2015 Progress Report: Residential Exposure of Young Children to SVOCs

EPA Grant Number: R835642
Title: Residential Exposure of Young Children to SVOCs
Investigators: Stapleton, Heather , Ferguson, P. Lee , Webster, Thomas F.
Institution: Boston University
Current Institution: Duke University , Boston University
EPA Project Officer: Carleton, James N
Project Period: September 1, 2014 through August 31, 2017 (Extended to August 31, 2018)
Project Period Covered by this Report: July 1, 2014 through June 30,2015
Project Amount: $900,000
RFA: New Methods in 21st Century Exposure Science (2013) RFA Text |  Recipients Lists
Research Category: Safer Chemicals , Human Health , Health

Objective:

The goal of this research project is to investigate children’s exposure to semi-volatile organic compounds (SVOCs) in the home environment and identify links between sources of the SVOCs with exposure levels. 

Progress Summary:

To date, we have focused primarily on recruitment and collection of samples to support our study. Recruitment has gone well and we expect to complete recruitment in April 2016, at which time we will begin the chemical analyses of the samples. In addition to recruitment, we have spent some time exploring additional projects to support our interest in linking products with exposure levels. As such, we have piloted two studies over the past year. The first study has been investigating associations between the concentrations and loadings of flame retardants in residential sofas, with levels measured in indoor dust samples. This work is in progress, but we did present our preliminary data at the recent annual meeting of the Society of Environmental Toxicology & Chemistry (SETAC) in Salt Lake City, Utah in November 2015 (see Hammel et al. 2015). Furthermore, we piloted a second project investigating the utility of using silicone wristbands as personal biomonitors of exposure to organophosphate flame retardants (OPFRs). To accomplish this, we recruited a cohort of 40 adults and asked each participant to wear a pre-cleaned wristband for 5 days. During the 5 days, the participants also provided three urine samples. Analysis of the samples revealed that the mass of OPFRs measured on the silicone wristbands was significantly and positively correlated to the levels of the OPFR metabolites measured in pooled samples of urine. This work is currently in peer-review (see Hammel et al. 2016). These results suggest that silicone wristbands may be an ideal and improved personal biomonitor for measuring integrated exposure to SVOCs. 


Journal Articles on this Report : 1 Displayed | Download in RIS Format

Other project views: All 8 publications 4 publications in selected types All 4 journal articles
Type Citation Project Document Sources
Journal Article Hammel SC, Hoffman K, Webster TF, Anderson KA, Stapleton HM. Measuring personal exposure to organophosphate flame retardants using silicone wristbands and hand wipes. Environmental Science & Technology 2016;50(8):4483-4491. R835642 (2015)
R835642 (2016)
R835642 (2017)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: ACS-Abstract
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  • Supplemental Keywords:

    SVOCs, children’s exposure, dust, hand wipes, residential exposure, chemical exposure

    Progress and Final Reports:

    Original Abstract
  • 2016 Progress Report
  • 2017 Progress Report
  • Final