Testing the Metals Hypothesis in Spokane

EPA Grant Number: R824834C010
Subproject: this is subproject number 010 , established and managed by the Center Director under grant R824834
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Mickey Leland National Urban Air Toxics Research Center (NUATRC)
Center Director: Beskid, Craig
Title: Testing the Metals Hypothesis in Spokane
Investigators: Claiborn, Candis , Larsen, Timothy , Sheppard, Lianne (Elizabeth) A.
Institution: Washington State University , University of Washington
EPA Project Officer: Chung, Serena
Project Period: May 1, 1999 through December 31, 2000
RFA: Mickey Leland National Urban Air Toxics Research Center (NUATRC) (1997) RFA Text |  Recipients Lists
Research Category: Congressionally Mandated Center , Urban Air Toxics , Targeted Research

Objective:

The objectives of this research project are to: (1) determine associations between cardiovascular, respiratory outcomes, and particulate toxic and transition metals in Spokane; and (2) apportion particulate metals to relative sources.

Approach:

Investigators will construct a 7-year dataset based on 4 years of archived daily fine and course particulate samples and 3 years of samples that will be collected during the period of NUATRC support. This dataset will be used to evaluate the associations between ambient levels of particulate matter toxic metals, transition metals, and several health endpoints such as hospital admissions for respiratory or cardiovascular causes.

Expected Results:

This project will test the metals hypothesis by examining associations between health outcomes and particulate metals in a long-term epidemiological study. Results from this study will provide insight into the relative toxicity to the respiratory system of industrial, combustion, and soil-derived particulate matter, as well as the relative toxicity of specific particulate metal species.

Publications and Presentations:

Publications have been submitted on this subproject: View all 1 publications for this subprojectView all 144 publications for this center

Supplemental Keywords:

urban, air pollution, metals, PM2.5, particulate matter, asthma, respiratory disease, exposure., RFA, Health, Scientific Discipline, Air, Geographic Area, Air Pollution, particulate matter, air toxics, Health Risk Assessment, Epidemiology, State, Air Pollution Effects, Risk Assessments, Biochemistry, Environmental Monitoring, health effects, urban air quality, urban air, air pollutants, human health effects, hospital admissioms, Washington (WA), human exposure, lung inflamation, particulate exposure, urban air pollution, sensitive subgroups, Spokane, PM, human health, cardiotoxicity, metals, cardiovascular disease, airborne urban contaminants, biomarker

Progress and Final Reports:

  • 1999
  • Final Report

  • Main Center Abstract and Reports:

    R824834    Mickey Leland National Urban Air Toxics Research Center (NUATRC)

    Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
    R824834C001 Air Toxics Exposures Among Teenagers in New York City and Los Angeles - A Columbia-Harvard Study (TEACH)
    R824834C002 Cardiopulmonary Response to Particulate Exposure
    R824834C003 VOC Exposure in an Industry Impacted Community
    R824834C004 A Study of Personal Exposure to Air Toxics Among a Subset of the Residential U.S. Population (VOC Project)
    R824834C005 Methods Development Project for a Study of Personal Exposures to Toxic Air Pollutants
    R824834C006 Relationship Between Indoor, Outdoor and Personal Air (RIOPA)
    R824834C007 Development of the "Leland Legacy" Air Sampling Pump
    R824834C008 Source Apportionment of Indoor Polycyclic Aromatic Hydrocarbons (PAHs) in Urban Residences
    R824834C009 Development of a Personal Cascade Impactor Sampler (PCIS)
    R824834C010 Testing the Metals Hypothesis in Spokane
    R828678C001 Air Toxics Exposures Among Teenagers in New York City and Los Angeles—A Columbia-Harvard Study (TEACH)
    R828678C002 Cardiopulmonary Effects of Metal-Containing Particulate Exposure
    R828678C003 VOC Exposure in an Industry Impacted Community
    R828678C004 A Study of Personal Exposure to Air Toxics Among a Subset of the Residential U.S. Population (VOC Project)
    R828678C005 Oxygenated Urban Air Toxics and Asthma Variability in Middle School Children: A Panel Study (ATAC–Air Toxics and Asthma in Children)
    R828678C006 Relationship between Indoor, Outdoor and Personal Air (RIOPA). Part II: Analyses of Concentrations of Particulate Matter Species
    R828678C007 Development of the “Leland Legacy” Air Sampling Pump
    R828678C008 Source Apportionment of Indoor PAHs in Urban Residences 98-03B
    R828678C009 Development of a Personal Cascade Impactor Sampler (PCIS)
    R828678C010 Testing the Metals Hypothesis in Spokane
    R828678C011 A Pilot Geospatial Analysis of Exposure to Air Pollutants (with Special Attention to Air Toxics) and Hospital Admissions in Harris County, Texas
    R828678C012 Impact of Exposure to Urban Air Toxics on Asthma Utilization for the Pediatric Medicaid Population in Dearborn, Michigan
    R828678C013 Field Validation of the Sioutas Sampler and Leland Legacy Pump – Joint Project with EPA’s Environmental Technology Validation Program (ETV)
    R828678C014 Performance Evaluation of the 3M Charcoal Vapor Monitor for Monitor Low Ambient Concentrations of VOCs
    R828678C015 RIOPA Database Development
    R828678C016 Contributions of Outdoor PM Sources to Indoor and Personal Exposures: Analysis of PM Species Concentrations” Focused on the PM Speciation and Apportioning of Sources
    R828678C017 The Short and Long-Term Respiratory Effects of Exposure to PAHs from Traffic in a Cohort of Asthmatic Children