Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in ChildrenEPA Grant Number: U915173
Title: Environmental Particulate Matter (PM2.5) and Risk of Asthmatic Events in Children
Investigators: Barber, Kimberly R.
Institution: Michigan State University
EPA Project Officer: Lee, Sonja
Project Period: January 1, 1997 through January 1, 2000
Project Amount: $68,000
RFA: STAR Graduate Fellowships (1997) RFA Text | Recipients Lists
Research Category: Fellowship - Epidemiology , Academic Fellowships , Health Effects
The objectives of this research project are to: (1) examine the association between particulate matter (PM) with an aerodiameter of 2.5 µm (PM2.5) and the incidence of asthmatic events in children; and (2) explore dose-response relationships between ambient air quality levels in a Midwestern community and severity of asthma symptoms.
A multicenter prevalence study is proposed in three to five major metropolitan locations of the tricounty Michigan area (Genesee, Wayne, and Saginaw). Air pollution data will be extracted from the U.S. Environmental Protection Agency's (EPA) air monitoring stations in or near these areas. The PM2.5 level will be collected and averaged over 24-hour periods. Ozone, SO2, and CO are among the pollutant data to be extracted. Daily counts of admission to a hospital for asthma-related illness will be determined over the same 1-year period. Discharge diagnosis for ICD-9th revision code of 943.90 and 943.91 will be used. The plan of analysis will be modeled on a multivariate regression estimating the relative risk of an asthmatic admission for individuals on days with higher pollution levels compared with days of lower pollution levels.