Biomarker Core

EPA Grant Number: R827355C010
Subproject: this is subproject number 010 , established and managed by the Center Director under grant R827355
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Airborne PM - Northwest Research Center for Particulate Air Pollution and Health
Center Director: Koenig, Jane Q.
Title: Biomarker Core
Investigators: Kalman, Dave , Dills, Russell , Katz, Bethany , Paulsen, Michael , Simpson, Chris
Current Investigators: Kalman, Dave , Dills, Russell , Simpson, Chris
Institution: University of Washington
EPA Project Officer: Chung, Serena
Project Period: June 1, 1999 through May 31, 2004 (Extended to May 31, 2006)
RFA: Airborne Particulate Matter (PM) Centers (1999) RFA Text |  Recipients Lists
Research Category: Air Quality and Air Toxics , Particulate Matter , Air

Objective:

The objective of this research project is to develop analytical methods for the determination of organic tracers of woodsmoke, and polycyclic aromatic hydrocarbon (PAH) contribution to particulate matter (PM) in urine and isoprostanes in urine and breath.

Publications and Presentations:

Publications have been submitted on this subproject: View all 19 publications for this subprojectView all 209 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 12 journal articles for this subprojectView all 109 journal articles for this center

Supplemental Keywords:

air pollution, air pollutants, particulate matter, PM, polycyclic aromatic hydrocarbons, PAHs, isoprostanes in urine, isoprostanes in breath, woodsmoke, organic tracers, methoxyphenols, levoglucosan, Seattle, Washington, WA, indoor exposure, outdoor exposure, biomarker, urinary methoxyphenol biomarker, high biomass smoke, dithiothreitol assay, oxidative potential of PM, ELISA, isoprostanes, health effects, fine particles., RFA, Health, Scientific Discipline, PHYSICAL ASPECTS, Air, ENVIRONMENTAL MANAGEMENT, Geographic Area, particulate matter, Toxicology, air toxics, Environmental Chemistry, Health Risk Assessment, Air Pollutants, State, Epidemiology, Air Pollution Effects, Northwest, Risk Assessments, Susceptibility/Sensitive Population/Genetic Susceptibility, Biochemistry, Physical Processes, genetic susceptability, Atmospheric Sciences, Risk Assessment, biostatistics, health effects, ambient aerosol, particulates, sensitive populations, ambient air quality, morbidity, cardiopulmonary responses, human health effects, exposure and effects, health risks, acute cardiovascular effects, hazardous air pollutants, exposure, epidemelogy, dose-response, air pollution, particle exposure, Human Health Risk Assessment, atmospheric aerosols, ambient particle health effects, mortality studies, cardiopulmonary response, inhalation, human exposure, human susceptibility, mortality, California (CA), biomarker based exposure inference, air quality, particle transport, cardiovascular disease, human health risk, aerosols, atmospheric chemistry, exposure assessment, environmental hazard exposures, toxics

Progress and Final Reports:

  • 1999
  • 2000
  • 2001
  • 2002 Progress Report
  • 2003 Progress Report
  • 2004
  • Final Report

  • Main Center Abstract and Reports:

    R827355    Airborne PM - Northwest Research Center for Particulate Air Pollution and Health

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R827355C001 Epidemiologic Study of Particulate Matter and Cardiopulmonary Mortality
    R827355C002 Health Effects
    R827355C003 Personal PM Exposure Assessment
    R827355C004 Characterization of Fine Particulate Matter
    R827355C005 Mechanisms of Toxicity of Particulate Matter Using Transgenic Mouse Strains
    R827355C006 Toxicology Project -- Controlled Exposure Facility
    R827355C007 Health Effects Research Core
    R827355C008 Exposure Core
    R827355C009 Statistics and Data Core
    R827355C010 Biomarker Core
    R827355C011 Oxidation Stress Makers