Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure PatternsEPA Grant Number: R831725C002
Subproject: this is subproject number 002 , established and managed by the Center Director under grant R831725
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
Center: Harvard Center for Children’s Environmental Health and Disease Prevention Research
Center Director: Hu, Howard
Title: Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure Patterns
Investigators: Shine, James P. , Spengler, John D.
Institution: Harvard T.H. Chan School of Public Health
EPA Project Officer: Callan, Richard
Project Period: June 1, 2004 through May 31, 2009 (Extended to May 31, 2011)
RFA: Centers for Children's Environmental Health and Disease Prevention Research (2003) RFA Text | Recipients Lists
Research Category: Children's Health , Health Effects , Health
The objectives of this research project are to: (1) assess the utility of size fractionation and sequential extraction studies for characterizing chat; (2) conduct a nested case-control study of the determinants of high versus low burdens of metals amongst children participating in Project 1 (R831725C001); and (3) produce standardized homogenized chat for Projects 3 and 4 (R831725C003 and R831725C004, respectively).
Publications and Presentations:Publications have been submitted on this subproject: View all 6 publications for this subproject | View all 35 publications for this center
Supplemental Keywords:children, Native American, tribal, mixtures, lead, PBPK, community, Superfund, intervention, environmental management,, RFA, Health, Scientific Discipline, INTERNATIONAL COOPERATION, ENVIRONMENTAL MANAGEMENT, Waste, Health Risk Assessment, Hazardous Waste, Children's Health, Hazardous, Risk Assessment, community-based intervention, epidemiology, fate and transport , developmental toxicity, Human Health Risk Assessment, neurodevelopmental toxicity, children's environmental health, biological markers, mining waste, metal wastes, metals, human health risk, metal contamination
Progress and Final Reports:2004 Progress Report
2005 Progress Report
2008 Progress Report
Main Center Abstract and Reports:R831725 Harvard Center for Children’s Environmental Health and Disease Prevention Research
Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R831725C001 Metals, Nutrition, and Stress in Child Development
R831725C002 Exposure Assessment of Children and Metals in Mining Waste: Composition, Environmental Transport, and Exposure Patterns
R831725C003 Manganese, Iron, Cadmium, and Lead Transport from the Environment to Critical Organs During Gestation and Early Development in a Rat Model
R831725C004 Metals Neurotoxicity Research Project