Mechanisms of Particulate-Induced Allergic AsthmaEPA Grant Number: R832139C003
Subproject: this is subproject number 003 , established and managed by the Center Director under grant R832139
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Johns Hopkins Center for Childhood Asthma in the Urban Environment
Center Director: Breysse, Patrick N.
Title: Mechanisms of Particulate-Induced Allergic Asthma
Investigators: Wills-Karp, Marsha
Institution: The Johns Hopkins University
EPA Project Officer: Callan, Richard
Project Period: November 1, 2003 through October 31, 2008 (Extended to October 31, 2010)
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003) RFA Text | Recipients Lists
Research Category: Children's Health , Health Effects , Health
The objectives of this research project are to: (1) establish a causal relationship between particulate matter (PM) exposure and asthma morbidity; and (2) determine the mechanisms by which PM elicits these effects.
Publications and Presentations:Publications have been submitted on this subproject: View all 18 publications for this subproject | View all 113 publications for this center
Journal Articles:Journal Articles have been submitted on this subproject: View all 18 journal articles for this subproject | View all 110 journal articles for this center
Supplemental Keywords:particulate matter, PM, airway hyperresponsiveness, AHR, asthma, complement factor 3, C3, children’s health, Baltimore,, RFA, Health, Scientific Discipline, Air, Geographic Area, HUMAN HEALTH, particulate matter, Health Risk Assessment, State, Allergens/Asthma, Health Effects, asthma, asthma triggers, children's health, air toxics, exposure, air pollution, children, airborne pollutants, human exposure, Maryland (MD), air pollutant, PM, allergens
Progress and Final Reports:2004 Progress Report
2005 Progress Report
2006 Progress Report
2007 Progress Report
Main Center Abstract and Reports:R832139 Johns Hopkins Center for Childhood Asthma in the Urban Environment
Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R832139C001 The Epidemiology of Susceptibility to Airborne Particulates and Allergens to Asthma in African Americans
R832139C002 A Randomized Controlled Trial of Behavior Changes in Home Exposure Control
R832139C003 Mechanisms of Particulate-Induced Allergic Asthma
R832139C004 Dendritic Cell Activation by Particulate Matter and Allergen