education program. The Diabetes Educator 2014;40(4):507-515. R834514C001 (2015)
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  • Supplemental Keywords:

    RFA, Health, Scientific Discipline, INTERNATIONAL COOPERATION, ENVIRONMENTAL MANAGEMENT, Biochemistry, Children's Health, Environmental Policy, Biology, Risk Assessment, pesticide exposure, community-based intervention, age-related differences, pesticides, children's vulnerablity, biological markers, agricultural community

    Progress and Final Reports:

    Original Abstract
  • 2011 Progress Report
  • 2012
  • 2013 Progress Report
  • 2014
  • Final Report

  • Main Center Abstract and Reports:

    R834514    University of Washington Center for Child Environmental Health Risks Research (2010)

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R834514C001 Community-Based Participatory Research
    R834514C002 Pesticide Exposure Pathways
    R834514C003 Molecular Mechanisms
    R834514C004 Genetic Susceptibility