2001 Progress Report: The Role of Quinones, Aldehydes, Polycyclic Aromatic Hydrocarbons, and other Atmospheric Transformation Products on Chronic Health Effects in Children

EPA Grant Number: R827352C009
Subproject: this is subproject number 009 , established and managed by the Center Director under grant R827352
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Southern California Particle Center and Supersite
Center Director: Froines, John R.
Title: The Role of Quinones, Aldehydes, Polycyclic Aromatic Hydrocarbons, and other Atmospheric Transformation Products on Chronic Health Effects in Children
Investigators: Avol, Edward L. , Cho, Arthur K. , Froines, John R. , Miguel, Antonio
Institution: University of Southern California , University of California - Los Angeles
EPA Project Officer: Chung, Serena
Project Period: June 1, 1999 through May 31, 2005 (Extended to May 31, 2006)
Project Period Covered by this Report: June 1, 2000 through May 31, 2001
RFA: Airborne Particulate Matter (PM) Centers (1999) RFA Text |  Recipients Lists
Research Category: Air Quality and Air Toxics , Particulate Matter , Air


To assess inter-community variability of vehicular-related emissions across Southern California, and to potentially link the variability of specific reactive compounds in ambient air to observed patterns of respiratory health in Southern California children, Center investigators have embarked on an ambient polycyclic aromatic hydrocarbons (PAHs)/carbonyls/quinones sampling study. Field operations are being conducted in 12 Southern California communities to collect 24-hour samples, approximately once per week on differing days, to develop seasonal profiles of PAHs, aldehydes, and quinones for the 12 communities participating in the CHS. Center investigators expect that inter-community variability of specific organics, carbonyls, and quinones monitored in the study may help to disentangle previously observed correlated associations between gaseous entities, particle pollutants, and several respiratory health outcomes of California school children.

Progress Summary:

Samplers were deployed in Spring 2001 for actual data collection. Data available for the first sampling cycle (May-July 2001) suggest a regional transitional increase in quinones across the initial sampling sites, with a several-fold increase across communities in two of four quinones and virtually no change regionally in a third quinone (Figures 1a and 1b). Ambient napthalene concentrations varied from 86 to 650 nanograms per cubic meter, with Los Angeles basin (LAB) sites having higher observed levels. Other semivolatile PAHs varied in levels and order across the sites.

Figure 1a.

Figure 1a.

Figure 1b.

Figure 1b.

Figure Legend  
ATAS(AT) Atascadero (source site)
LM Lompoc (source site)
SC University of Southern California (source site)
BH Boyle Heights (source site) – freeway impacted
SD San Dimas (receptor site)
UP Upland (receptor site)
ML Mira Loma (receptor site)
RV Riverside (receptor site)

Source site – Site where little atmospheric chemistry is anticipated.
Receptor site – Site on eastern side of Los Angeles Basin where chemistry is expected.

Field operations continued at Lompoc, Upland, and Mira Loma from August through October 2001; those data are currently being analyzed. During November and December 2001, sampling was conducted at the initial three sampling sites (Atascadero, San Dimas, and Riverside). In January 2002, samplers were once again re-located to Lompoc, Upland, and Mira Loma and will remain there for the January/February 2002 sampling period.

Future Activities:

Alternating 2-month periods of sampling will continue between these two sets of three Southern California communities through May 2002. Sampling at the remaining six Children’s Health Study (CHS) sites is planned for mid-2002 through 2003. In this manner, we plan to develop seasonal information about inter-community PAH, carbonyls, and quinones in a cost-effective, logistically feasible, and scientifically credible protocol. The data will then be used in ongoing analyses of health outcomes for the CHS study and toxicological endpoints of interest in animal studies planned for several locations across LAB.

Journal Articles:

No journal articles submitted with this report: View all 5 publications for this subproject

Supplemental Keywords:

particulate matter, PM, quinones, polycyclic aromatic hydrocarbons, PAHs, aldehydes, ketones, metals, allergic airway disease, human exposure studies, asthma, cardiovascular effects, aerosol sampling, atmospheric aerosol, environmental monitoring, environmental statistics, California, CA, acute exposure, aerosols, air pollution, air quality, air toxics, airway disease, allergen, allergic response, ambient aerosol, assessment of exposure, asthma triggers, atmospheric chemistry, bioaerosols, biological response, childhood respiratory disease, children, dosimetry, environmental hazard exposures, environmental health hazard, environmental triggers, environmentally caused disease, epidemiology, exposure assessment, health effects, home, household, human exposure, human health effects, indoor air quality, inhaled particles, lead, outdoor air, particle concentrator, particle transport, particulate exposure, particulates, sensitive populations, toxicology, toxics, human health, air, geographic area, scientific discipline, health, RFA, physical aspects, susceptibility/sensitive population/genetic susceptibility, health effects, risk assessments, genetic susceptibility, health risk assessment, physical processes, biochemistry, particulate matter, environmental chemistry, environmental monitoring, state, aerosols, epidemiology, environmentally caused disease, environmental hazard exposures, allergen, indoor air quality, allergens, particle concentrator, air quality, children's health, human health risk, toxics, human health effects, particulates, sensitive populations, toxicology, environmental triggers, air pollution, airway disease, atmospheric chemistry, children, aldehydes, dosimetry, exposure, inhaled particles, PAH, asthma triggers, allergic airway disease, ambient aerosol, asthma, human exposure, particle transport, particulate exposure,, RFA, Health, Scientific Discipline, Air, Geographic Area, HUMAN HEALTH, particulate matter, Environmental Chemistry, Health Risk Assessment, Air Pollutants, State, Risk Assessments, mobile sources, Environmental Monitoring, Health Effects, ambient aerosol, asthma, engine exhaust, children's health, epidemiology, human health effects, motor vehicle emissions, quinones, particulate emissions, automotive emissions, air pollution, automobiles, automotive exhaust, children, PAH, human exposure, indoor air quality, California (CA), allergens, PM characteristics, aerosols, atmospheric chemistry

Relevant Websites:

http://www.scpcs.ucla.edu Exit

Progress and Final Reports:

Original Abstract
  • 1999
  • 2000
  • 2002 Progress Report
  • 2003 Progress Report
  • 2004 Progress Report
  • Final Report

  • Main Center Abstract and Reports:

    R827352    Southern California Particle Center and Supersite

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R827352C001 The Chemical Toxicology of Particulate Matter
    R827352C002 Pro-inflammatory and the Pro-oxidative Effects of Diesel Exhaust Particulate in Vivo and in Vitro
    R827352C003 Measurement of the “Effective” Surface Area of Ultrafine and Accumulation Mode PM (Pilot Project)
    R827352C004 Effect of Exposure to Freeways with Heavy Diesel Traffic and Gasoline Traffic on Asthma Mouse Model
    R827352C005 Effects of Exposure to Fine and Ultrafine Concentrated Ambient Particles near a Heavily Trafficked Freeway in Geriatric Rats (Pilot Project)
    R827352C006 Relationship Between Ultrafine Particle Size Distribution and Distance From Highways
    R827352C007 Exposure to Vehicular Pollutants and Respiratory Health
    R827352C008 Traffic Density and Human Reproductive Health
    R827352C009 The Role of Quinones, Aldehydes, Polycyclic Aromatic Hydrocarbons, and other Atmospheric Transformation Products on Chronic Health Effects in Children
    R827352C010 Novel Method for Measurement of Acrolein in Aerosols
    R827352C011 Off-Line Sampling of Exhaled Nitric Oxide in Respiratory Health Surveys
    R827352C012 Controlled Human Exposure Studies with Concentrated PM
    R827352C013 Particle Size Distributions of Polycyclic Aromatic Hydrocarbons in the LAB
    R827352C014 Physical and Chemical Characteristics of PM in the LAB (Source Receptor Study)
    R827352C015 Exposure Assessment and Airshed Modeling Applications in Support of SCPC and CHS Projects
    R827352C016 Particle Dosimetry
    R827352C017 Conduct Research and Monitoring That Contributes to a Better Understanding of the Measurement, Sources, Size Distribution, Chemical Composition, Physical State, Spatial and Temporal Variability, and Health Effects of Suspended PM in the Los Angeles Basin (LAB)