TY - JOUR A1 - Agopian, A J A1 - Bhalla, A D A1 - Boerwinkle, E A1 - Finnell, R H A1 - Grove, M L A1 - Hixson, J E A1 - Shimmin, L C A1 - Sewda, A A1 - Stuart, C A1 - Zhong, Y A1 - Zhu, H A1 - Mitchell, L E T1 - Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Y1 - 2013/09/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 97 IS - 9 SP - 597 EP - 601 ER - TY - JOUR A1 - Cabrera, R M A1 - Finnell, R H A1 - Zhu, H A1 - Shaw, G M A1 - Wlodarczyk, B J T1 - Transcriptional analyses of two mouse models of spina bifida. Y1 - 2012/10/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 94 IS - 10 SP - 782 EP - 789 ER - TY - JOUR A1 - Denny, K J A1 - Coulthard, L G A1 - Jeanes, A A1 - Lisgo, S A1 - Simmons, D G A1 - Callaway, L K A1 - Wlodarczyk, B A1 - Finnell, R H A1 - Woodruff, T M A1 - Taylor, S M T1 - C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. Y1 - 2013/04/1 N1 - R835163 JF - JOURNAL OF IMMUNOLOGY J1 - J IMMUNOL J2 - J.Immunol. VL - 190 IS - 7 SP - 3493 EP - 3499 ER - TY - JOUR A1 - Denny, K J A1 - Coulthard, L G A1 - Finnell, R H A1 - Callaway, L K A1 - Taylor, S M A1 - Woodruff, T M T1 - Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. Y1 - 2013/04/ N1 - R835163 JF - JOURNAL OF REPRODUCTIVE IMMUNOLOGY J1 - J REPROD IMMUNOL VL - 97 IS - 2 SP - 211 EP - 216 ER - TY - JOUR A1 - Denny, K J A1 - Jeanes, A A1 - Fathe, K A1 - Finnell, R H A1 - Taylor, S M A1 - Woodruff, T M T1 - Neural tube defects, folate, and immune modulation. Y1 - 2013/09/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 97 IS - 9 SP - 602 EP - 609 ER - TY - JOUR A1 - Denny, K J A1 - Kelly, C F A1 - Kumar, V A1 - Witham, K L A1 - Cabrera, R M A1 - Finnell, R H A1 - Taylor, S M A1 - Jeanes, A A1 - Woodruff, T M T1 - Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Y1 - 2016/03/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 106 IS - 3 SP - 201 EP - 207 ER - TY - JOUR A1 - Farkas, S A A1 - Bottiger, A K A1 - Isaksson, H S A1 - Finnell, R H A1 - Ren, A A1 - Nilsson, T K T1 - Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. Y1 - 2013/03/ N1 - R835163 JF - EPIGENETICS J1 - CIBA F SYMP J2 - Epigenetics J3 - Epigenetics VL - 8 IS - 3 SP - 303 EP - 316 ER - TY - JOUR A1 - Fathe, K A1 - Palacios, A A1 - Finnell, R H T1 - Brief report novel mechanism for valproate-induced teratogenicity. Y1 - 2014/08/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 100 IS - 8 SP - 592 EP - 597 ER - TY - JOUR A1 - Gulvady, A A A1 - Murphy, E J A1 - Ciolino, H P A1 - Cabrera, R M A1 - Jolly, C A T1 - Glycerol-3-phosphate acyltransferase-1 gene ablation results in altered thymocyte lipid content and reduces thymic T cell production in mice. Y1 - 2013/01/ N1 - R835163 JF - LIPIDS J1 - LIPIDS VL - 48 IS - 1 SP - 3 EP - 12 ER - TY - JOUR A1 - Gulvady, A A A1 - Ciolino, H P A1 - Cabrera, R M A1 - Jolly, C A T1 - Resveratrol inhibits the deleterious effects of diet-induced obesity on thymic function. Y1 - 2013/09/ N1 - R835163 JF - THE JOURNAL OF NUTRITIONAL BIOCHEMISTRY J1 - NONE VL - 24 IS - 9 SP - 1625 EP - 1633 ER - TY - JOUR A1 - Hansler, A A1 - Chen, Q A1 - Gray, J D A1 - Ross, M E A1 - Finnell, R H A1 - Gross, S S T1 - Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Y1 - 2014/08/ N1 - R835163 JF - BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY VL - 100 IS - 8 SP - 623 EP - 632 ER - TY - JOUR A1 - Hen, N A1 - Shekh-Ahmad, T A1 - Yagen, B A1 - McDonough, J H A1 - Finnell, R H A1 - Wlodarczyk, B A1 - Bialer, M T1 - Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. Y1 - 2013/08/22 N1 - R835163 JF - JOURNAL OF MEDICINAL CHEMISTRY J1 - J MED CHEM VL - 156 IS - 16 SP - 6467 EP - 6477 ER - TY - JOUR A1 - Kur, E A1 - Mecklenburg, N A1 - Cabrera, R M A1 - Willnow, T E A1 - Hammes, A T1 - LRP2 mediates folate uptake in the developing neural tube. Y1 - 2014/05/15 N1 - R835163 JF - JOURNAL OF CELL SCIENCE J1 - J CELL SCI VL - 127 IS - Pt 10 SP - 2261 EP - 2268 ER - TY - JOUR A1 - Lai, S A1 - Nakayama, Y A1 - Sequeira, J M A1 - Wlodarczyk, B J A1 - Cabrera, R M A1 - Finnell, R H A1 - Bottiglieri, T A1 - Quadros, E V T1 - The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. Y1 - 2013/06/2013 N1 - R835163 JF - FASEB JOURNAL J1 - FASEB J J2 - FASEB Journal VL - 27 IS - 6 SP - 2468 EP - 2475 ER - TY - JOUR A1 - Lei, Y A1 - Zhu, H A1 - Duhon, C A1 - Yang, W A1 - Ross, M E A1 - Shaw, G M A1 - Finnell, R H T1 - Mutations in planar cell polarity gene SCRIB are associated with spina bifida. Y1 - 2013/07/26 N1 - R835163 JF - PLOS ONE J1 - PLOS One VL - 8 IS - 7 SP - e69262 (8 pp.) ER - TY - JOUR A1 - Lei, Y A1 - Zhu, H A1 - Yang, W A1 - Ross, M E A1 - Shaw, G M A1 - Finnell, R H T1 - Identification of novel CELSR1 mutations in spina bifida. Y1 - 2014/03/14 N1 - R835163 JF - PLOS ONE J1 - PLOS One VL - 9 IS - 3 SP - e92207 (8 pp.) ER - TY - JOUR A1 - Lupo, P J A1 - Canfield, M A A1 - Chapa, C A1 - Lu, W A1 - Agopian, A J A1 - Mitchell, L E A1 - Shaw, G M A1 - Waller, D K A1 - Olshan, A F A1 - Finnell, R H A1 - Zhu, H T1 - Diabetes and obesity-related genes and the risk of neural tube defects in the National Birth Defects Prevention Study. Y1 - 2012/12/15 N1 - R835163 JF - AMERICAN JOURNAL OF EPIDEMIOLOGY J1 - AM J EPIDEMIOL J2 - Am.J.Epidemiol. J3 - American Journal of Epidemiology J4 - American Journal of Epidemiology VL - 176 IS - 12 SP - 1101 EP - 1109 ER - TY - JOUR A1 - Lupo, P J A1 - Chapa, C A1 - Nousome, D A1 - Duhon, C A1 - Canfield, M A A1 - Shaw, G M A1 - Finnell, R H A1 - Zhu, H A1 - National Bith Defect Prevention Study, T1 - A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. Y1 - 2012/11/ N1 - R835163 JF - MOLECULAR GENETICS AND METABOLISM J1 - MOL GENET METAB VL - 107 IS - 3 SP - 592 EP - 595 ER - TY - JOUR A1 - Lupo, P J A1 - Mitchell, L E A1 - Canfield, M A A1 - Shaw, G M A1 - Olshan, A F A1 - Finnell, R H A1 - Zhu, H A1 - National Birth Defects Prevention Study, T1 - Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects. Y1 - 2014/01/ N1 - R835163 VL - 111 IS - 1 SP - 46 EP - 51 ER - TY - JOUR A1 - Martinez-Una, M A1 - Varela-Rey, M A1 - Cano, A A1 - Fernandez-Ares, L A1 - Beraza, N A1 - Aurrekoetxea, I A1 - Martinez-Arranz, I A1 - Garcia-Rodriguez, J L A1 - Buque, X A1 - Mestre, D A1 - Luka, Z A1 - Wagner, C A1 - Alonso, C A1 - Finnell, R H A1 - Lu, S C A1 - Martinez-Chantar, M L A1 - Aspichueta, P A1 - Mato, J M T1 - Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Y1 - 2013/10/ N1 - R835163 JF - HEPATOLOGY J1 - HEPATOLOGY VL - 58 IS - 4 SP - 1296 EP - 1305 ER - TY - JOUR A1 - Martinez-Una, M A1 - Varela-Rey, M A1 - Mestre, D A1 - Fernandez-Ares, L A1 - Fresnedo, O A1 - Fernandez-Ramos, D A1 - Gutierrez-de Juan, V A1 - Martin-Guerrero, I A1 - Garcia-Orad, A A1 - Luka, Z A1 - Wagner, C A1 - Lu, S C A1 - Garcia-Monzon, C A1 - Finnell, R H A1 - Aurrekoetxea, I A1 - Buque, X A1 - Martinez-Chantar, M L A1 - Mato, J M A1 - Aspichueta, P T1 - S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. Y1 - 2015/03/ N1 - R835163 JF - JOURNAL OF HEPATOLOGY J1 - J HEPATOL VL - 62 IS - 3 SP - 673 EP - 681 ER - TY - JOUR A1 - Shawlot, W A1 - Vazquez-Chantada, M A1 - Wallingford, J B A1 - Finnell, R H T1 - Rfx2 is required for spermatogenesis in the mouse. Y1 - 2015/09/ N1 - R835163 JF - GENESIS J1 - GENESIS VL - 53 IS - 9 SP - 604 EP - 611 ER - TY - JOUR A1 - Shekh-Ahmad, T A1 - Mawasi, H A1 - McDonough, J H A1 - Finnell, R H A1 - Wlodarczyk, B J A1 - Yavin, E A1 - Bialer, M T1 - Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Y1 - 2014/12/ N1 - R835163 JF - EPILEPSIA J1 - EPILEPSIA VL - 55 IS - 12 SP - 1944 EP - 1952 ER - TY - JOUR A1 - Shekh-Ahmad, T A1 - Hen, N A1 - Yagen, B A1 - McDonough, J H A1 - Finnell, R H A1 - Wlodarczyk, B J A1 - Bialer, M T1 - Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Y1 - 2014/02/ N1 - R835163 VL - 55 IS - 2 SP - 353 EP - 361 ER - TY - JOUR A1 - Tabler, J M A1 - Barrell, W B A1 - Szabo-Rogers, H L A1 - Healy, C A1 - Yeung, Y A1 - Perdiguero, E G A1 - Schulz, C A1 - Yannakoudakis, B Z A1 - Mesbahi, A A1 - Wlodarczyk, B A1 - Geissmann, F A1 - Finnell, R H A1 - Wallingford, J B A1 - Liu, K J T1 - Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Y1 - 2013/06/24 N1 - R835163 JF - DEVELOPMENTAL CELL VL - 25 IS - 6 SP - 623 EP - 635 ER - TY - JOUR A1 - Tsurubuchi, T A1 - Allender, E V A1 - Siddiqui, M R A1 - Shim, K W A1 - Ichi, S A1 - Boshnjaku, V A1 - Mania-Farnell, B A1 - Xi, G A1 - Finnell, R H A1 - McLone, D G A1 - Tmita, T A1 - Mayanil, C S T1 - A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8-/- embryos. Y1 - 2014/08/ N1 - R835163 JF - CHILD'S NERVOUS SYSTEM VL - 30 IS - 8 SP - 1343 EP - 1353 ER - TY - JOUR A1 - Wallingford, J B A1 - Niswander, L A A1 - Shaw, G M A1 - Finnell, R H T1 - The continuing challenge of understanding, preventing, and treating neural tube defects. Y1 - 2013/03/1 N1 - R835163 JF - SCIENCE J1 - SCIENCE VL - 339 IS - 6123 SP - 1222002 (7 pp.) ER - TY - JOUR A1 - Wang, B A1 - Jin, L A1 - Ren, A A1 - Yuan, Y A1 - Liu, J A1 - Li, Z A1 - Zhang, L A1 - Yi, D A1 - Wang, L L A1 - Zhang, Y A1 - Wang, X A1 - Tao, S A1 - Finnell, R H T1 - Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Y1 - 2015/01/6 N1 - R835163 JF - ENVIRONMENTAL SCIENCE & TECHNOLOGY VL - 49 IS - 1 SP - 588 EP - 596 ER - TY - JOUR A1 - Wang, B A1 - Jin, L A1 - Ren, A A1 - Yuan, Y A1 - Liu, J A1 - Li, Z A1 - Zhang, L A1 - Yi, D A1 - Wang, L L A1 - Zhang, Y A1 - Wang, X A1 - Tao, S A1 - Finnell, R H T1 - Correction to levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Y1 - 2015/09/1 N1 - R835163 JF - ENVIRONMENTAL SCIENCE & TECHNOLOGY VL - 49 IS - 17 SP - 10754 EP - 10755 ER - TY - JOUR A1 - Wang, X A1 - Cabrera, R M A1 - Li, Y A1 - Miller, D S A1 - Finnell, R H T1 - Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice. Y1 - 2013/03/ N1 - R835163 JF - FASEB JOURNAL J1 - FASEB J J2 - FASEB Journal VL - 27 IS - 3 SP - 1167 EP - 1175 ER - TY - JOUR A1 - Wlodarczyk, B J A1 - Zhu, H A1 - Finnell, R H T1 - Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Y1 - 2014/02/15 N1 - R835163 JF - TOXICOLOGY AND APPLIED PHARMACOLOGY J1 - TOXICOL APPL PHARM J2 - Toxicol.Appl.Pharmacol. J3 - Toxicol Appl Pharmacol J4 - Toxicology and Applied Pharmacology VL - 275 IS - 1 SP - 22 EP - 27 ER - TY - JOUR A1 - Wlodarczyk, B A1 - Spiegelstein, O A1 - Hill, D A1 - Le, X C A1 - Finnell, R H T1 - Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Y1 - 2012/12/17 N1 - R835163 JF - TOXICOLOGY LETTERS J1 - TOXICOL LETT VL - 215 IS - 3 SP - 214 EP - 218 ER - TY - JOUR A1 - Yi, D A1 - Yuan, Y A1 - Jin, L A1 - Zhou, G A1 - Zhu, H A1 - Finnell, R H A1 - Ren, A T1 - Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population. Y1 - 2015/01/ N1 - R835163 JF - NEUROTOXICOLOGY J1 - NEUROTOXICOLOGY VL - 46 SP - 73 EP - 78 ER - TY - JOUR A1 - Yuan, Y A1 - Jin, L A1 - Wang, L A1 - Li, Z A1 - Zhang, L A1 - Zhu, H A1 - Finnell, R H A1 - Zhou, G A1 - Ren, A T1 - Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Y1 - 2013/06/2013 N1 - R835163 JF - REPRODUCTIVE TOXICOLOGY J1 - ADV EXP MED BIOL J2 - REPROD TOXICOL J3 - Reproductive Toxicology VL - 37 SP - 70 EP - 75 ER - TY - CONF A1 - Finnell, R H T1 - Keynote address. Y1 - 2011/05/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - Novel tools and technologies for stem cells and regenerative medicine. Y1 - 2012/01/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - From reproductive safety to drug development: use of embryonic stem cell screening paradigms. Y1 - 2012/03/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - From man to mouse and back again: efforts to develop novel interventions for pediatric neurological disorders. Y1 - 2013/12/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - From reproductive safety to drug development: use of embryonic Stem Cell Screening Paradigms. Y1 - 2013/06/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - Teratogenicity of antiepileptic drugs: efforts to prevent preventable birth defects. Y1 - 2013/03/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - From reproductive safety to drug development: use of embryonic stem cell screening paradigms. Y1 - 2013/05/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - Rational drug design: first steps to avoid adverse effects of drugs in pregnancy. Y1 - 2014/02/ N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - Nutrients, vitamins and stem cells: today’s toolkit for preventing preventable birth defects. Y1 - 2015/02/4 N1 - R835163 ER - TY - CONF A1 - Finnell, R H T1 - Is valproic acid such a terrible teratogen? From the basic science point of view. Y1 - 2016/09/12 N1 - R835163 ER -