Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in Children

EPA Grant Number: U915173
Title: Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in Children
Investigators: Barber, Kimberly R.
Institution: Michigan State University
EPA Project Officer: Lee, Sonja
Project Period: January 1, 1997 through January 1, 2000
Project Amount: $68,000
RFA: STAR Graduate Fellowships (1997) RFA Text |  Recipients Lists
Research Category: Fellowship - Epidemiology , Academic Fellowships , Health Effects


The objectives of this research project are to: (1) examine the association between particulate matter (PM) with an aerodiameter of less than or equal to 2.5 µm (PM2.5) and the incidence of asthmatic events in children; and (2) explore dose-response relationships between ambient air quality levels in a Midwestern community and severity of asthma symptoms.


A multicenter prevalence study is proposed in three to five major metropolitan locations of the tricounty Michigan area (Genesee, Wayne, and Saginaw). Air pollution data will be extracted from the U.S. Environmental Protection Agency's (EPA) air monitoring stations in or near these areas. The PM2.5 level will be collected and averaged over 24-hour periods. Ozone, SO2, and CO are among the pollutant data to be extracted. Daily counts of admission to a hospital for asthma-related illness will be determined over the same 1-year period. Discharge diagnosis for ICD-9th revision code of 943.90 and 943.91 will be used. The plan of analysis will be modeled on a multivariate regression estimating the relative risk of an asthmatic admission for individuals on days with higher pollution levels compared with days of lower pollution levels.

Supplemental Keywords:

fellowship, particulate matter, PM, PM2.5, asthmatic events, asthma, air, ambient air, air quality, Midwest, ozone, sulfur dioxide, SO2, carbon monoxide, CO, air pollution, epidemiology, children, Michigan, MI., RFA, Health, Scientific Discipline, PHYSICAL ASPECTS, Air, ENVIRONMENTAL MANAGEMENT, HUMAN HEALTH, Air Pollution, particulate matter, air toxics, Chemistry, Air Pollution Effects, Risk Assessments, Microbiology, Susceptibility/Sensitive Population/Genetic Susceptibility, Allergens/Asthma, Disease & Cumulative Effects, Health Effects, Physical Processes, Children's Health, genetic susceptability, Molecular Biology/Genetics, Biology, Engineering, Engineering, Chemistry, & Physics, Risk Assessment, particle size, particulates, asthma, urban air, minority population, sensitive populations, fine particles, airway epithelial cells, human health effects, air pollutants, epidemiology, cytokines, exposure and effects, stratospheric ozone, human airway epithelial calls, particulate emissions, airway disease, exposure, particles, children, particle pollutants, particulate exposure, airborne pollutants, immunology, human exposure, inhalation, environmentally caused disease, urban air pollution, urban air , environmental effects, ultrafine particles, respiratory, air quality, allergen, environmental hazard exposures, toxics, disease, exposure assessment

Progress and Final Reports:

  • 1997
  • 1998
  • Final