A Bioengineering Approach to Nanoparticle based Environmental RemediationEPA Grant Number: R829601
Title: A Bioengineering Approach to Nanoparticle based Environmental Remediation
Investigators: Strongin, Daniel R. , Douglas, Trevor , Schoonen, Martin A.A.
Institution: Temple University , Montana State University , The State University of New York at Stony Brook
EPA Project Officer: Savage, Nora
Project Period: February 1, 2002 through January 31, 2005
Project Amount: $399,979
RFA: Exploratory Research: Nanotechnology (2001) RFA Text | Recipients Lists
Research Category: Hazardous Waste/Remediation , Nanotechnology , Safer Chemicals
Description:The management of anthropogenic chemical toxins is a major environmental challenge. Various strategies have been employed to facilitate the degradation of this class of pollutant. Processes involving nano-sized materials have garnered interest because it is well known that nano-sized particles exhibit unusual thermal and photo-chemistry in a variety of chemical applications when compared to particles of larger dimensions. Our objective is to develop a bioengineering approach that can be used to develop nano-size catalytic materials as the basis for new remediation strategies. Here we propose a research program to assess the potential use of ferritin, and ferritin-derived compounds, as catalysts in environmental degradation processes. The ferritin system has the advantage of being environmentally benign and biodegradable. Ferritin is an iron-storage protein that consists of a native nano-size iron oxide core (ferrihydrite) encapsulated within a spherical protein cage (120 D diameter). Ferritin is commercially available, but it has also been cloned in our laboratory and can be produced in gram quantities. We have shown that the size of the iron oxide particles can be controlled to form homogeneous nanoparticles from 20 to 75 D. Also, the native iron oxide core of ferritin can be replaced by other metal oxides such as Mn and Co oxides. Such inorganic materials at more traditional size ranges (> micron) exhibit photocatalytic and catalytic activity in a variety of systems. Our hypothesis is that by assembling these materials as nanoparticles within the ferritin (i.e., the protein shell) we can "tune" their surface chemistry toward beneficial environmental chemistry through our control of their size and electronic structure. Furthermore, by the chemical functionalization of the ferritin cage, we can further alter the chemical reactivity of the nanoparticle. Our research focuses on: (1) the development of a bioengineered synthesis of a variety of homogeneous nano-sized metal and metal oxide particles; (2) the determination of the electronic properties of the nanoparticles and their reduced forms (i.e., the base metal) as a function of size; (3) a determination of the reactivity of the particles toward beneficial environmental chemistry, as a function of size and electronic structure.
Approach:The approach is to use our expertise in biomineralization to synthesize ferritin-like and ferritin-derived nano particles, concentrating initially on iron oxide and zero valent iron, but extending the research to other metal oxides and zero valent metals. The electronic structure and reactivity of these particles will be studied using a combination of modern surface science techniques as well as aqueous geochemical and photochemical techniques.
Expected Results:Our ultimate goal is to develop new nano-sized materials based on ferritin that may serve as catalysts in (photo)chemical degradation processes of common contaminants. We expect to gain significant insight into the dependence of electronic structure and reactivity on chemical composition of the nanoparticle.
Publications and Presentations:Publications have been submitted on this project: View all 26 publications for this project
Journal Articles:Journal Articles have been submitted on this project: View all 3 journal articles for this project
Supplemental Keywords:nanotechnology, environmental chemistry, remediation, soil, water, chemicals, toxics, organics, metals, solvents, photocatalysis., RFA, Scientific Discipline, Waste, Water, Sustainable Industry/Business, Physics, Remediation, Environmental Chemistry, Sustainable Environment, Technology for Sustainable Environment, Bioremediation, New/Innovative technologies, Engineering, Chemistry, & Physics, Environmental Engineering, nanoparticle remediation, decontamination, wastewater, bioengineering, nanoscale biopolymers, biodegradation, remediation technologies, nanotechnology, environmental sustainability, bio-engineering, nanocatalysts, biotechnology, groundwater remediation, aquifer remediation design, environmentally applicable nanoparticles, sustainability, groundwater contamination, biochemistry, cadmium, innovative technologies, contaminated aquifers, arsenic
Progress and Final Reports:2002 Progress Report