TY - Abstract A1 - Lewandowski, T A A1 - Bartell, S M A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - Effect of tissue binding uncertainty on a PBTK model of methylmercury in the fetal rat Y1 - 1998/07/ N1 - R825358 VL - 95 IS - Suppl 1 SP - 130 ER - TY - Abstract A1 - Lewandowski, T A A1 - Bartell, S M A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - Toxicokinetic and toxicodynamic modeling of the effects of methylmercury on the fetal rat Y1 - 1998// N1 - R825173 N1 - R825358 VL - 42 SP - 139 ER - TY - Abstract A1 - Lewandowski, T A A1 - Ponce, R A A1 - Hong, S A1 - Bartell, S M A1 - Faustman, E M T1 - Biologically-based dose-response model for methylmercury developmental toxicity incorporating novel in vivo cell cycling data Y1 - 2000// N1 - R825358 VL - 54 SP - 1370 ER - TY - Abstract A1 - Lewandowski, T A A1 - Schroeder, J L A1 - Ponce, R A A1 - Bartell, S M A1 - Faustman, E M T1 - In vivo determination of cell cycling rates in embryonic rat neural cells: development of a biologically-based toxicodynamic model for methylmercury risk assessment N1 - R825358 ER - TY - Abstract A1 - Lu, S A1 - Kavanagh, T J A1 - Faustman, E M T1 - Methylmercury's effects on mitochondrial DNA in developing rodent midbrain. Y1 - 2000// N1 - R825358 JF - THE TOXICOLOGIST VL - 54 SP - 162 ER - TY - Abstract A1 - McMillan, M J A1 - Ponce, R A A1 - Kirchner, S C A1 - Hunt, K A A1 - Hong, S A1 - Ou, Y C A1 - Faustman, E M T1 - Cell cycle phase-specific expression of cell cycle regulatory genes in rodent embryonic neuroepithelial cells exposed to methylmercury Y1 - 1998// N1 - R825358 VL - 57 SP - 225 ER - TY - Abstract A1 - Mendoza, M A A1 - Ponce, R A A1 - Ou, Y C A1 - Faustman, E M T1 - Involvement of p21WAF1/CIP1 in methlymercury induced cell cycle inhibition Y1 - 2000// N1 - R825358 VL - 54 SP - 238 ER - TY - Abstract A1 - Mendoza, M A1 - Ou, Y C A1 - Hong, S A1 - Faustman, E M T1 - A p53 independent methyl mercury-induced G2/M arrest Y1 - 1999// N1 - R825358 VL - 48 SP - 282 ER - TY - Abstract A1 - Ou, Y C A1 - Lu, S A1 - Faustman, E M T1 - Induction of necrotic and apoptotic cell death following methylmercyr (MeHg) exposure in primary embryonic CNS cells. Y1 - 1998// N1 - R825358 JF - THE TOXICOLOGIST VL - 42 IS - 1-S SP - 196 ER - TY - Abstract A1 - Ponce, R A A1 - Bartell, S M A1 - Sanga, R N A1 - Faustman, E M T1 - Comparative analyses of exposure estimates based on biomarkers or predictive models: a case example with dietary methylmercury intake Y1 - 1998/07/ N1 - R825358 VL - 95 IS - Suppl 1 SP - 131 EP - 132 ER - TY - CHAP A1 - Lewandowski, T A A1 - Ponce, R A A1 - Whittaker, S G A1 - Faustman, E M T1 - In vitro models for evaluating developmental toxicity. Y1 - 2000// N1 - R825358 SP - 139 EP - 185 PB - Taylor & Francis ER - TY - JOUR A1 - Lewandowski, T A A1 - Pierce, C H A1 - Pingree, S D A1 - Hong, S A1 - Faustman, E M T1 - Methylmercury distribution in the pregnant rat and embryo during early midbrain organogenesis. Y1 - 2002/11/ N1 - R825358 N1 - R826886 JF - TERATOLOGY J1 - TERATOLOGY VL - 66 IS - 5 SP - 235 EP - 241 ER - TY - JOUR A1 - Lewandowski, T A A1 - Ponce, R A A1 - Charleston, J S A1 - Hong, S A1 - Faustman, E M T1 - Changes in cell cycle kinetics and cell number in the rat midbrain during organogenesis. Y1 - 2003/09/1 N1 - R825358 VL - 75 IS - 1 SP - 124 EP - 133 ER - TY - JOUR A1 - Mendoza, M A1 - Ponce, R A A1 - Ou, Y C A1 - Faustman, E M T1 - p21WAF1/CIP1 inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure. Y1 - 2002/01/ N1 - R825358 N1 - R826886 JF - TOXICOLOGY AND APPLIED PHARMACOLOGY J1 - TOXICOL APPL PHARM J2 - Toxicol.Appl.Pharmacol. J3 - Toxicol Appl Pharmacol J4 - Toxicology and Applied Pharmacology VL - 178 IS - 2 SP - 117 EP - 125 ER - TY - JOUR A1 - Ou, Y C A1 - Thompson, S A A1 - Ponce, R A A1 - Schroeder, J A1 - Kavanagh, T J A1 - Faustman, E M T1 - Induction of the cell cycle regulatory gene p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. Y1 - 1999/06/15 N1 - R825358 N1 - R826886 JF - TOXICOLOGY AND APPLIED PHARMACOLOGY J1 - TOXICOL APPL PHARM J2 - Toxicol.Appl.Pharmacol. J3 - Toxicol Appl Pharmacol J4 - Toxicology and Applied Pharmacology VL - 157 IS - 3 SP - 203 EP - 212 ER - TY - JOUR A1 - Ou, Y C A1 - White, C C A1 - Krejsa, C M A1 - Ponce, R A A1 - Kavanagh, T J A1 - Faustman, E M T1 - The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Y1 - 1999/10/ N1 - R825358 N1 - R826886 JF - NEUROTOXICOLOGY J1 - NEUROTOXICOLOGY VL - 20 IS - 5 SP - 793 EP - 804 ER - TY - SER A1 - Lewandowski, T A A1 - Bartell, S M A1 - Ponce, R A A1 - Faustman, E M T1 - Linking mechanism-based toxicokinetic and toxicodynamic models for neurodevelopmental toxicity. N1 - R825358 ER - TY - SER A1 - Lewandowski, T A A1 - Bartell, S M A1 - Ponce, R A A1 - Faustman, E M T1 - Use of physiological and toxicological data in a biologically-based model of methylmercury developmental toxicity. N1 - R825358 ER - TY - CONF A1 - Bartell, S M A1 - Ponce, R A A1 - Sanga, R N A1 - Faustman, E M T1 - Human variability in steady state blood-to-hair, blood-to-intake, and hair-to-intake ratios for mercury: implications for health risk assessment N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Ponce, R A A1 - Hong, S A1 - Bartell, S M A1 - Faustman, E M T1 - Biologically-based dose-response model for methylmercury developmental toxicity incorporating novel in vivo cell cycling data N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Bartell, S M A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - Effect of tissue binding uncertainty on a PBTK model of methylmercury in the fetal rat N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Schroeder, J L A1 - Ponce, R A A1 - Bartell, S M A1 - Faustman, E M T1 - In vivo determination of cell cycling rates in embryonic rat neural cells: development of a biologically-based toxicodynamic model for methylmercury risk assessment N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Hong, S W A1 - Pingree, S A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - Methylmercury distribution in pregnant rats and their fetuses during early organogenesis N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Bartell, S M A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - PBTK model of methylmercury toxicity in the fetal rat N1 - R825358 ER - TY - CONF A1 - Lewandowski, T A A1 - Bartell, S M A1 - Pierce, C H A1 - Ponce, R A A1 - Faustman, E M T1 - Toxicokinetic and toxicodynamic modeling of the effects of methylmercury on the fetal rat N1 - R825358 ER - TY - CONF A1 - Lu, S J A1 - McMillan, M J A1 - Kirchner, S C A1 - Ou, Y C A1 - Faustman, E M T1 - Mechanisms of methylmercury-induced cell cycle arrest and cell death in primary embryonic cells. N1 - R825358 ER - TY - CONF A1 - Lu, S A1 - Kavanagh, T J A1 - Faustman, E M T1 - Methlymercury's effects on mitochondrial DNA in developing rodent midbrain N1 - R825358 ER - TY - CONF A1 - McMillan, M J A1 - Ponce, R A A1 - Kirchner, S C A1 - Hunt, K A A1 - Hong, S A1 - Ou, Y C A1 - Faustman, E M T1 - Cell cycle phase-specific expression of cell cycle regulatory genes in rodent embryonic neuroepithelial cells exposed to methylmercury N1 - R825358 ER - TY - CONF A1 - Mendoza, M A A1 - Ponce, R A A1 - Ou, Y C A1 - Faustman, E M T1 - Involvement of p21WAF1/CIP1 in methlymercury induced cell cycle inhibition N1 - R825358 ER - TY - CONF A1 - Mendoza, M A1 - Ou, Y C A1 - Hong, S A1 - Faustman, E M T1 - A p53 independent methyl mercury-induced G2/M arrest N1 - R825358 ER - TY - CONF A1 - Ponce, R A A1 - Bartell, S M A1 - Sanga, R N A1 - Faustman, E M T1 - Comparative analyses of exposure estimates based on biomarkers or predictive models: a case example with dietary methylmercury intake N1 - R825358 ER -