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Grantee Research Project Results

Selected Publications Details for Grant Number R828035

Infectivity and Virulence of Cryptosporidium Genotype H Oocysts in Healthy Adult Volunteers

RFA: Drinking Water (1999)

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Journal Article (10)
Reference Type Citation Progress Report Year Document Sources
Journal Article Alcantara CS, Yang C-H, Steiner TS, Barrett LJ, Lima AAM, Chappell CL, Okhuysen PC, White Jr AC, Guerrant RL. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. American Journal of Tropical Medicine and Hygiene 2003;68(3):325-328. R828035 (2001)
R829180 (2002)
  • Abstract from PubMed
  • Full-text: AJTMH Full Text
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  • Other: AJTMH PDF
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Journal Article Chappell C, Darkoh C, Schimmin L, Farhana N, Kim D, Okhuysen P, Hixson J. Fecal Indole as a Biomarker of Sceptibility to Cryptosporidium Infection. INFECTION AND IMMUNITY 2016;84(8):2299-2306. R824759 (Final)
R828035 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Full-text: ASM Journals - Full Text HTML
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  • Other: ASM Journals - Full Text PDF
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Journal Article Dann SM, Okhuysen PC, Salameh BM, Dupont HL, Chappell CL. Fecal antibodies to Cryptosporidium parvum in healthy volunteers. Infection and Immunity 2000;68(9):5068-5074. R828035 (2000)
  • Abstract from PubMed
  • Full-text: IAI Full Text
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  • Other: IAI PDF
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Journal Article Messner MJ, Chappell CL, Okhuysen PC. Risk assessment for Cryptosporidium: a hierarchical Bayesian analysis of human dose response data. Water Research 2001;35(16):3934-3940. R828035 (2001)
R829180 (2002)
  • Abstract from PubMed
  • Full-text: Science Direct Full Text
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  • Other: Science Direct PDF
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Journal Article Okhuysen PC, Chappell CL. Cryptosporidium virulence determinants – are we there yet? International Journal for Parasitology 2002;32(5):517-525. R828035 (2001)
R829180 (2002)
R829180 (Final)
  • Abstract from PubMed
Journal Article Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S. Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. Journal of Infectious Diseases 2002;185(9):1320-1325. R828035 (2001)
R829180 (2002)
  • Abstract from PubMed
  • Full-text: UChicago Full Text
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  • Other: UChicago PDF
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Journal Article Padda RS, Tsai A, Chappell CL, Okhuysen PC. Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. International Journal for Parasitology 2002;32(2):187-197. R828035 (2001)
R829180 (2002)
  • Abstract from PubMed
Journal Article Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White Jr AC. Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans. Infection and Immunity 2000;68(9):5405-5407. R828035 (2000)
  • Abstract from PubMed
  • Full-text: IAI Full Text
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  • Other: IAI PDF
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Journal Article Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Janecki A, White Jr AC. Expression of tumor necrosis factor alpha and interleukin 1beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. Infection and Immunity 2001;69(2):1172-1174. R828035 (2000)
  • Abstract from PubMed
  • Full-text: IAI Full Text
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  • Other: IAI PDF
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Journal Article Teunis PFM, Chappell CL, Okhuysen PC. Cryptosporidium dose-response studies: variation between hosts. Risk Analysis 2002;22(3):475-485. R828035 (2001)
R829180 (2002)
  • Abstract from PubMed

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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